An improved model of association for VH-VL immunoglobulin domains: asymmetries between VH and VL in the packing of some interface residues. (Q35165857)

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5 November 2019

review article

1 reference

title

An improved model of association for VH-VL immunoglobulin domains: asymmetries between VH and VL in the packing of some interface residues (English)

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5 November 2019

author

Enrique Vargas-Madrazo

series ordinal

1

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5 November 2019

author name string

Enrique Paz-García

series ordinal

2

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5 November 2019

publication date

1 May 2003

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Journal of Molecular Recognition

5 November 2019

published in

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5 November 2019

volume

16

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5 November 2019

issue

3

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5 November 2019

page(s)

113-120

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Three-Dimensional Structure of Immunoglobulins

5 November 2019

cites work

1 reference

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VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs

21 January 2018

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Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies

21 January 2018

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21 January 2018

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Three-dimensional structure of immunoglobulins

21 January 2018

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Structural basis for the preferential association of autologous immunoglobulin subunits: role of the J region of the light chain

21 January 2018

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The influence of the buried glutamine or glutamate residue in position 6 on the structure of immunoglobulin variable domains

21 January 2018

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Conformations of the third hypervariable region in the VH domain of immunoglobulins

21 January 2018

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A domain flip as a result of a single amino-acid substitution

21 January 2018

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Analysis of immunoglobulin domain interactions. Evidence for a dominant role of salt bridges

21 January 2018

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Major antigen-induced domain rearrangements in an antibody

21 January 2018

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Somatic generation of antibody diversity

21 January 2018

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A skewed distribution of amino acids at recognition sites of the hypervariable region of immunoglobulins.

21 January 2018

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Structural insights into the evolution of an antibody combining site

21 January 2018

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An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity

21 January 2018

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The Imprint of Somatic Hypermutation on the Repertoire of Human Germline V Genes

21 January 2018

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The rate-limiting steps for the folding of an antibody scFv fragment

21 January 2018

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VIR: a computational tool for analysis of immunoglobulin sequences

21 January 2018

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Functional mapping of conserved residues located at the VL and VH domain interface of a Fab

21 January 2018

1 reference

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Analysis of antibodies of known structure suggests a lack of correspondence between the residues in contact with the antigen and those modified by somatic hypermutation

21 January 2018

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Canonical structure repertoire of the antigen-binding site of immunoglobulins suggests strong geometrical restrictions associated to the mechanism of immune recognition

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JMR.613

1 reference

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5 November 2019

1 reference