Anxiolytic effects of a novel group II metabotropic glutamate receptor agonist (LY354740) in the fear-potentiated startle paradigm in humans (Q34192256)

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scientific article published on April 23, 2003

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English	Anxiolytic effects of a novel group II metabotropic glutamate receptor agonist (LY354740) in the fear-potentiated startle paradigm in humans	scientific article published on April 23, 2003

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Anxiolytic effects of a novel group II metabotropic glutamate receptor agonist (LY354740) in the fear-potentiated startle paradigm in humans (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

10.1007/S00213-003-1444-8

https://api.crossref.org/works/10.1007/S00213-003-1444-8

26 December 2023

author name string

Christian Grillon

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Jeremy Cordova

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Louise R. Levine

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12709777

26 December 2023

Charles A. Morgan

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12709777

26 December 2023

language of work or name

1 reference

based on heuristic

inferred from title

publication date

23 April 2003

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

full work available at URL

https://zenodo.org/record/1232619/files/article.pdf

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12709777

26 December 2023

http://link.springer.com/content/pdf/10.1007/s00213-003-1444-8.pdf

Portable Document Format

1 reference

10.1007/S00213-003-1444-8

https://api.crossref.org/works/10.1007/S00213-003-1444-8

26 December 2023

http://link.springer.com/article/10.1007/s00213-003-1444-8/fulltext.html

1 reference

10.1007/S00213-003-1444-8

https://api.crossref.org/works/10.1007/S00213-003-1444-8

26 December 2023

http://link.springer.com/content/pdf/10.1007/s00213-003-1444-8

1 reference

10.1007/S00213-003-1444-8

https://api.crossref.org/works/10.1007/S00213-003-1444-8

26 December 2023

Psychopharmacology

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

168

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

446-454

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Effects of threat of shock, shock electrode placement and darkness on startle

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double dissociation between the involvement of the bed nucleus of the stria terminalis and the central nucleus of the amygdala in startle increases produced by conditioned versus unconditioned fear

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The light-enhanced startle paradigm as a putative animal model for anxiety: effects of chlordiazepoxide, flesinoxan and fluvoxamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiogenic effects of high illumination levels assessed with the acoustic startle response in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Group II metabotropic glutamate receptors within the amygdala regulate fear as assessed with potentiated startle in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of alprazolam on the acoustic startle response in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conditioned fear and startle magnitude: effects of different footshock or backshock intensities used in training

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diazepam and flurazepam: Effects on conditioned fear as measured with the potentiated startle paradigm

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the amygdala in fear and anxiety

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Baseline and fear-potentiated startle in panic disorder patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lesions of the amygdala, but not of the cerebellum or red nucleus, block conditioned fear as measured with the potentiated startle paradigm

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of clonidine on the human acoustic startle reflex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of ethanol on the acoustic startle reflex in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comments on the use of the startle reflex in psychopharmacological challenges: impact of baseline startle on measurement of fear-potentiated startle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noradrenergic agonists and antagonists: Effects on conditioned fear as measured by the potentiated startle paradigm

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel functions for subtypes of metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infusion of the non-NMDA receptor antagonist CNQX into the amygdala blocks the expression of fear-potentiated startle

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between LY354740, a group II metabotropic agonist and the GABA(A)-benzodiazepine receptor complex in the rat elevated plus-maze

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fear-potentiated startle conditioning in humans: explicit and contextual cue conditioning following paired versus unpaired training.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are different parts of the extended amygdala involved in fear versus anxiety?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzodiazepines: use, abuse, and consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LY354740, a potent group II metabotropic glutamate receptor agonist prevents lactate-induced panic-like response in panic-prone rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fear-potentiated startle in humans: effects of anticipatory anxiety on the acoustic blink reflex

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of alcohol on baseline startle and prepulse inhibition in young men at risk for alcoholism and/or anxiety disorders.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diazepam blocks fear-potentiated startle in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzodiazepines have no effect on fear-potentiated startle in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Darkness facilitates the acoustic startle reflex in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of alprazolam on the baseline and fear-potentiated startle reflex in humans: a dose-response study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantifying fear potentiated startle using absolute versus proportional increase scoring methods: implications for the neurocircuitry of fear and anxiety

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Light-enhanced startle: further pharmacological and behavioral characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anticipation of a non-aversive reaction time task facilitates the blink startle reflex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of darkness on acoustic startle in Vietnam veterans with PTSD.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic and side-effect profile of LY354740: a potent, highly selective, orally active agonist for group II metabotropic glutamate receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anxiolytic action of mGlu2/3 receptor agonist, LY354740, in the fear-potentiated startle model in rats is mechanistically distinct from diazepam

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of ethanol on acoustic startle response and cerebellar cyclic GMP level: interaction with pilocarpine and atropine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noradrenergic function in panic anxiety. Effects of yohimbine in healthy subjects and patients with agoraphobia and panic disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development and validation of brief measures of positive and negative affect: The PANAS scales

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the effects of diazepam on the fear-potentiated startle reflex and the fear-inhibited light reflex in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00213-003-1444-8

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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