The adenosine A3 receptor and its ligands (Q34483322)

2 August 2017

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title

The adenosine A3 receptor and its ligands (English)

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2 August 2017

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van Muijlwijk-Koezen JE

series ordinal

1

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2 August 2017

Timmerman H

series ordinal

2

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2 August 2017

Ijzerman AP

series ordinal

3

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2 August 2017

publication date

1 January 2001

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Progress in medicinal chemistry

2 August 2017

published in

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2 August 2017

volume

38

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2 August 2017

page(s)

61-113

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The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart

2 August 2017

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Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor

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Localization of the A3 adenosine receptor gene (ADORA3) to human chromosome 1p

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Cloning, characterisation and chromosomal assignment of the human adenosine A3 receptor (ADORA3) gene

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cDNA cloning and characterization of A3i, an alternatively spliced rat A3 adenosine receptor variant

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7 January 2021

Tissue distribution of adenosine receptor mRNAs in the rat.

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7 January 2021

Species-dependent hemodynamic effects of adenosine A3-receptor agonists IB-MECA and Cl-IB-MECA

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Binding affinity of adenosine receptor agonists and antagonists at human cloned A3 adenosine receptors

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Structure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonists

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Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.

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A novel class of adenosine A3 receptor ligands. 1. 3-(2-Pyridinyl)isoquinoline derivatives

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Expression and function of adenosine receptors in the chinchilla cochlea

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Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are selective for the human A3 receptor subtype

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Differential interaction with and regulation of multiple G-proteins by the rat A3 adenosine receptor

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Agonist-dependent phosphorylation and desensitization of the rat A3 adenosine receptor. Evidence for a G-protein-coupled receptor kinase-mediated mechanism

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7 January 2021

Induction of apoptosis in HL-60 human promyelocytic leukemia cells by adenosine A(3) receptor agonists.

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Induction of apoptosis in cardiac myocytes by an A3 adenosine receptor agonist

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A3 adenosine receptors regulate Cl- channels of nonpigmented ciliary epithelial cells

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Selective activation of adenosine A3 receptors with N6-(3-chlorobenzyl)-5'-N-methylcarboxamidoadenosine (CB-MECA) provides cardioprotection via KATP channel activation

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An A3-subtype adenosine receptor is highly expressed in rat vascular smooth muscle cells: its role in attenuating adenosine-induced increase in cAMP.

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Synthesis and biological activity of a new series of N6-arylcarbamoyl, 2-(Ar)alkynyl-N6-arylcarbamoyl, and N6-carboxamido derivatives of adenosine-5'-N-ethyluronamide as A1 and A3 adenosine receptor agonists

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7 January 2021

Adenosine A3 receptor stimulation and cerebral ischemia

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7 January 2021

The effects of adenosine A3 receptor stimulation on seizures in mice

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7 January 2021

Adenosine A3 receptor agonist-induced neurotoxicity in rat cerebellar granule neurons

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7 January 2021

Adenosine A3 receptors potentiate hippocampal calcium current by a PKA-dependent/PKC-independent pathway

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7 January 2021

Activation of hippocampal adenosine A3 receptors produces a desensitization of A1 receptor-mediated responses in rat hippocampus.

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7 January 2021

A role for central A3-adenosine receptors. Mediation of behavioral depressant effects

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7 January 2021

Protein kinase C and A3 adenosine receptor activation inhibit presynaptic metabotropic glutamate receptor (mGluR) function and uncouple mGluRs from GTP-binding proteins.

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7 January 2021

The A3 adenosine receptor mediates cell spreading, reorganization of actin cytoskeleton, and distribution of Bcl-XL: studies in human astroglioma cells.

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7 January 2021

A novel cardioprotective function of adenosine A1 and A3 receptors during prolonged simulated ischemia

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7 January 2021

Selective adenosine A3 receptor stimulation reduces ischemic myocardial injury in the rabbit heart

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7 January 2021

Direct preconditioning of cultured chick ventricular myocytes. Novel functions of cardiac adenosine A2a and A3 receptors

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7 January 2021

Evidence that the adenosine A3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart

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7 January 2021

Evidence for a role for both the adenosine A1 and A3 receptors in protection of isolated human atrial muscle against simulated ischaemia

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7 January 2021

A(3) adenosine receptor activation attenuates neutrophil function and neutrophil-mediated reperfusion injury

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7 January 2021

A physiological role of the adenosine A3 receptor: sustained cardioprotection

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7 January 2021

Adenosine A3 receptors mediate hypotension in the angiotensin II-supported circulation of the pithed rat.

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7 January 2021

A role for mast cells in adenosine A3 receptor‐mediated hypotension in the rat

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7 January 2021

Mast cell degranulation following adenosine A3 receptor activation in rats

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7 January 2021

Hemodynamic effects and histamine release elicited by the selective adenosine A3 receptor agonist 2-Cl-IB-MECA in conscious rats

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7 January 2021

The role of A3 adenosine receptors in central regulation of arterial blood pressure.

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7 January 2021

Adenosine-induced vasoconstriction in vivo. Role of the mast cell and A3 adenosine receptor

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7 January 2021

Adenosine regulates tissue factor expression on endothelial cells.

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7 January 2021

Adenosine A3 receptor agonists protect HL-60 and U-937 cells from apoptosis induced by A3 antagonists

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7 January 2021

2-Chloroadenosine inhibits the MHC-unrestricted cytolytic activity of anti-CD3-activated killer cells: evidence for the involvement of a non-A1/A2 cell-surface adenosine receptor

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7 January 2021

Adenosine A3 receptors promote degranulation of rat mast cells both in vitro and in vivo

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7 January 2021

Activation of adenosine A3 receptors on macrophages inhibits tumor necrosis factor-alpha

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7 January 2021

Adenosine A3 receptor expression and function in eosinophils

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7 January 2021

Adenosine A3 receptor stimulation inhibits migration of human eosinophils

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7 January 2021

Suppression of macrophage inflammatory protein (MIP)-1alpha production and collagen-induced arthritis by adenosine receptor agonists

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An agonist of adenosine A3 receptors decreases interleukin-12 and interferon-gamma production and prevents lethality in endotoxemic mice

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7 January 2021

Inhibition of fMLP-triggered respiratory burst of human monocytes by adenosine: involvement of A3 adenosine receptor

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7 January 2021

Adenosine A3 receptor activation produces nociceptive behaviour and edema by release of histamine and 5-hydroxytryptamine

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7 January 2021

Adenosine receptor activation and nociception

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7 January 2021

A3 Adenosine Receptors: Protective vs. Damaging Effects Identified Using Novel Agonists and Antagonists

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7 January 2021

Adenosine and cerebral ischemia: therapeutic future or death of a brave concept?

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7 January 2021

Clinical effects of ischemic preconditioning

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7 January 2021

Endogenous adenosine inhibits platelet aggregation during myocardial ischemia in dogs

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7 January 2021

The effect of adenosine and its analogues on histamine release from mast cells

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7 January 2021

Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation

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7 January 2021

Adenosine A3 receptors in mast cells

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7 January 2021

The structure and function of A1 and A2B adenosine receptors

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7 January 2021

Inosine-induced vasoconstriction is mediated by histamine and thromboxane derived from mast cells

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7 January 2021

Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors

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7 January 2021

5'-N-substituted carboxamidoadenosines as agonists for adenosine receptors

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7 January 2021

Pharmacological characterization of novel A3 adenosine receptor-selective antagonists

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7 January 2021

Selective activation of A3 adenosine receptors with N6-(3-iodobenzyl)adenosine-5'-N-methyluronamide protects against myocardial stunning and infarction without hemodynamic changes in conscious rabbits

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7 January 2021

A selective agonist affinity label for A3 adenosine receptors

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7 January 2021

2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors

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7 January 2021

2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies

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7 January 2021

2-Substituted N-ethylcarboxamidoadenosine derivatives as high-affinity agonists at human A3 adenosine receptors

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7 January 2021

Novel N6-(substituted-phenylcarbamoyl)adenosine-5'-uronamides as potent agonists for A3 adenosine receptors

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7 January 2021

The synthesis of new adenosine A3 selective ligands containing bioisosteric isoxazoles

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7 January 2021

Selective ligands for rat A3 adenosine receptors: structure-activity relationships of 1,3-dialkylxanthine 7-riboside derivatives.

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7 January 2021

Activation and Desensitization of Rat A3-Adenosine Receptors by Selective Adenosine Derivatives and Xanthine-7-Ribosides

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7 January 2021

Molecular pharmacological aspects of histamine receptors

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7 January 2021

5'-substituted adenosine analogs as new high-affinity partial agonists for the adenosine A1 receptor

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7 January 2021

Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors

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7 January 2021

A SURVEY OF NONXANTHINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS.

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7 January 2021

Interactions of flavonoids and other phytochemicals with adenosine receptors

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7 January 2021

Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists

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7 January 2021

1,4-Dihydropyridine antagonist activities at the calcium channel: a quantitative structure-activity relationship approach.

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7 January 2021

Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors

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7 January 2021

4-Alkyl-1,4-dihydropyridines derivatives as specific PAF-acether antagonists

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7 January 2021

Discovery of alpha 1a-adrenergic receptor antagonists based on the L-type Ca2+ channel antagonist niguldipine

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7 January 2021

The nicotinic acetylcholine receptor of the bovine chromaffin cell, a new target for dihydropyridines

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7 January 2021

6-phenyl-1,4-dihydropyridine derivatives as potent and selective A3 adenosine receptor antagonists

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7 January 2021

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