Tsg101 is essential for cell growth, proliferation, and cell survival of embryonic and adult tissues (Q34462948)

2 August 2017

title

Tsg101 is essential for cell growth, proliferation, and cell survival of embryonic and adult tissues (English)

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2 August 2017

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Lothar Hennighausen

9

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author name string

Kay-Uwe Wagner

1

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2 August 2017

Andrea Krempler

2

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2 August 2017

Yongyue Qi

3

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2 August 2017

KyungRan Park

4

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2 August 2017

MaLinda D Henry

5

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2 August 2017

Aleata A Triplett

6

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2 August 2017

Gregory Riedlinger

7

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2 August 2017

Edmund B Rucker III

8

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2 August 2017

language of work or name

English

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publication date

1 January 2003

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Molecular and Cellular Biology

2 August 2017

published in

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2 August 2017

volume

23

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2 August 2017

issue

1

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2 August 2017

page(s)

150-162

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Targeted deletion of the Tsg101 gene results in cell cycle arrest at G1/S and p53-independent cell death

2 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Negative regulation of cell growth and differentiation by TSG101 through association with p21(Cip1/WAF1).

6 July 2018

1 reference

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Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity

6 July 2018

1 reference

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Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

A TSG101/MDM2 regulatory loop modulates MDM2 degradation and MDM2/p53 feedback control

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Genomic architecture and transcriptional activation of the mouse and human tumor susceptibility gene TSG101: common types of shorter transcripts are true alternative splice variants

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Perturbation of TSG101 protein affects cell cycle progression.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

A putative tumor suppressor, TSG101, acts as a transcriptional suppressor through its coiled-coil domain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Cell cycle-dependent subcellular localization of the TSG101 protein and mitotic and nuclear abnormalities associated with TSG101 deficiency

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Aberrant splicing of the TSG101 and FHIT genes occurs frequently in multiple malignancies and in normal tissues and mimics alterations previously described in tumours

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Cre-mediated gene deletion in the mammary gland

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Aberrant splicing but not mutations of TSG101 in human breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Absence of rearrangements in the tumour susceptibility gene TSG101 in human breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

TSG101 may be the prototype of a class of dominant negative ubiquitin regulators

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

RETRACTED: The TSG101 tumor susceptibility gene is located in chromosome 11 band p15 and is mutated in human breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Tsg101: a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Radiation-induced cell cycle arrest compromised by p21 deficiency

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

An adjunct mammary epithelial cell population in parous females: its role in functional adaptation and tissue renewal.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Tumor susceptibility of p21(Waf1/Cip1)-deficient mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Clinical implications of aberrant TSG101 transcripts in acute myeloblastic leukemia

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Truncated TSG101 transcripts are present in peripheral blood from both familial breast cancer patients and controls.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Tumor surveillance via the ARF-p53 pathway.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

The breast cancer gene product TSG101: a regulator of ubiquitination?

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140677

Aberrant splicing of the TSG101 tumor suppressor gene in human breast and ovarian cancers

27 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/12482969

12 December 2020

Assignment of the murine tumor susceptibility gene 101 (tsg101) and a processed tsg101 pseudogene (tsg101-ps1) to mouse chromosome 7 band B5 and chromosome 15 band D1 by in situ hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/12482969

12 December 2020

Stress-induced aberrant splicing of TSG101: association to high tumor grade and p53 status in breast cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/12482969

12 December 2020

Frequent abnormalities of TSG101 transcripts in human prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12482969

12 December 2020

Oxytocin and milk removal are required for post-partum mammary-gland development

1 reference

https://pubmed.ncbi.nlm.nih.gov/12482969

12 December 2020

10.1128/MCB.23.1.150-162.2003

Identifiers

DOI

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2 August 2017

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2 August 2017

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