Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression. (Q34382218)

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7 January 2020

title

Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression (English)

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7 January 2020

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5

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Dwight E. Bergles

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author name string

Jeffrey D Rothstein

1

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7 January 2020

Sarjubhai Patel

2

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Melissa R Regan

3

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Christine Haenggeli

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Lin Jin

7

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Margaret Dykes Hoberg

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Svetlana Vidensky

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Dorothy S Chung

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Shuy Vang Toan

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Lucie I Bruijn

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Zao-Zhong Su

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Pankaj Gupta

14

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Paul B Fisher

15

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language of work or name

English

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publication date

1 January 2005

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7 January 2020

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volume

433

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issue

7021

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page(s)

73-77

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Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

7 January 2020

cites work

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Antisense knockdown of the glial glutamate transporter GLT-1, but not the neuronal glutamate transporter EAAC1, exacerbates transient focal cerebral ischemia-induced neuronal damage in rat brain.

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7 January 2021

Compromised glutamate transport in human glioma cells: reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange

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Insights into glutamate transport regulation in human astrocytes: cloning of the promoter for excitatory amino acid transporter 2 (EAAT2).

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Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1

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Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity

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7 January 2021

Diffusion of ceftriaxone into the cerebrospinal fluid of adults

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7 January 2021

Passage of cefotaxime and ceftriaxone into cerebrospinal fluid of patients with uninflamed meninges

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7 January 2021

In vivo activities of ceftriaxone and vancomycin against Borrelia spp. in the mouse brain and other sites.

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7 January 2021

Expression of a variant form of the glutamate transporter GLT1 in neuronal cultures and in neurons and astrocytes in the rat brain

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7 January 2021

Regulation of the glial Na+-dependent glutamate transporters by cyclic AMP analogs and neurons

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7 January 2021

Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice

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7 January 2021

In vitro ischemic tolerance involves upregulation of glutamate transport partly mediated by the TACE/ADAM17-tumor necrosis factor-alpha pathway.

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7 January 2021

Cu/Zn-superoxide dismutase (GLY93-->ALA) mutation alters AMPA receptor subunit expression and function and potentiates kainate-mediated toxicity in motor neurons in culture

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7 January 2021

Neuroprotective strategies in a model of chronic glutamate-mediated motor neuron toxicity

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7 January 2021

Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

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7 January 2021

Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS.

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7 January 2021

Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).

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7 January 2021

Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis

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7 January 2021

Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication

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7 January 2021

Identifiers

DOI

10.1038/NATURE03180

1 reference

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Dimensions Publication ID

7 January 2020

1047357311

0 references

1 reference