CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice (Q35572404)

8 August 2017

title

CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice (English)

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8 August 2017

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22

Tobias Junt

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Caroline Fecher

Caroline Fecher

9

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Irmgard Förster

Irmgard Förster

19

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Christoph J Binder

Christoph J Binder

12

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Thomas Korn

Thomas Korn

17

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Steffen Jung

Steffen Jung

16

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Christian Weber

Christian Weber

1

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Alma Zernecke

23

Alma Zernecke

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8 August 2017

8

Kiril Bidzhekov

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8 August 2017

6

Remco T A Megens

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8 August 2017

2

Svenja Meiler

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8 August 2017

5

Maik Drechsler

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8 August 2017

Marc A M J van Zandvoort

11

Marc A M J van Zandvoort

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8 August 2017

Yvonne Döring

3

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8 August 2017

Miriam Koch

4

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8 August 2017

Zuzanna Rowinska

7

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8 August 2017

Eliana Ribechini

10

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8 August 2017

Ivett Jelinek

13

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8 August 2017

Mihail Hristov

14

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8 August 2017

Louis Boon

15

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8 August 2017

Manfred B Lutz

18

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8 August 2017

Martin Zenke

20

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8 August 2017

Thomas Hieronymus

21

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8 August 2017

Tobias Junt

22

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8 August 2017

language of work or name

English

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publication date

1 July 2011

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Journal of Clinical Investigation

8 August 2017

published in

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8 August 2017

volume

121

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8 August 2017

issue

7

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8 August 2017

page(s)

2898-2910

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Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity

8 August 2017

cites work

1 reference

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CD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophages.

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Low-grade chronic inflammation in regions of the normal mouse arterial intima predisposed to atherosclerosis

12 July 2018

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12 July 2018

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12 July 2018

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IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

12 July 2018

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Stat5a/b are essential for normal lymphoid development and differentiation

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis

12 July 2018

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12 July 2018

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Activation of phosphoinositide 3-kinases by the CCR4 ligand macrophage-derived chemokine is a dispensable signal for T lymphocyte chemotaxis

12 July 2018

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Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.

12 July 2018

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ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: implications towards sensitization to apoptosis.

12 July 2018

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Quantitative differences in chemokine receptor engagement generate diversity in integrin-dependent lymphocyte adhesion

12 July 2018

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The role of chemokine receptors in primary, effector, and memory immune responses

12 July 2018

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A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock

12 July 2018

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Inhibition of interleukin 2 signaling and signal transducer and activator of transcription (STAT)5 activation during T cell receptor-mediated feedback inhibition of T cell expansion

12 July 2018

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The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells

12 July 2018

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STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation.

12 July 2018

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Vaccination using oxidized low-density lipoprotein-pulsed dendritic cells reduces atherosclerosis in LDL receptor-deficient mice.

12 July 2018

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Attenuated atherosclerosis upon IL-17R signaling disruption in LDLr deficient mice.

26 September 2018

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Macrophage apoptosis exerts divergent effects on atherogenesis as a function of lesion stage.

26 September 2018

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Lack of conventional dendritic cells is compatible with normal development and T cell homeostasis, but causes myeloid proliferative syndrome

26 September 2018

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CD11c(+) dendritic cells maintain antigen processing, presentation capabilities, and CD4(+) T-cell priming efficacy under hypercholesterolemic conditions associated with atherosclerosis

26 September 2018

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Human anti-inflammatory macrophages induce Foxp3+ GITR+ CD25+ regulatory T cells, which suppress via membrane-bound TGFbeta-1.

26 September 2018

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Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule.

26 September 2018

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Exposure to TARC alters beta2-adrenergic receptor signaling in human peripheral blood T lymphocytes

26 September 2018

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Progressive and controlled development of mouse dendritic cells from Flt3+CD11b+ progenitors in vitro.

26 September 2018

1 reference

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Dyslipidemia associated with atherosclerotic disease systemically alters dendritic cell mobilization

26 September 2018

1 reference

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Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen.

26 September 2018

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Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells

26 September 2018

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C-C chemokine receptor 4 expression defines a major subset of circulating nonintestinal memory T cells of both Th1 and Th2 potential.

26 September 2018

1 reference

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Natural regulatory T cells control the development of atherosclerosis in mice

26 September 2018

1 reference

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The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors

15 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21633167

12 December 2020

Orthotopic aortic transplantation in mice: a new model of allograft arteriosclerosis

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12 December 2020

Oligoclonal T cell expansions in atherosclerotic lesions of apolipoprotein E-deficient mice

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https://pubmed.ncbi.nlm.nih.gov/21633167

12 December 2020

Transfer of CD4(+) T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice

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12 December 2020

Network of vascular-associated dendritic cells in intima of healthy young individuals

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12 December 2020

Linked Chromosome 16q13 Chemokines, Macrophage-Derived Chemokine, Fractalkine, and Thymus- and Activation-Regulated Chemokine, Are Expressed in Human Atherosclerotic Lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/21633167

12 December 2020

Effects of oxidised low density lipoprotein on dendritic cells: a possible immunoregulatory component of the atherogenic micro-environment?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21633167

12 December 2020

An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction

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https://pubmed.ncbi.nlm.nih.gov/21633167

12 December 2020

Protective Role of Interleukin-10 in Atherosclerosis

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https://pubmed.ncbi.nlm.nih.gov/21633167

12 December 2020

CCR4-deficient mice show prolonged graft survival in a chronic cardiac transplant rejection model

1 reference

https://pubmed.ncbi.nlm.nih.gov/21633167

12 December 2020

Chemokine receptor 7 knockout attenuates atherosclerotic plaque development

1 reference

https://pubmed.ncbi.nlm.nih.gov/21633167

12 December 2020

Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/21633167

12 December 2020

CX3CR1 deficiency impairs dendritic cell accumulation in arterial intima and reduces atherosclerotic burden

1 reference

https://pubmed.ncbi.nlm.nih.gov/21633167

12 December 2020

Identifiers

DOI

10.1172/JCI44925

1 reference

8 August 2017

1 reference

8 August 2017

1 reference