Microtubule-stabilizing agents based on designed laulimalide analogues (Q34515802)

2 August 2017

title

Microtubule-stabilizing agents based on designed laulimalide analogues (English)

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Cacospongia mycofijiensis

2 August 2017

main subject

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Susan L Mooberry

1

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2 August 2017

Deborah A Randall-Hlubek

2

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2 August 2017

Rachel M Leal

3

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2 August 2017

Sayee G Hegde

4

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2 August 2017

Robert D Hubbard

5

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2 August 2017

Lei Zhang

6

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2 August 2017

Paul A Wender

7

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2 August 2017

language of work or name

English

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publication date

25 May 2004

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full work available at URL

2 August 2017

https://europepmc.org/articles/pmc423276?pdf=render

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19 March 2024

https://api.unpaywall.org/v2/10.1073/pnas.0402759101?email=unpaywall_01@example.com

published in

Proceedings of the National Academy of Sciences of the United States of America

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2 August 2017

volume

101

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2 August 2017

issue

23

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2 August 2017

page(s)

8803-8808

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https://api.unpaywall.org/v2/10.1073/pnas.0402759101?email=unpaywall_01@example.com

2 August 2017

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19 March 2024

access restriction status

open access

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inferred from online access status

cites work

Synthesis and biological evaluation of (-)-laulimalide analogues

1 reference

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Synthetic approaches to the microtubule stabilizing agent (-)-laulimalide.

7 July 2018

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Differential mitotic responses to microtubule-stabilizing and -destabilizing drugs

7 July 2018

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Structural basis for the interaction of tubulin with proteins and drugs that affect microtubule dynamics

7 July 2018

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A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

7 July 2018

1 reference

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Laulimalide and isolaulimalide, new paclitaxel-like microtubule-stabilizing agents.

7 July 2018

1 reference

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Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization

7 July 2018

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Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining

7 July 2018

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The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for activity.

7 July 2018

1 reference

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Macrocyclization via allyl transfer: total synthesis of laulimalide

21 January 2018

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Total synthesis of microtubule-stabilizing agent (-)-laulimalide

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0402759101

Total synthesis of (-)-laulimalide

21 January 2018

1 reference

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Asymmetric total synthesis of (-)-laulimalide: exploiting the asymmetric glycolate alkylation reaction

21 January 2018

1 reference

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Total synthesis of the microtubule stabilizing antitumor agent laulimalide and some nonnatural analogues: the power of Sharpless' asymmetric epoxidation.

21 January 2018

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Taccalonolides E and A: Plant-derived steroids with microtubule-stabilizing activity.

21 January 2018

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Total synthesis of the microtubule-stabilizing agent (-)-laulimalide

27 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/15161976

12 December 2020

A de Novo Enantioselective Total Synthesis of (−)-Laulimalide

1 reference

https://pubmed.ncbi.nlm.nih.gov/15161976

12 December 2020

An Intramolecular Case of Sharpless Kinetic Resolution: Total Synthesis of Laulimalide

1 reference

https://pubmed.ncbi.nlm.nih.gov/15161976

12 December 2020

Total Synthesis of (-)-Laulimalide

1 reference

https://pubmed.ncbi.nlm.nih.gov/15161976

12 December 2020

Identifiers

DOI

10.1073/PNAS.0402759101

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2 August 2017

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2 August 2017

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