PD-1 blockage reverses immune dysfunction and hepatitis B viral persistence in a mouse animal model (Q34325908)

1 August 2017

title

PD-1 blockage reverses immune dysfunction and hepatitis B viral persistence in a mouse animal model (English)

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1 August 2017

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Horng-Tay Tzeng

1

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1 August 2017

Hwei-Fang Tsai

2

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1 August 2017

Hsiu-Jung Liao

3

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1 August 2017

Yi-Jiun Lin

4

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1 August 2017

Lieping Chen

5

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1 August 2017

Pei-Jer Chen

6

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1 August 2017

Ping-Ning Hsu

7

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1 August 2017

language of work or name

English

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publication date

22 June 2012

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1 August 2017

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1 August 2017

volume

7

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1 August 2017

issue

6

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1 August 2017

page(s)

e39179

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Creative Commons Attribution 4.0 International

1 August 2017

copyright license

start time

22 June 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Hepatitis B virus core antigen determines viral persistence in a C57BL/6 mouse model

1 reference

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Immune effectors required for hepatitis B virus clearance

6 July 2018

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Dynamic decrease in PD-1 expression correlates with HBV-specific memory CD8 T-cell development in acute self-limited hepatitis B patients

6 July 2018

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Enhancing SIV-specific immunity in vivo by PD-1 blockade

6 July 2018

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Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection

6 July 2018

1 reference

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Molecular signature of CD8+ T cell exhaustion during chronic viral infection.

6 July 2018

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Upregulation of PD-1 Expression on Circulating and Intrahepatic Hepatitis C Virus-Specific CD8+ T Cells Associated with Reversible Immune Dysfunction

6 July 2018

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PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver.

6 July 2018

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Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection

6 July 2018

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An immunocompetent mouse model for the tolerance of human chronic hepatitis B virus infection

6 July 2018

1 reference

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

6 July 2018

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T-cell tolerance or function is determined by combinatorial costimulatory signals

6 July 2018

1 reference

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Expression of the interleukin-7 receptor alpha chain (CD127) on virus-specific CD8+ T cells identifies functionally and phenotypically defined memory T cells during acute resolving hepatitis B virus infection

6 July 2018

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Restoring function in exhausted CD8 T cells during chronic viral infection

6 July 2018

1 reference

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Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity

6 July 2018

1 reference

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PD-1 inhibits antiviral immunity at the effector phase in the liver

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382233

Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection

6 July 2018

1 reference

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Immunology of hepatitis B infection

6 July 2018

1 reference

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The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection

6 July 2018

1 reference

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Hepatitis B virus immunopathogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382233

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death

6 July 2018

1 reference

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Intrahepatic PD-1/PD-L1 up-regulation closely correlates with inflammation and virus replication in patients with chronic HBV infection

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039179

Dynamic programmed death 1 expression by virus-specific CD8 T cells correlates with the outcome of acute hepatitis B.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382233

Increased PD-1 and decreased CD28 expression in chronic hepatitis B patients with advanced hepatocellular carcinoma

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22761734

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Antiviral Intrahepatic T-Cell Responses Can Be Restored by Blocking Programmed Death-1 Pathway in Chronic Hepatitis B

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22761734

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0039179

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1 August 2017

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1 August 2017

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