Mitochondrial oxidant stress increases PDE5 activity in persistent pulmonary hypertension of the newborn. (Q34348585)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Mitochondrial oxidant stress increases PDE5 activity in persistent pulmonary hypertension of the newborn (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

main subject

pulmonary hypertension

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Satyan Lakshminrusimha

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Robin H Steinhorn

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Stephen Wedgwood

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Keng Jin Lee

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Lyubov Czech

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Sylvia F Gugino

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Paul T Schumacker

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

publication date

6 September 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

Respiratory Physiology & Neurobiology

13 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

174

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

272-281

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

SOD and inhaled nitric oxide normalize phosphodiesterase 5 expression and activity in neonatal lambs with persistent pulmonary hypertension

13 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Intravenous sildenafil in the treatment of neonates with persistent pulmonary hypertension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Oxygen concentration and pulmonary hemodynamics in newborn lambs with pulmonary hypertension.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

The p53-p66shc-Manganese Superoxide Dismutase (MnSOD) network: a mitochondrial intrigue to generate reactive oxygen species.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Superoxide from NADPH oxidase upregulates type 5 phosphodiesterase in human vascular smooth muscle cells: inhibition with iloprost and NONOate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Hydrogen peroxide decreases endothelial nitric oxide synthase promoter activity through the inhibition of AP-1 activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Hyperoxia increases phosphodiesterase 5 expression and activity in ovine fetal pulmonary artery smooth muscle cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Superoxide dismutase improves oxygenation and reduces oxidation in neonatal pulmonary hypertension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Pulmonary arterial contractility in neonatal lambs increases with 100% oxygen resuscitation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Increased hydrogen peroxide downregulates soluble guanylate cyclase in the lungs of lambs with persistent pulmonary hypertension of the newborn

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Pulmonary vascular biology during neonatal transition.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Sildenafil ameliorates effects of inhaled nitric oxide withdrawal

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Developmental changes in lung cGMP phosphodiesterase-5 activity, protein, and message

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Ventilation and oxygenation induce endothelial nitric oxide synthase gene expression in the lungs of fetal lambs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Inhaled nitric oxide and persistent pulmonary hypertension of the newborn. The Inhaled Nitric Oxide Study Group.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Tolerance of rats to hyperoxia. Lung antioxidant enzyme gene expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Pulmonary vascular remodeling in neonatal pulmonary hypertension. State of the art.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Ligating the ductus arteriosus before birth causes persistent pulmonary hypertension in the newborn lamb.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Superoxide dismutase restores eNOS expression and function in resistance pulmonary arteries from neonatal lambs with persistent pulmonary hypertension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Increased reactive oxygen species production and functional alterations in antioxidant enzymes in human failing myocardium

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Augmented lung injury due to interaction between hyperoxia and mechanical ventilation

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Increased superoxide generation is associated with pulmonary hypertension in fetal lambs: a role for NADPH oxidase

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Resuscitation with room air instead of 100% oxygen prevents oxidative stress in moderately asphyxiated term neonates

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Persistent pulmonary hypertension of the newborn in the era before nitric oxide: practice variation and outcomes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

The cGMP-specific phosphodiesterase inhibitor E4021 dilates the pulmonary circulation.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Phosphodiesterase activity in intrapulmonary arteries and veins of perinatal lambs

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

Oral Sildenafil in Infants With Persistent Pulmonary Hypertension of the Newborn: A Pilot Randomized Blinded Study

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991478

The structural basis of persistent pulmonary hypertension of the newborn infant

27 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804862

12 December 2020

Ligating the ductus arteriosus before birth remodels the pulmonary vasculature of the lamb

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804862

12 December 2020

Rat lung antioxidant enzymes: differences in perinatal gene expression and regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804862

12 December 2020

Inhaled nitric oxide in full-term and nearly full-term infants with hypoxic respiratory failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804862

12 December 2020

Oxidant stress from uncoupled nitric oxide synthase impairs vasodilation in fetal lambs with persistent pulmonary hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804862

12 December 2020

Low-Dose Nitric Oxide Therapy for Persistent Pulmonary Hypertension of the Newborn

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804862

12 December 2020

10.1016/J.RESP.2010.08.018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804862%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

20804862

1 reference