How strong is the evidence that brain serotonin neurons are damaged in human users of ecstasy? (Q34558846)

3 August 2017

1 reference

title

How strong is the evidence that brain serotonin neurons are damaged in human users of ecstasy? (English)

1 reference

3 August 2017

0 references

Stephen J Kish

1

1 reference

3 August 2017

language of work or name

English

0 references

publication date

1 April 2002

1 reference

Pharmacology, Biochemistry and Behavior

3 August 2017

published in

1 reference

3 August 2017

volume

71

1 reference

3 August 2017

issue

4

1 reference

3 August 2017

page(s)

845-855

1 reference

Alpha-lipoic acid prevents 3,4-methylenedioxy-methamphetamine (MDMA)-induced neurotoxicity

3 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Neuroanatomic specificity and time course of alterations in rat brain serotonergic pathways induced by MDMA (3,4-methylenedioxymethamphetamine): assessment using quantitative autoradiography

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Neuropsychological deficits in abstinent cocaine abusers: preliminary findings after two weeks of abstinence.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Recreational use of 3,4-methylenedioxymethamphetamine (MDMA) or 'ecstasy': evidence for cognitive impairment

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Memory impairment in abstinent MDMA ("Ecstasy") users

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Dual serotonin (5-HT) projections to the nucleus accumbens core and shell: relation of the 5-HT transporter to amphetamine-induced neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Evaluation of serotonergic transporters using PET and [11C](+)McN-5652: assessment of methods

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Human brain serotonin synthesis capacity measured in vivo with alpha-[C-11]methyl-L-tryptophan

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ('ecstasy') and p-chloroamphetamine but not the degeneration following fenfluramine

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

The relative contributions of ecstasy and cannabis to cognitive impairment

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Elevated hypothalamic/midbrain serotonin (monoamine) transporter availability in depressive drug-naive children and adolescents.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Cognitive impairment among methadone maintenance patients

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

1 reference

7 January 2021

Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Impaired cognitive performance in drug free users of recreational ecstasy (MDMA)

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Deconstructing Ecstasy: The Politics Of Mdma Research

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Carrier-mediated release of serotonin by 3,4-methylenedioxymethamphetamine: implications for serotonin-dopamine interactions.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Allelic Variation of Human Serotonin Transporter Gene Expression

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Serotonin transporters in ecstasy users

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

A relationship between serotonin transporter genotype and in vivo protein expression and alcohol neurotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

5-hydroxytryptamine uptake blockers attenuate the 5-hydroxytryptamine-releasing effect of 3,4-methylenedioxymethamphetamine and related agents

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Positron emission tomography findings in heavy users of MDMA.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Imaging the serotonin transporter with positron emission tomography: initial human studies with [11C]DAPP and [11C]DASB.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Direct effects of 3,4-methylenedioxymethamphetamine (MDMA) on serotonin or dopamine release and uptake in the caudate putamen, nucleus accumbens, substantia nigra pars reticulata, and the dorsal raphé nucleus slices

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Elevated central serotonin transporter binding availability in acutely abstinent cocaine-dependent patients

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Overexpression of human copper/zinc superoxide dismutase in transgenic mice attenuates oxidative stress caused by methylenedioxymethamphetamine (Ecstasy).

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

The acute effects of amphetamine derivatives on extracellular serotonin and dopamine levels in rat nucleus accumbens

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Striatal serotonin is depleted in brain of a human MDMA (Ecstasy) user

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Striatal dopaminergic and serotonergic markers in human heroin users

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Chronic 3,4-methylenedioxymethamphetamine (MDMA) use: effects on mood and neuropsychological function?

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Toxic effect of MDMA on brain serotonin neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Imaging of serotonin and dopamine transporters in the living human brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Dopamine and serotonin transporters in patients with schizophrenia: an imaging study with [(123)I]beta-CIT.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Isolation of a cDNA encoding the human brain serotonin transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Acute psychological and physiological effects of MDMA ("Ecstasy") after haloperidol pretreatment in healthy humans

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Acute psychological effects of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") are attenuated by the serotonin uptake inhibitor citalopram

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Psychological and physiological effects of MDMA ("Ecstasy") after pretreatment with the 5-HT(2) antagonist ketanserin in healthy humans

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Gender differences in the subjective effects of MDMA.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission computed tomography

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Serotonin transporters upregulate with chronic cocaine use.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Caveat emptor: editors beware

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Positron emission tomographic evidence of toxic effect of MDMA ("Ecstasy") on brain serotonin neurons in human beings

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35,428.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Cognitive performance in (+/-) 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") users: a controlled study

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Estradiol-17 beta increases serotonin transporter (SERT) mRNA levels and the density of SERT-binding sites in female rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Autoradiographic analyses of the effects of estradiol benzoate on [3H]paroxetine binding in the cerebral cortex and dorsal hippocampus of gonadectomized male and female rats

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

5-HT system and cognition

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Memory deficits associated with recreational use of "ecstasy" (MDMA).

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Ecstasy (MDMA): a review of its possible persistent psychological effects

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Effects of certain hallucinogenic amphetamine analogues on the release of [3H]serotonin from rat brain synaptosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Validation of a less-invasive method for measurement of serotonin synthesis rate with alpha-[11C]methyl-tryptophan

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Profiles of cognitive dysfunction in chronic amphetamine and heroin abusers.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

MDMA (Ecstasy) precipitation of panic disorder

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Ecstasy (MDMA) effects upon mood and cognition: before, during and after a Saturday night dance

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Cognitive performance in recreational users of MDMA of 'ecstasy': evidence for memory deficits

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Regulation of serotonin re-uptake transporter mRNA expression by ovarian steroids in rhesus macaques

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

?-CIT SPECT demonstrates blockade of 5HT-uptake sites by citalopram in the human brain in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Serotonin and the sleep/wake cycle: special emphasis on microdialysis studies

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Upregulation of imipramine binding and serotonin uptake by estradiol in female rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Memory disturbances in "Ecstasy" users are correlated with an altered brain serotonin neurotransmission

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Effects of dose, sex, and long-term abstention from use on toxic effects of MDMA (ecstasy) on brain serotonin neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Cortical serotonin transporter density and verbal memory in individuals who stopped using 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy"): preliminary findings

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Cognitive performance amongst recreational users of "ecstasy".

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

The molecular mechanism of "ecstasy" [3,4-methylenedioxy-methamphetamine (MDMA)]: serotonin transporters are targets for MDMA-induced serotonin release

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

MDMA ('ecstasy') consumption in the context of polydrug abuse: a report on 150 patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Reduced in vivo binding to the serotonin transporter in the cerebral cortex of MDMA ('ecstasy') users

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Involvement of the serotonin transporter in the formation of hydroxyl radicals induced by 3,4-methylenedioxymethamphetamine

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

The suitability of [11C]-alpha-methyl-L-tryptophan as a tracer for serotonin synthesis: studies with dual administration of [11C] and [14C] labeled tracer

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Cognitive impairment in individuals currently using methamphetamine

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Neuropsychological deficits in withdrawn cocaine-dependent males

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Recreational MDMA use in Sydney: a profile of 'Ecstacy' users and their experiences with the drug

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Imaging of the serotonergic system: interactions of neuroanatomical and functional abnormalities of depression

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Sex differences in [123I]beta-CIT SPECT measures of dopamine and serotonin transporter availability in healthy smokers and nonsmokers.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Immediate and long-term effects of 3,4-methylenedioxymethamphetamine on serotonin pathways in brain of rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Effects of tamoxifen on serotonin transporter and 5-hydroxytryptamine(2A) receptor binding sites and mRNA levels in the brain of ovariectomized rats with or without acute estradiol replacement.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Application of silver degeneration stains for neurotoxicity testing

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Positron emission tomography imaging of serotonin transporters in the human brain using [11C](+)McN5652

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Cognitive capacity in female adolescent substance abusers

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

In vivo visualization of serotonin transporters in the human brain during fluoxetine treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Anatomy of the serotonergic system

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Cognitive performance and serotonergic function in users of ecstasy.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Positron emission tomographic evidence for progression of human MPTP-induced dopaminergic lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Loss of dopamine transporters in methamphetamine abusers recovers with protracted abstinence.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Working memory deficits in current and previous users of MDMA ('ecstasy').

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

No evidence for in vivo regulation of midbrain serotonin transporter availability by serotonin transporter promoter gene polymorphism

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Heterogeneous subregional binding patterns of 3H-WIN 35,428 and 3H-GBR 12,935 are differentially regulated by chronic cocaine self-administration.

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Striatal dopamine nerve terminal markers in human, chronic methamphetamine users

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Striatal dopamine, dopamine transporter, and vesicular monoamine transporter in chronic cocaine users

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

N-tert-butyl-alpha-phenylnitrone protects against 3,4-methylenedioxymethamphetamine-induced depletion of serotonin in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Memory impairment in abstinent MDMA ("Ecstasy") users: a longitudinal investigation

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

Serotonin transporters are located on the axons beyond the synaptic junctions: anatomical and functional evidence

1 reference

https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900708-0

7 January 2021

10.1016/S0091-3057(01)00708-0

Identifiers

DOI

1 reference

3 August 2017

1 reference