Vitamin D: direct effects of vitamin D metabolites on bone: lessons from genetically modified mice (Q34660221)

3 August 2017

1 reference

title

Vitamin D: direct effects of vitamin D metabolites on bone: lessons from genetically modified mice (English)

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3 August 2017

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1

John A Eisman

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3 August 2017

2

Roger Bouillon

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3 August 2017

publication date

5 February 2014

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3 August 2017

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3 August 2017

volume

3

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3 August 2017

page(s)

499

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3 August 2017

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Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization.

7 July 2018

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High dose 1,25(OH)2D3 inhibits osteoblast mineralization in vitro

7 July 2018

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7 July 2018

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Notch regulation of bone development and remodeling and related skeletal disorders

7 July 2018

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The role of vitamin D in paediatric bone health

7 July 2018

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Calcemic actions of vitamin D: effects on the intestine, kidney and bone

7 July 2018

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Vitamin D metabolism, cartilage and bone fracture repair

7 July 2018

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Intestinal vitamin D receptor is required for normal calcium and bone metabolism in mice

7 July 2018

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The direct role of vitamin D on bone homeostasis

7 July 2018

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7 July 2018

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Effects of continuous activation of vitamin D and Wnt response pathways on osteoblastic proliferation and differentiation

7 July 2018

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Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts

7 July 2018

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1,25-Dihydroxyvitamin D3 regulates the expression of low-density lipoprotein receptor-related protein 5 via deoxyribonucleic acid sequence elements located downstream of the start site of transcription

7 July 2018

1 reference

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Osteoblasts lacking the vitamin D receptor display enhanced osteogenic potential in vitro

7 July 2018

1 reference

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1Alpha,25-dihydroxyvitamin D3 promotes vascularization of the chondro-osseous junction by stimulating expression of vascular endothelial growth factor and matrix metalloproteinase 9.

7 July 2018

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Duodenal calcium absorption in vitamin D receptor-knockout mice: functional and molecular aspects

7 July 2018

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Targeted ablation of the 25-hydroxyvitamin D 1alpha -hydroxylase enzyme: evidence for skeletal, reproductive, and immune dysfunction

7 July 2018

1 reference

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Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia

7 July 2018

1 reference

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Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning

7 July 2018

1 reference

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1,25-dihydroxyvitamin D-responsive element and glucocorticoid repression in the osteocalcin gene

7 July 2018

1 reference

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The vitamin D-responsive element in the rat bone Gla protein gene is an imperfect direct repeat that cooperates with other cis-elements in 1,25-dihydroxyvitamin D3- mediated transcriptional activation.

7 July 2018

1 reference

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Maternal hypervitaminosis D reduces fetal bone mass and mineral acquisition and leads to neonatal lethality

7 July 2018

1 reference

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Chondrocyte-specific modulation of Cyp27b1 expression supports a role for local synthesis of 1,25-dihydroxyvitamin D3 in growth plate development.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944130

Direct action of 1,25-dihydroxyvitamin D on bone: VDRKO bone shows excessive bone formation in normal mineral condition

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944130

Inactivation of the 25-hydroxyvitamin D 1alpha-hydroxylase and vitamin D receptor demonstrates independent and interdependent effects of calcium and vitamin D on skeletal and mineral homeostasis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944130

Mouse alpha1(I)-collagen promoter is the best known promoter to drive efficient Cre recombinase expression in osteoblast

26 October 2018

1 reference

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Deletion of deoxyribonucleic acid binding domain of the vitamin D receptor abrogates genomic and nongenomic functions of vitamin D.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944130

Targeted inactivation of the 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944130

Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: formal histomorphometric and biomechanical analyses

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944130

Vitamin D Action and Regulation of Bone Remodeling: Suppression of Osteoclastogenesis by the Mature Osteoblast

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944130

Human and Murine Osteocalcin Gene Expression: Conserved Tissue Restricted Expression and Divergent Responses to 1,25-Dihydroxyvitamin D3in Vivo

9 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944130

Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24605216

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Deficient mineralization of intramembranous bone in vitamin D-24-hydroxylase-ablated mice is due to elevated 1,25-dihydroxyvitamin D and not to the absence of 24,25-dihydroxyvitamin D

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24605216

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increased formation and decreased resorption of bone in mice with elevated vitamin D receptor in mature cells of the osteoblastic lineage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24605216

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/BONEKEY.2013.233

1 reference

3 August 2017

1 reference

3 August 2017

1 reference