Functional characterization of W147A: a high-affinity interleukin-11 antagonist (Q35113678)

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5 November 2019

title

Functional characterization of W147A: a high-affinity interleukin-11 antagonist (English)

1 reference

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5 November 2019

6

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5 November 2019

author name string

Nicholas Underhill-Day

1

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5 November 2019

Lisa A McGovern

2

1 reference

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5 November 2019

Natalia Karpovich

3

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5 November 2019

Helen J Mardon

4

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5 November 2019

Victoria A Barton

5

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5 November 2019

language of work or name

English

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publication date

1 August 2003

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5 November 2019

1 reference

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5 November 2019

volume

144

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5 November 2019

issue

8

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5 November 2019

page(s)

3406-3414

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Expression and function of interleukin-11 and its receptor alpha in the human endometrium

5 November 2019

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An antagonist for the leukemia inhibitory factor receptor inhibits leukemia inhibitory factor, cardiotrophin-1, ciliary neurotrophic factor, and oncostatin M.

9 July 2018

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Functional expression of soluble human interleukin-11 (IL-11) receptor alpha and stoichiometry of in vitro IL-11 receptor complexes with gp130

9 July 2018

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Mediation of interleukin-11-dependent biological responses by a soluble form of the interleukin-11 receptor

9 July 2018

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Identification of ciliary neurotrophic factor (CNTF) residues essential for leukemia inhibitory factor receptor binding and generation of CNTF receptor antagonists.

9 July 2018

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Activation of Src-family protein tyrosine kinases and phosphatidylinositol 3-kinase in 3T3-L1 mouse preadipocytes by interleukin-11.

9 July 2018

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Saturation mutagenesis of the human interleukin 6 receptor-binding site: implications for its three-dimensional structure

9 July 2018

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9 July 2018

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Effect of recombinant human interleukin-11 on rat megakaryopoiesis and thrombopoiesis in vivo: comparative study with interleukin-6.

9 July 2018

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

9 July 2018

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Ciliary neurotropic factor, interleukin 11, leukemia inhibitory factor, and oncostatin M are growth factors for human myeloma cell lines using the interleukin 6 signal transducer gp130

9 July 2018

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Regulation of bone marrow stromal cell differentiation by cytokines whose receptors share the gp130 protein

9 July 2018

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Regulation of lipoprotein lipase synthesis in 3T3-L1 adipocytes by interleukin-11/adipogenesis inhibitory factor.

9 July 2018

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9 July 2018

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Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction

9 July 2018

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9 July 2018

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9 July 2018

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Identification of two novel regions of human IL-6 responsible for receptor binding and signal transduction.

9 July 2018

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9 July 2018

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Generation of interleukin-6 receptor antagonists by molecular-modeling guided mutagenesis of residues important for gp130 activation

9 July 2018

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Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells

9 July 2018

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Interleukin-11 induces complex formation of Grb2, Fyn, and JAK2 in 3T3L1 cells

9 July 2018

1 reference

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Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor

9 July 2018

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Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system

9 July 2018

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Molecular cloning and expression of an IL-6 signal transducer, gp130

9 July 2018

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Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine

9 July 2018

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Molecular cloning of cDNA encoding adipogenesis inhibitory factor and identity with interleukin-11

9 July 2018

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Neuropoietic cytokines in the hematopoietic fold

9 July 2018

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Molecular cloning of a murine IL-6 receptor-associated signal transducer, gp130, and its regulated expression in vivo

9 July 2018

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Isolation and purification of human endometrial stromal and glandular cells using immunomagnetic microspheres

9 July 2018

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Cytokine receptors and signal transduction

9 July 2018

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Interleukin 11 advances progesterone-induced decidualization of human endometrial stromal cells

9 July 2018

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Interleukin-11 enhances cell survival of decidualized normal human endometrial stromal cells

27 September 2018

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Alteration in the frequency, severity and duration of chemotherapy-induced mucositis in hamsters by interleukin-11.

27 September 2018

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Leukemia inhibitory factor determines the growth status of injured adult sensory neurons

27 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/12865319

12 December 2020

Receptor engagement by viral interleukin-6 encoded by Kaposi sarcoma-associated herpesvirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12865319

12 December 2020

Fast and sensitive detection of protein and DNA bands by treatment with potassium permanganate

1 reference

https://pubmed.ncbi.nlm.nih.gov/12865319

12 December 2020

Structure-function analysis of human IL-6. Epitope mapping of neutralizing monoclonal antibodies with amino- and carboxyl-terminal deletion mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/12865319

12 December 2020

Interleukin-11 regulates the hepatic expression of the same plasma protein genes as interleukin-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/12865319

12 December 2020

Involvement of the Arg179 in the active site of human IL-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/12865319

12 December 2020

Definition of a Composite Binding Site for gp130 in Human Interleukin-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/12865319

12 December 2020

Aromatase expression in endometriosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12865319

12 December 2020

Characterization of the receptor binding sites of human leukemia inhibitory factor and creation of antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/12865319

12 December 2020

Protein tyrosine phosphorylation and activation of primary response genes by interleukin 11 in B9-TY1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12865319

12 December 2020

Localization of functional receptor epitopes on the structure of ciliary neurotrophic factor indicates a conserved, function-related epitope topography among helical cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12865319

12 December 2020

Aromatase P450 gene expression in human adipose tissue. Role of a Jak/STAT pathway in regulation of the adipose-specific promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/12865319

12 December 2020

Expression of interleukin-11 during the human menstrual cycle: coincidence with stromal cell decidualization and relationship to leukaemia inhibitory factor and prolactin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12865319

12 December 2020

Identifiers

DOI

10.1210/EN.2002-0144

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12865319%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

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5 November 2019

PubMed publication ID

12865319

1 reference