Parathyroid hormone (PTH)-induced bone gain is blunted in SOST overexpressing and deficient mice (Q35156214)

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2 February 2020

title

Parathyroid hormone (PTH)-induced bone gain is blunted in SOST overexpressing and deficient mice (English)

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2 February 2020

1 reference

2

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2 February 2020

author name string

Ina Kramer

1

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2 February 2020

Anne Studer

3

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2 February 2020

Hansjoerg Keller

4

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2 February 2020

Michaela Kneissel

5

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2 February 2020

publication date

1 February 2010

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Journal of Bone and Mineral Research

2 February 2020

published in

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2 February 2020

volume

25

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2 February 2020

issue

2

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2 February 2020

page(s)

178-189

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Parathyroid hormone signaling through low-density lipoprotein-related protein 6

2 February 2020

cites work

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Control of bone mass and remodeling by PTH receptor signaling in osteocytes

13 July 2018

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Wnt signaling: a win for bone

13 July 2018

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Building bone to reverse osteoporosis and repair fractures

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Parathyroid hormone mediates bone growth through the regulation of osteoblast proliferation and differentiation

13 July 2018

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Progress, paradox, and potential: parathyroid hormone research over five decades

13 July 2018

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PTH/cAMP/PKA signaling facilitates canonical Wnt signaling via inactivation of glycogen synthase kinase-3beta in osteoblastic Saos-2 cells

13 July 2018

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Control of the SOST bone enhancer by PTH using MEF2 transcription factors

13 July 2018

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Osteocytes as dynamic multifunctional cells

13 July 2018

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Osteoporosis in men and women

13 July 2018

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The Wnt signaling pathway and bone metabolism

13 July 2018

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Molecular and cellular mechanisms of the anabolic effect of intermittent PTH

13 July 2018

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In vivo analysis of Wnt signaling in bone

13 July 2018

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Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton

13 July 2018

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PTH stimulates bone formation in mice deficient in Lrp5

13 July 2018

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Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation

13 July 2018

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The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment

13 July 2018

1 reference

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Parathyroid hormone increases beta-catenin levels through Smad3 in mouse osteoblastic cells

13 July 2018

1 reference

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Parathyroid hormone - a bone anabolic and catabolic agent

13 July 2018

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Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation

13 July 2018

1 reference

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Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis

13 July 2018

1 reference

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Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease

13 July 2018

1 reference

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Effects of parathyroid hormone on Wnt signaling pathway in bone

13 July 2018

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SOST is a target gene for PTH in bone

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153379

SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor

13 July 2018

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SOST/sclerostin, an osteocyte-derived negative regulator of bone formation

13 July 2018

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Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

13 July 2018

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Parathyroid hormone and teriparatide for the treatment of osteoporosis: a review of the evidence and suggested guidelines for its use.

13 July 2018

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Sclerostin promotes the apoptosis of human osteoblastic cells: a novel regulation of bone formation

13 July 2018

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Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

13 July 2018

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A 52-kb deletion in the SOST-MEOX1 intergenic region on 17q12-q21 is associated with van Buchem disease in the Dutch population

13 July 2018

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Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease

13 July 2018

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Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153379

Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153379

Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153379

Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153379

A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153379

Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153379

Bone anabolic effects of parathyroid hormone are blunted by deletion of the Wnt antagonist secreted frizzled-related protein-1.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153379

Generation of BAC transgenic mice

27 September 2018

1 reference

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Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism

27 September 2018

1 reference

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Bone tissue and its mineralization in aged estrogen-depleted rats after long-term intermittent treatment with parathyroid hormone (PTH) analog SDZ PTS 893 or human PTH(1-34).

27 September 2018

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Genetic variability in adult bone density among inbred strains of mice.

27 September 2018

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PTH/PTHrP receptor expression on osteoblasts and osteocytes but not resorbing bone surfaces in growing rats.

27 September 2018

1 reference

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Effects of intermittent parathyroid hormone (PTH) administration on SOST mRNA and protein in rat bone

27 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19594304

12 December 2020

Parathyroid hormone/parathyroid hormone-related peptide type 1 receptor in human bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/19594304

12 December 2020

Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19594304

12 December 2020

Anabolic action of parathyroid hormone on cortical and cancellous bone differs between axial and appendicular skeletal sites in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19594304

12 December 2020

Increased bone formation by intermittent parathyroid hormone administration is due to the stimulation of proliferation and differentiation of osteoprogenitor cells in bone marrow

1 reference

https://pubmed.ncbi.nlm.nih.gov/19594304

12 December 2020

Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19594304

12 December 2020

Identifiers

DOI

10.1359/JBMR.090730

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19594304%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19594304%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

19594304

1 reference