Towards a blood-stage vaccine for malaria: are we following all the leads? (Q34572160)

3 August 2017

1 reference

title

Towards a blood-stage vaccine for malaria: are we following all the leads? (English)

1 reference

3 August 2017

0 references

1 reference

1 reference

1

Good MF

1 reference

3 August 2017

publication date

1 November 2001

1 reference

Nature Reviews Immunology

3 August 2017

published in

1 reference

3 August 2017

volume

1

1 reference

3 August 2017

issue

2

1 reference

3 August 2017

page(s)

117-125

1 reference

The real difficulties for malaria sporozoite vaccine development: nonresponsiveness and antigenic variation

3 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2F35100540

'Original antigenic sin', T cell memory, and malaria sporozoite immunity: an hypothesis for immune evasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Selective recognition of malaria antigens by human serum antibodies is not genetically determined but demonstrates some features of clonal imprinting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Immune effector mechanisms in malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

The complexity of protective immunity against liver-stage malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Transmission-blocking vaccines: uses and current status of development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Age-dependent characteristics of protection v. susceptibility to Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Antigens induced on erythrocytes by P. falciparum: expression of diverse and conserved determinants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Plasmodium falciparum: the human agglutinating antibody response to the infected red cell surface is predominantly variant specific

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Mortality and morbidity from malaria among children in a rural area of The Gambia, West Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Antigenic variation in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of plasmodium falciparum-infected erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

New multi-determinant strategy for a group A streptococcal vaccine designed for the Australian Aboriginal population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Dominance and crypticity of T cell antigenic determinants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Epitope repertoire of human CD4+ lines propagated with tetanus toxoid or with synthetic tetanus toxin sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

The surface variant antigens of Plasmodium falciparum contain cross-reactive epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Pathways and strategies for developing a malaria blood-stage vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Vaccination trials in rhesus monkeys with a minor, invariant, Plasmodium knowlesi 66 kD merozoite antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Immunogenicity and efficacy in aotus monkeys of four recombinant Plasmodium falciparum vaccines in multiple adjuvant formulations based on the 19-kilodalton C terminus of merozoite surface protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Vaccine efficacy of recombinant Plasmodium falciparum merozoite surface protein 1 in malaria-naive, -exposed, and/or -rechallenged Aotus vociferans monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

The crystal structure of C-terminal merozoite surface protein 1 at 1.8 A resolution, a highly protective malaria vaccine candidate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Effect of vaccination with 3 recombinant asexual-stage malaria antigens on initial growth rates of Plasmodium falciparum in non-immune volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Safety and immunogenicity of a three-component blood-stage malaria vaccine in adults living in an endemic area of Papua New Guinea

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Randomised trial of efficacy of SPf66 vaccine against Plasmodium falciparum malaria in children in southern Tanzania.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Efficacy trial of malaria vaccine SPf66 in Gambian infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Randomised double-blind placebo-controlled trial of SPf66 malaria vaccine in children in northwestern Thailand. Shoklo SPf66 Malaria Vaccine Trial Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

An efficacy trial of the malaria vaccine SPf66 in Gambian infants--second year of follow-up.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Serological responses of Gambian children to immunization with the malaria vaccine SPf66.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Antibodies that inhibit malaria merozoite surface protein-1 processing and erythrocyte invasion are blocked by naturally acquired human antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Inhibitory and blocking monoclonal antibody epitopes on merozoite surface protein 1 of the malaria parasite Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

A principal target of human immunity to malaria identified by molecular population genetic and immunological analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Analysis of sequence diversity in the Plasmodium falciparum merozoite surface protein-1 (MSP-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Proteolytic processing of the Plasmodium falciparum merozoite surface protein-1 produces a membrane-bound fragment containing two epidermal growth factor-like domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Intranasal immunization with yeast-expressed 19 kD carboxyl-terminal fragment of Plasmodium yoelii merozoite surface protein-1 (yMSP119) induces protective immunity to blood stage malaria infection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Immunoglobulin G3 antibodies specific for the 19-kilodalton carboxyl-terminal fragment of Plasmodium yoelii merozoite surface protein 1 transfer protection to mice deficient in Fc-gammaRI receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Cytophilic immunoglobulin responses to Plasmodium falciparum glutamate-rich protein are correlated with protection against clinical malaria in Dielmo, Senegal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Mechanisms of defense against P. falciparum asexual blood stages in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Definition of T cell epitopes within the 19 kDa carboxylterminal fragment of Plasmodium yoelii merozoite surface protein 1 (MSP1(19)) and their role in immunity to malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Naturally acquired cellular and humoral immune responses to the major merozoite surface antigen (PfMSP1) of Plasmodium falciparum are associated with reduced malaria morbidity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Human antibodies to the 19kDa C-terminal fragment of Plasmodium falciparum merozoite surface protein 1 inhibit parasite growth in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Antibodies to blood stage antigens of Plasmodium falciparum in rural Gambians and their relation to protection against infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Antibodies against merozoite surface protein (MSP)-1(19) are a major component of the invasion-inhibitory response in individuals immune to malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS,S Malaria Vaccine Evaluation Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Long-term efficacy and immune responses following immunization with the RTS,S malaria vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Strategies for improving responses to DNA vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Immunogenicity and in vitro protective efficacy of a recombinant multistage Plasmodium falciparum candidate vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Development, expression, and murine testing of a multistage Plasmodium falciparum malaria vaccine candidate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Malaria vaccine development: current status

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

The role of TH1 and TH2 cells in a rodent malaria infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Prolonged Th1-like response generated by a Plasmodium yoelii-specific T cell clone allows complete clearance of infection in reconstituted mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Protection of rats against malaria by a transplanted immune spleen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Central role of endogenous gamma interferon in protective immunity against blood-stage Plasmodium chabaudi AS infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Interferon-gamma responses are associated with resistance to reinfection with Plasmodium falciparum in young African children

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Plasmodium falciparum-infected erythrocytes modulate the maturation of dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Relation between falciparum malaria and HIV seropositivity in Ndola, Zambia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

The clinical and parasitological presentation of Plasmodium falciparum malaria in Uganda is unaffected by HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Human immunodeficiency virus and malaria in a representative sample of childbearing women in Kigali, Rwanda

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Plasmodium Falciparum malaria and perinatally acquired human immunodeficiency virus type 1 infection in Kinshasa, Zaire. A prospective, longitudinal cohort study of 587 children

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Incidence of malaria and efficacy of oral quinine in patients recently infected with human immunodeficiency virus in Kinshasa, Zaire

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Effects of malaria infection in human immunodeficiency virus type 1-infected Ugandan children

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Is there an interaction between human immunodeficiency virus and Plasmodium falciparum?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Effect of HIV-1 and increasing immunosuppression on malaria parasitaemia and clinical episodes in adults in rural Uganda: a cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

HIV-1 infection and malaria parasitaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Maternal antibodies block malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

The adhesion of Plasmodium falciparum-infected erythrocytes to chondroitin sulfate A is mediated by P. falciparum erythrocyte membrane protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Plasmodium falciparum domain mediating adhesion to chondroitin sulfate A: a receptor for human placental infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Deletion of Plasmodium berghei-specific CD4+ T cells adoptively transferred into recipient mice after challenge with homologous parasite

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Malaria parasite-specific Th1-like T cells simultaneously reduce parasitemia and promote disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

On some Peculiar Pigmented Cells Found in Two Mosquitos Fed on Malarial Blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Sidelights on malaria in man obtained by subinoculation experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Expression of Plasmodium falciparum blood-stage antigens in Escherichia coli: detection with antibodies from immune humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

Cloning and expression in E. coli of the malarial sporozoite surface antigen gene from Plasmodium knowlesi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2F35100540

7 January 2021

Protective immunity induced in squirrel monkeys with recombinant apical membrane antigen-1 of Plasmodium fragile.

1 reference

https://api.crossref.org/works/10.1038%2F35100540

7 January 2021

Protective immune responses to apical membrane antigen 1 of Plasmodium chabaudi involve recognition of strain-specific epitopes

1 reference

https://api.crossref.org/works/10.1038%2F35100540

7 January 2021

Immunization against malaria with a recombinant protein.

1 reference

https://api.crossref.org/works/10.1038%2F35100540

7 January 2021

Protection against malaria in Aotus monkeys immunized with a recombinant blood-stage antigen fused to a universal T-cell epitope: correlation of serum gamma interferon levels with protection

1 reference

https://api.crossref.org/works/10.1038%2F35100540

7 January 2021

A longitudinal investigation of IgG and IgM antibody responses to the merozoite surface protein-1 19-kiloDalton domain of Plasmodium falciparum in pregnant women and infants: associations with febrile illness, parasitemia, and anemia.

1 reference

https://api.crossref.org/works/10.1038%2F35100540

7 January 2021

Antibody-independent immunity to reinfection malaria in B-cell-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2F35100540

7 January 2021

Plasmodium falciparum induces apoptosis in human mononuclear cells.

1 reference

https://api.crossref.org/works/10.1038%2F35100540

7 January 2021

Identifiers

DOI

10.1038/35100540

1 reference

Dimensions Publication ID

3 August 2017

1034156374

0 references

1 reference