Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor (Q34452854)

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24 February 2020

title

Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor (English)

1 reference

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24 February 2020

1 reference

3

1 reference

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24 February 2020

Esra A Akbay

9

1 reference

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24 February 2020

Marzia Capelletti

13

1 reference

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24 February 2020

Signe Regner Michaelsen

18

1 reference

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24 February 2020

Richard A. Young

25

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24 February 2020

Kwok Kin Wong

26

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24 February 2020

2

Nicholas Kwiatkowski

1 reference

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24 February 2020

24

Nathanael S Gray

1 reference

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21

David A Barbie

1 reference

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24 February 2020

5

Fatima Al-Shahrour

1 reference

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24 February 2020

author name string

Camilla L Christensen

1

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24 February 2020

Julian Carretero

4

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24 February 2020

Tinghu Zhang

6

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24 February 2020

Edmond Chipumuro

7

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24 February 2020

Grit S Herter-Sprie

8

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24 February 2020

Abigail Altabef

10

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24 February 2020

Jianming Zhang

11

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24 February 2020

Takeshi Shimamura

12

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24 February 2020

Jakob B Reibel

14

1 reference

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24 February 2020

Jillian D Cavanaugh

15

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24 February 2020

Peng Gao

16

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24 February 2020

Yan Liu

17

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24 February 2020

Hans S Poulsen

19

1 reference

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24 February 2020

Amir R Aref

20

1 reference

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24 February 2020

James E Bradner

22

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24 February 2020

Rani E George

23

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24 February 2020

publication date

1 December 2014

1 reference

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24 February 2020

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24 February 2020

volume

26

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24 February 2020

issue

6

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24 February 2020

page(s)

909-922

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Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

24 February 2020

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1 reference

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6 July 2018

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Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing

6 July 2018

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Acetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase Inhibitors

6 July 2018

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Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells

6 July 2018

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Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer

6 July 2018

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6 July 2018

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Master transcription factors and mediator establish super-enhancers at key cell identity genes

6 July 2018

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NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM.

6 July 2018

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Revisiting global gene expression analysis

6 July 2018

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6 July 2018

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Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

6 July 2018

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Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

6 July 2018

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Subgroup-specific structural variation across 1,000 medulloblastoma genomes

6 July 2018

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Hsp90 globally targets paused RNA polymerase to regulate gene expression in response to environmental stimuli

6 July 2018

1 reference

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Characterization of the cell of origin for small cell lung cancer

6 July 2018

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Nuclear factor I/B is an oncogene in small cell lung cancer

6 July 2018

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Novel strategies for the treatment of small-cell lung carcinoma

6 July 2018

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Selective inhibition of BET bromodomains

6 July 2018

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Array comparative genomic hybridization-based characterization of genetic alterations in pulmonary neuroendocrine tumors.

6 July 2018

1 reference

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Targeted cytosine deaminase-uracil phosphoribosyl transferase suicide gene therapy induces small cell lung cancer-specific cytotoxicity and tumor growth delay

6 July 2018

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A small-cell lung cancer genome with complex signatures of tobacco exposure

6 July 2018

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Lung tumours with neuroendocrine differentiation

6 July 2018

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Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

6 July 2018

1 reference

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Structure, expression, and biological function of INSM1 transcription factor in neuroendocrine differentiation.

6 July 2018

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Achaete-scute complex homologue 1 regulates tumor-initiating capacity in human small cell lung cancer.

6 July 2018

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A translational view of the molecular pathogenesis of lung cancer

6 July 2018

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ASH1 gene is a specific therapeutic target for lung cancers with neuroendocrine features.

6 July 2018

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Achaete-scute homolog-1 and Notch in lung neuroendocrine development and cancer

6 July 2018

1 reference

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Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium

6 July 2018

1 reference

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Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration

6 July 2018

1 reference

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An achaete-scute homologue essential for neuroendocrine differentiation in the lung

6 July 2018

1 reference

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Selective growth in serum-free hormone-supplemented medium of tumor cells obtained by biopsy from patients with small cell carcinoma of the lung

6 July 2018

1 reference

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myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course

6 July 2018

1 reference

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myc family DNA amplification in 107 tumors and tumor cell lines from patients with small cell lung cancer treated with different combination chemotherapy regimens

6 July 2018

1 reference

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Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung.

6 July 2018

1 reference

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Transcriptional gene expression profiling of small cell lung cancer cells

27 October 2018

1 reference

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Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

27 October 2018

1 reference

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Combined microarray analysis of small cell lung cancer reveals altered apoptotic balance and distinct expression signatures of MYC family gene amplification

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25490451

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25490451

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CCELL.2014.10.019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490451%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490451%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

25490451

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490451%20AND%20SRC:MED&resulttype=core&format=json