Emerging roles of PPARs in inflammation and immunity (Q34931884)

5 August 2017

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title

Emerging roles of PPARs in inflammation and immunity (English)

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5 August 2017

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Raymond A Daynes

1

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5 August 2017

Dallas C Jones

series ordinal

2

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5 August 2017

publication date

1 October 2002

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Nature Reviews Immunology

5 August 2017

published in

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5 August 2017

volume

2

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5 August 2017

issue

10

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5 August 2017

page(s)

748-759

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Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages

5 August 2017

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Nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) is expressed in resting murine lymphocytes. The PPARalpha in T and B lymphocytes is both transactivation and transrepression competent

31 March 2020

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Peroxisome proliferator-activated receptor gamma activators affect the maturation of human monocyte-derived dendritic cells

31 March 2020

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The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis

31 March 2020

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Peroxisome proliferator-activated receptor-gamma haploinsufficiency enhances B cell proliferative responses and exacerbates experimentally induced arthritis

31 March 2020

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Prostaglandin and PPAR control of immune cell function

31 March 2020

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Peroxisome proliferator activator receptor-gamma agonists and 15-deoxy-Delta(12,14)(12,14)-PGJ(2) induce apoptosis in normal and malignant B-lineage cells

31 March 2020

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Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

31 March 2020

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Central role of peroxisome proliferator-activated receptors in the actions of peroxisome proliferators

31 March 2020

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Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

31 March 2020

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The peroxisome proliferator-activated receptor interacts with the retinoid X receptor in vivo

31 March 2020

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The mouse peroxisome proliferator activated receptor recognizes a response element in the 5' flanking sequence of the rat acyl CoA oxidase gene

31 March 2020

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Peroxisome proliferator-activated receptors: finding the orphan a home

31 March 2020

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Polarity and specific sequence requirements of peroxisome proliferator-activated receptor (PPAR)/retinoid X receptor heterodimer binding to DNA. A functional analysis of the malic enzyme gene PPAR response element

31 March 2020

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Stoichiometric and steric principles governing repression by nuclear hormone receptors

31 March 2020

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Histone deacetylase activity is required for full transcriptional repression by mSin3A

31 March 2020

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Identification of nuclear receptor corepressor as a peroxisome proliferator-activated receptor alpha interacting protein

31 March 2020

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The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling

31 March 2020

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Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors

31 March 2020

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p300 functions as a coactivator for the peroxisome proliferator-activated receptor alpha

31 March 2020

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Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor

31 March 2020

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The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion

31 March 2020

1 reference

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Molecular recognition of fatty acids by peroxisome proliferator-activated receptors

31 March 2020

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Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor

31 March 2020

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A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

31 March 2020

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15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes

31 March 2020

1 reference

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Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

31 March 2020

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Autoregulation of the human liver X receptor alpha promoter

31 March 2020

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Activation of PPARdelta alters lipid metabolism in db/db mice.

31 March 2020

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A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport

31 March 2020

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The peroxisome proliferator-activated receptor delta promotes lipid accumulation in human macrophages

31 March 2020

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Peroxisome proliferator-activated receptors in inflammation control

31 March 2020

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Peroxisome Proliferator-activated Receptor α Activation Modulates Cellular Redox Status, Represses Nuclear Factor-κB Signaling, and Reduces Inflammatory Cytokine Production in Aging

31 March 2020

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The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

31 March 2020

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Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene

31 March 2020

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Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

31 March 2020

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Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway

31 March 2020

1 reference

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Induction of IκBα Expression as a Mechanism Contributing to the Anti-inflammatory Activities of Peroxisome Proliferator-activated Receptor-α Activators

31 March 2020

1 reference

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Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies

31 March 2020

1 reference

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Critical roles of PPAR beta/delta in keratinocyte response to inflammation

31 March 2020

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The PPARalpha-leukotriene B4 pathway to inflammation control.

31 March 2020

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Immune senescence and adrenal steroids: immune dysregulation and the action of dehydroepiandrosterone (DHEA) in old animals

31 March 2020

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Regulation of gene expression by dietary fat.

31 March 2020

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Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators

31 March 2020

1 reference

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PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines

31 March 2020

1 reference

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Activators of peroxisome proliferator-activated receptors protect human skin from ultraviolet-B-light-induced inflammation

31 March 2020

1 reference

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Regulation of beta-amyloid stimulated proinflammatory responses by peroxisome proliferator-activated receptor alpha

31 March 2020

1 reference

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Activation of peroxisome proliferator-activated receptor gamma suppresses nuclear factor kappa B-mediated apoptosis induced by Helicobacter pylori in gastric epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI912

The PPARs: from orphan receptors to drug discovery

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI912

PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI912

Inhibition of IkappaB kinase and IkappaB phosphorylation by 15-deoxy-Delta(12,14)-prostaglandin J(2) in activated murine macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI912

15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI912

PPARalpha and PPARdelta activators inhibit cytokine-induced nuclear translocation of NF-kappaB and expression of VCAM-1 in EAhy926 endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI912

Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI912

Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI912

An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells

31 March 2020

1 reference

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Keratinocyte differentiation in hyperproliferative epidermis: topical application of PPARalpha activators restores tissue homeostasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI912

Helicobacter pylori-mediated transcriptional regulation of the human beta-defensin 2 gene requires NF-kappaB.

31 March 2020

1 reference

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Peroxisome proliferator-activated receptor gamma-retinoid X receptor agonists increase CD36-dependent phagocytosis of Plasmodium falciparum-parasitized erythrocytes and decrease malaria-induced TNF-alpha secretion by monocytes/macrophages

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRI912

PPARalpha agonists reduce 11beta-hydroxysteroid dehydrogenase type 1 in the liver.

31 March 2020

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Peroxisome proliferator-activated receptor-gamma ligands inhibit adipocyte 11beta -hydroxysteroid dehydrogenase type 1 expression and activity

31 March 2020

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Lack of tissue glucocorticoid reactivation in 11beta -hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments

31 March 2020

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Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11beta-hydroxysteroid dehydrogenase type 1 null mice

31 March 2020

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Pathophysiology of modulation of local glucocorticoid levels by 11beta-hydroxysteroid dehydrogenases

31 March 2020

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Dendritic cell development and maturation.

31 March 2020

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Antigen processing for amateurs and professionals

31 March 2020

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Peroxisome proliferator-activated receptor γ activators inhibit interleukin-12 production in murine dendritic cells

31 March 2020

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Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT.

31 March 2020

1 reference

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Inhibition of the transcription factors AP-1 and NF-kappaB in CD4 T cells by peroxisome proliferator-activated receptor gamma ligands

31 March 2020

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Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors

31 March 2020

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The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses

31 March 2020

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15-deoxy-Delta 12,14-PGJ2 induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway

31 March 2020

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Human B lymphocytes and B lymphomas express PPAR-gamma and are killed by PPAR-gamma agonists

31 March 2020

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Interleukin (IL)-4 indirectly suppresses IL-2 production by human T lymphocytes via peroxisome proliferator-activated receptor gamma activated by macrophage-derived 12/15-lipoxygenase ligands

31 March 2020

1 reference

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Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase

31 March 2020

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Gene microarrays reveal extensive differential gene expression in both CD4(+) and CD8(+) type 1 and type 2 T cells

31 March 2020

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A novel transcription factor, T-bet, directs Th1 lineage commitment

31 March 2020

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Dehydroepiandrosterone in systemic lupus erythematosus

31 March 2020

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Prevention of autoantibody formation and prolonged survival in New Zealand black/New Zealand white F1 mice fed dehydroisoandrosterone

31 March 2020

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Prostaglandins and essential fatty acids in regulation of autoimmunity and development of antibodies to DNA in NZB x NZW F1 mice

31 March 2020

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Androstenediol and dehydroepiandrosterone protect mice against lethal bacterial infections and lipopolysaccharide toxicity

31 March 2020

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Effects of dehydroepiandrosterone in immunosuppressed adult mice infected with Cryptosporidium parvum.

31 March 2020

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Dehydroepiandrosterone (DHEA) treatment reverses the impaired immune response of old mice to influenza vaccination and protects from influenza infection

31 March 2020

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Androstenediol regulates systemic resistance against lethal infections in mice

31 March 2020

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Androstenediol regulates systemic resistance against lethal infections in mice

31 March 2020

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What happened to drug trials in ulcerative colitis? Problems, PPARs, placebos, and (possible) progress

31 March 2020

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Peroxisome proliferator-activated receptor ligands as antiatherogenic agents: panacea or another Pandora's box?

31 March 2020

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Prostaglandins and leukotrienes: advances in eicosanoid biology

31 March 2020

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Association with Ets-1 causes ligand- and AF2-independent activation of nuclear receptors

31 March 2020

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Gadd45 family proteins are coactivators of nuclear hormone receptors

31 March 2020

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The role of peroxisome proliferator activated receptor alpha in peroxisome proliferation, physiological homeostasis, and chemical carcinogenesis

31 March 2020

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inferred from DOI database lookup

7 January 2021

based on heuristic

Characterization of a response element for peroxisomal proliferator activated receptor (PPRE) in human muscle-type carnitine palmitoyltransferase I.

1 reference

https://api.crossref.org/works/10.1038%2FNRI912

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI912

1 reference

5 August 2017

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