The loss of activating transcription factor 4 (ATF4) reduces bone toughness and fracture toughness (Q35089416)

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7 March 2020

title

The loss of activating transcription factor 4 (ATF4) reduces bone toughness and fracture toughness (English)

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7 March 2020

1 reference

1

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7 March 2020

Jeffry S. Nyman

9

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7 March 2020

author name string

Sasidhar Uppuganti

2

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7 March 2020

Sandra A Wadeer

3

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7 March 2020

Jack M Whitehead

4

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7 March 2020

Barbara J Rowland

5

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7 March 2020

Mathilde Granke

6

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7 March 2020

Anita Mahadevan-Jansen

7

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7 March 2020

Xiangli Yang

8

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7 March 2020

publication date

7 February 2014

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7 March 2020

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7 March 2020

volume

62

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page(s)

1-9

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Polarization control of Raman spectroscopy optimizes the assessment of bone tissue

7 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Bone fragility beyond strength and mineral density: Raman spectroscopy predicts femoral fracture toughness in a murine model of rheumatoid arthritis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

miR-214 targets ATF4 to inhibit bone formation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Three-dimensional imaging of collagen fibril organization in rat circumferential lamellar bone using a dual beam electron microscope reveals ordered and disordered sub-lamellar structures

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Dilatational band formation in bone

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Transforming growth factor β suppresses osteoblast differentiation via the vimentin activating transcription factor 4 (ATF4) axis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Matrix metalloproteinase-13 is required for osteocytic perilacunar remodeling and maintains bone fracture resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Increased susceptibility to microdamage in Brtl/+ mouse model for osteogenesis imperfecta

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Raman spectroscopy detects deterioration in biomechanical properties of bone in a glucocorticoid-treated mouse model of rheumatoid arthritis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Characterization of the effects of x-ray irradiation on the hierarchical structure and mechanical properties of human cortical bone

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Differential effects between the loss of MMP-2 and MMP-9 on structural and tissue-level properties of bone

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Measuring differences in compositional properties of bone tissue by confocal Raman spectroscopy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Changes in cortical bone response to high-fat diet from adolescence to adulthood in mice.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Osteopontin deficiency increases bone fragility but preserves bone mass

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Reduced size-independent mechanical properties of cortical bone in high-fat diet-induced obesity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Critical role of activating transcription factor 4 in the anabolic actions of parathyroid hormone in bone

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Measurement of the toughness of bone: a tutorial with special reference to small animal studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Effect of Ca2+ ions on the adhesion and mechanical properties of adsorbed layers of human osteopontin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Parathyroid hormone increases activating transcription factor 4 expression and activity in osteoblasts: requirement for osteocalcin gene expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

TGF-beta regulates the mechanical properties and composition of bone matrix

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Sacrificial bonds and hidden length dissipate energy as mineralized fibrils separate during bone fracture

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Cooperative interactions between activating transcription factor 4 and Runx2/Cbfa1 stimulate osteoblast-specific osteocalcin gene expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Transforming growth factor-beta1 to the bone

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

The contribution of the organic matrix to bone's material properties

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Ten year probabilities of osteoporotic fractures according to BMD and diagnostic thresholds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Accumulation of in-vivo fatigue microdamage and its relation to biomechanical properties in ageing human cortical bone

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Influence of bone composition and apparent density on fracture toughness of the human femur and tibia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Increased bone formation in osteocalcin-deficient mice.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Basic biomechanical measurements of bone: a tutorial

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Effect of osteocalcin deficiency on the nanomechanics and chemistry of mouse bones.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Bone osteonal tissues by Raman spectral mapping: orientation-composition.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

The effect of gamma radiation sterilization on the fatigue crack propagation resistance of human cortical bone.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Effect of aging on the toughness of human cortical bone: evaluation by R-curves

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Automated method for subtraction of fluorescence from biological Raman spectra.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Effects of three different preservation methods on the mechanical properties of human and bovine cortical bone

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992706

Fracture toughness and work of fracture of hydrated, dehydrated, and ashed bovine bone

16 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24509412

12 December 2020

Effects of differences in mineralization on the mechanical properties of bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/24509412

12 December 2020

The role of collagen in the declining mechanical properties of aging human cortical bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/24509412

12 December 2020

Hierarchical relationship between bone traits and mechanical properties in inbred mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24509412

12 December 2020

Characterization of Osf1, an osteoblast-specific transcription factor binding to a critical cis-acting element in the mouse Osteocalcin promoters

1 reference

https://pubmed.ncbi.nlm.nih.gov/24509412

12 December 2020

Changes in the Stiffness, Strength, and Toughness of Human Cortical Bone With Age

1 reference

https://pubmed.ncbi.nlm.nih.gov/24509412

12 December 2020

The role of collagen in determining bone mechanical properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/24509412

12 December 2020

Aging of bone tissue: mechanical properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/24509412

12 December 2020

Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin

1 reference

https://pubmed.ncbi.nlm.nih.gov/24509412

12 December 2020

Bone brittleness varies with genetic background in A/J and C57BL/6J inbred mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24509412

12 December 2020

Twisted plywood architecture of collagen fibrils in human compact bone osteons

1 reference

https://pubmed.ncbi.nlm.nih.gov/24509412

12 December 2020

Effects of ionizing radiation on the mechanical properties of human bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/24509412

12 December 2020

10.1016/J.BONE.2014.01.021

Identifiers

DOI

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7 March 2020

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7 March 2020

PubMed publication ID

24509412

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