EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation (Q34963463)

5 August 2017

title

EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation (English)

1 reference

Leticia Quintanilla-Martínez de Fend

5 August 2017

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11

Leticia Quintanilla-Martinez

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Carsten Müller-Tidow

14

Carsten Müller-Tidow

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Martin S. Staege

Martin S Staege

13

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Heinrich Kovar

Heinrich Kovar

12

0 references

Marc Hotfilder

7

Marc Hotfilder

1 reference

5 August 2017

Günther H S Richter

1

1 reference

5 August 2017

Stephanie Plehm

2

1 reference

5 August 2017

Annette Fasan

3

1 reference

5 August 2017

Sabine Rössler

4

1 reference

5 August 2017

Rebekka Unland

5

1 reference

5 August 2017

Idriss M Bennani-Baiti

6

1 reference

5 August 2017

Diana Löwel

8

1 reference

5 August 2017

Irene von Luettichau

9

1 reference

5 August 2017

Ilona Mossbrugger

10

1 reference

5 August 2017

Stefan Burdach

15

1 reference

5 August 2017

language of work or name

English

0 references

publication date

16 March 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

published in

1 reference

5 August 2017

volume

106

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5 August 2017

issue

13

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5 August 2017

page(s)

5324-5329

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The Eukaryotic Genome as an RNA Machine

5 August 2017

cites work

1 reference

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8 July 2018

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Inducible expression of chimeric EWS/ETS proteins confers Ewing's family tumor-like phenotypes to human mesenchymal progenitor cells

8 July 2018

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Chromatin modifications induced by PML-RARalpha repress critical targets in leukemogenesis as analyzed by ChIP-Chip

8 July 2018

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DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2.

8 July 2018

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Mesenchymal stem cell features of Ewing tumors

8 July 2018

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A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

8 July 2018

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8 July 2018

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Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

8 July 2018

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8 July 2018

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Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells

8 July 2018

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Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

8 July 2018

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The Polycomb group protein EZH2 directly controls DNA methylation

8 July 2018

1 reference

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Development of Ewing's sarcoma from primary bone marrow-derived mesenchymal progenitor cells

8 July 2018

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The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

8 July 2018

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Milieu-adopted in vitro and in vivo differentiation of mesenchymal tissues derived from different adult human CD34-negative progenitor cell clones

8 July 2018

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EWS-FLI1 fusion protein up-regulates critical genes in neural crest development and is responsible for the observed phenotype of Ewing's family of tumors

8 July 2018

1 reference

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DNA microarrays reveal relationship of Ewing family tumors to both endothelial and fetal neural crest-derived cells and define novel targets

8 July 2018

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The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation

8 July 2018

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8 July 2018

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EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

8 July 2018

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EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

8 July 2018

1 reference

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Small interfering RNAs expressed from a Pol III promoter suppress the EWS/Fli-1 transcript in an Ewing sarcoma cell line

8 July 2018

1 reference

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The polycomb group protein EZH2 is involved in progression of prostate cancer

8 July 2018

1 reference

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The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts

8 July 2018

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Genesis: cluster analysis of microarray data

8 July 2018

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The COOH-terminal domain of FLI-1 is necessary for full tumorigenesis and transcriptional modulation by EWS/FLI-1.

8 July 2018

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Significance analysis of microarrays applied to the ionizing radiation response

8 July 2018

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Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation

8 July 2018

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Cluster analysis and display of genome-wide expression patterns

8 July 2018

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B cells inhibit induction of T cell-dependent tumor immunity.

8 July 2018

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Molecular cloning and primary structure of human glial fibrillary acidic protein

8 July 2018

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Isolation of a stem cell for neurons and glia from the mammalian neural crest

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656557

Expression of the EWS/FLI-1 oncogene in murine primary bone-derived cells Results in EWS/FLI-1-dependent, ewing sarcoma-like tumors

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0810759106

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0810759106

EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0810759106

Matrix metalloproteinase-12 expression correlates with local recurrence and metastatic disease in non-small cell lung cancer patients

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19289832

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Malignant peripheral neuroectodermal tumours of childhood and adolescence

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19289832

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0810759106

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference