Protein interactome reveals converging molecular pathways among autism disorders (Q35203610)

7 August 2017

title

Protein interactome reveals converging molecular pathways among autism disorders (English)

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7 August 2017

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2

Chad A Shaw

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7 August 2017

Yasunari Sakai

1

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Huda Zoghbi

object named as

Huda Y Zoghbi

7

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author name string

Brian C Dawson

3

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7 August 2017

Diana V Dugas

4

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7 August 2017

Zaina Al-Mohtaseb

5

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7 August 2017

David E Hill

6

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7 August 2017

language of work or name

English

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publication date

1 June 2011

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Science Translational Medicine

7 August 2017

published in

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7 August 2017

volume

3

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7 August 2017

issue

86

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7 August 2017

page(s)

86ra49

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Enhanced polyubiquitination of Shank3 and NMDA receptor in a mouse model of autism

7 August 2017

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Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

28 July 2018

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Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

28 July 2018

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Functional impact of global rare copy number variation in autism spectrum disorders

28 July 2018

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Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation

28 July 2018

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Autism and other neuropsychiatric symptoms are prevalent in individuals with MeCP2 duplication syndrome

28 July 2018

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Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

28 July 2018

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An experimentally derived confidence score for binary protein-protein interactions

28 July 2018

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Human Protein Reference Database--2009 update

28 July 2018

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The Autistic Neuron: Troubled Translation?

28 July 2018

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Autism: many genes, common pathways?

28 July 2018

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Neuroligins and neurexins link synaptic function to cognitive disease

28 July 2018

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The Reelin signaling pathway promotes dendritic spine development in hippocampal neurons

28 July 2018

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High-quality binary protein interaction map of the yeast interactome network

28 July 2018

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28 July 2018

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Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis

28 July 2018

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MeCP2, a key contributor to neurological disease, activates and represses transcription

28 July 2018

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Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia

28 July 2018

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Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1

28 July 2018

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Structural variation of chromosomes in autism spectrum disorder

28 July 2018

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Association between microdeletion and microduplication at 16p11.2 and autism

28 July 2018

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dAtaxin-2 mediates expanded Ataxin-1-induced neurodegeneration in a Drosophila model of SCA1

28 July 2018

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A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival

28 July 2018

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Autism: highly heritable but not inherited

28 July 2018

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Strong association of de novo copy number mutations with autism

28 July 2018

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Towards a proteome-scale map of the human protein–protein interaction network

28 July 2018

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PDZ domain proteins of synapses

28 July 2018

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A map of the interactome network of the metazoan C. elegans

28 July 2018

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Postnatal Neurodevelopmental Disorders: Meeting at the Synapse?

28 July 2018

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Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

28 July 2018

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A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P

28 July 2018

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Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

28 July 2018

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Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins

28 July 2018

1 reference

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Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin

28 July 2018

1 reference

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Identification of a duplication of Xq28 associated with bilateral periventricular nodular heterotopia

28 July 2018

1 reference

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Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34

28 July 2018

1 reference

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Identification and characterization of the tuberous sclerosis gene on chromosome 16

28 July 2018

1 reference

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Cytogenetic, biochemical, and molecular analyses of a 22q13 deletion

28 July 2018

1 reference

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Exhaustive benchmarking of the yeast two-hybrid system.

28 July 2018

1 reference

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22q13.3 deletion syndrome: clinical and molecular analysis using array CGH

26 September 2018

1 reference

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Origins and functional impact of copy number variation in the human genome

26 September 2018

1 reference

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Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia

26 September 2018

1 reference

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Common genetic variants on 5p14.1 associate with autism spectrum disorders

26 September 2018

1 reference

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Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus

26 September 2018

1 reference

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Autism and brain development

26 September 2018

1 reference

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Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function

26 September 2018

1 reference

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Advances in autism genetics: on the threshold of a new neurobiology

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169432

Chromosomal microarray analysis (CMA) detects a large X chromosome deletion including FMR1, FMR2, and IDS in a female patient with mental retardation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169432

ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169432

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169432

TSC2 mediates cellular energy response to control cell growth and survival

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169432

10.1126/SCITRANSLMED.3002166

26 September 2018

Identifiers

DOI

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7 August 2017

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7 August 2017

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