Cotranscriptional effect of a premature termination codon revealed by live-cell imaging. (Q35567460)

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15 January 2020

title

Cotranscriptional effect of a premature termination codon revealed by live-cell imaging (English)

1 reference

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15 January 2020

1

1 reference

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15 January 2020

Pamela Nicholson

series ordinal

2

1 reference

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15 January 2020

4

Robert H Singer

1 reference

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15 January 2020

author name string

Rodolfo Zamudio Orozco

series ordinal

3

1 reference

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15 January 2020

Oliver Mühlemann

series ordinal

5

1 reference

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15 January 2020

language of work or name

English

0 references

publication date

25 October 2011

1 reference

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15 January 2020

1 reference

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15 January 2020

volume

17

1 reference

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15 January 2020

issue

12

1 reference

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15 January 2020

page(s)

2094-2107

1 reference

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The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing

15 January 2020

cites work

1 reference

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A potential role for initiator-tRNA in pre-mRNA splicing regulation

12 July 2018

1 reference

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Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors

12 July 2018

1 reference

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Execution of nonsense-mediated mRNA decay: what defines a substrate?

12 July 2018

1 reference

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Nonsense codons trigger an RNA partitioning shift

12 July 2018

1 reference

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SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells

12 July 2018

1 reference

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SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan

12 July 2018

1 reference

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Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region

12 July 2018

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Functional integration of transcriptional and RNA processing machineries

12 July 2018

1 reference

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Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

12 July 2018

1 reference

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Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends

12 July 2018

1 reference

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Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA

12 July 2018

1 reference

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Communication with the exon-junction complex and activation of nonsense-mediated decay by human Upf proteins occur in the cytoplasm.

12 July 2018

1 reference

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In vivo dynamics of RNA polymerase II transcription.

12 July 2018

1 reference

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Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function

12 July 2018

1 reference

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An alternative branch of the nonsense-mediated decay pathway

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer

12 July 2018

1 reference

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The double life of UPF1 in RNA and DNA stability pathways

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Early nonsense: mRNA decay solves a translational problem

12 July 2018

1 reference

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Engineering of a monomeric green-to-red photoactivatable fluorescent protein induced by blue light

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

The human RNA surveillance factor UPF1 is required for S phase progression and genome stability

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Dynamics of transcription and mRNA export

12 July 2018

1 reference

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A GFP-based reporter system to monitor nonsense-mediated mRNA decay

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Yeast poly(A)-binding protein, Pab1, and PAN, a poly(A) nuclease complex recruited by Pab1, connect mRNA biogenesis to export

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

A synthetic A tail rescues yeast nuclear accumulation of a ribozyme-terminated transcript

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Stop codon-mediated suppression of splicing is a novel nuclear scanning mechanism not affected by elements of protein synthesis and NMD.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Efficient downregulation of immunoglobulin mu mRNA with premature translation-termination codons requires the 5'-half of the VDJ exon

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

The pioneer translation initiation complex is functionally distinct from but structurally overlaps with the steady-state translation initiation complex

12 July 2018

1 reference

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Regulation of splicing: the importance of being translatable

12 July 2018

1 reference

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Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Single mRNA molecules demonstrate probabilistic movement in living mammalian cells

12 July 2018

1 reference

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Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Intranuclear degradation of nonsense codon-containing mRNA

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Precise nanometer localization analysis for individual fluorescent probes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Stop codons affect 5' splice site selection by surveillance of splicing

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Quality control of mRNA 3'-end processing is linked to the nuclear exosome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Coupled transcription and translation within nuclei of mammalian cells.

12 July 2018

1 reference

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Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Inefficient processing impairs release of RNA from the site of transcription

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Localization of ASH1 mRNA particles in living yeast

12 July 2018

1 reference

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Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm

12 July 2018

1 reference

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A splicing-dependent regulatory mechanism that detects translation signals

12 July 2018

1 reference

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Effects of nonsense mutations on nuclear and cytoplasmic adenine phosphoribosyltransferase RNA.

12 July 2018

1 reference

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Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Maintenance of an open reading frame as an additional level of scrutiny during splice site selection

12 July 2018

1 reference

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Functional immunoglobulin M production after transfection of cloned immunoglobulin heavy and light chain genes into lymphoid cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222123

Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion

12 July 2018

1 reference

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EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 3' UTR length

12 July 2018

1 reference

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Transcriptional silencing of nonsense codon-containing immunoglobulin minigenes

26 September 2018

1 reference

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Molecular cross-talk between the transcription, translation, and nonsense-mediated decay machineries

26 September 2018

1 reference

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Ribosome components are associated with sites of transcription.

26 September 2018

1 reference

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Alternatively spliced TCR mRNA induced by disruption of reading frame.

26 September 2018

1 reference

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Precursor RNAs harboring nonsense codons accumulate near the site of transcription

26 September 2018

1 reference

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A premature termination codon in either exon of minute virus of mice P4 promoter-generated pre-mRNA can inhibit nuclear splicing of the intervening intron in an open reading frame-dependent manner

26 September 2018

1 reference

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Proofreading and aminoacylation of tRNAs before export from the nucleus

26 September 2018

1 reference

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Nonsense-mediated mRNA decay: target genes and functional diversification of effectors

26 September 2018

1 reference

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The case for nuclear translation

24 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22028363

12 December 2020

Transcriptional silencing of nonsense codon-containing immunoglobulin micro genes requires translation of its mRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/22028363

12 December 2020

A quality control pathway that down-regulates aberrant T-cell receptor (TCR) transcripts by a mechanism requiring UPF2 and translation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22028363

12 December 2020

Nonsense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22028363

12 December 2020

Identifiers

DOI

10.1261/RNA.02918111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028363%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028363%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

22028363

1 reference