Obatoclax regulates the proliferation and fusion of osteoclast precursors through the inhibition of ERK activation by RANKL (Q35188522)

7 August 2017

title

Obatoclax regulates the proliferation and fusion of osteoclast precursors through the inhibition of ERK activation by RANKL (English)

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7 August 2017

Ju Hee Oh

1

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7 August 2017

Jae Yoon Lee

2

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7 August 2017

Jin Hyeong Park

3

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7 August 2017

Jeong Hyeon No

4

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7 August 2017

Na Kyung Lee

5

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7 August 2017

language of work or name

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4 February 2015

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7 August 2017

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7 August 2017

volume

38

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7 August 2017

issue

3

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7 August 2017

page(s)

279-284

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Gene expression profiling in osteoclast precursors by insulin using microarray analysis

7 August 2017

cites work

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Pan-Bcl-2 inhibitor, GX15-070 (obatoclax), decreases human T regulatory lymphocytes while preserving effector T lymphocytes: a rationale for its use in combination immunotherapy

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DC-STAMP, the key fusion-mediating molecule in osteoclastogenesis.

13 July 2018

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Caffeine enhances osteoclast differentiation and maturation through p38 MAP kinase/Mitf and DC-STAMP/CtsK and TRAP pathway

13 July 2018

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Osteoclast fusion and regulation by RANKL-dependent and independent factors

13 July 2018

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Phase I dose finding studies of obatoclax (GX15-070), a small molecule pan-BCL-2 family antagonist, in patients with advanced solid tumors or lymphoma

13 July 2018

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Insulin stimulates osteoblast proliferation and differentiation through ERK and PI3K in MG-63 cells

13 July 2018

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A phase I study of obatoclax mesylate, a Bcl-2 antagonist, plus topotecan in solid tumor malignancies.

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Atp6v0d2 is an essential component of the osteoclast-specific proton pump that mediates extracellular acidification in bone resorption

13 July 2018

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Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax).

13 July 2018

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Role of Bcl2 in osteoclastogenesis and PTH anabolic actions in bone

13 July 2018

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NFATc1 induces osteoclast fusion via up-regulation of Atp6v0d2 and the dendritic cell-specific transmembrane protein (DC-STAMP).

13 July 2018

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RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis

13 July 2018

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RANKL-induced DC-STAMP is essential for osteoclastogenesis

13 July 2018

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Control of osteoblast function and regulation of bone mass

13 July 2018

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Osteoclast differentiation and activation

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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27 September 2018

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27 September 2018

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27 September 2018

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27 September 2018

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Interleukin-4 Reversibly Inhibits Osteoclastogenesis via Inhibition of NF-κB and Mitogen-activated Protein Kinase Signaling

27 September 2018

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15 November 2018

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12 December 2020

v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation

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12 December 2020

JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms

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12 December 2020

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12 December 2020

10.14348/MOLCELLS.2015.2340

Identifiers

DOI

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7 August 2017

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7 August 2017

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