Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in bone (Q34188560)

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English	Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in bone	scientific article

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scholarly article

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10 February 2020

Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in bone (English)

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10 February 2020

mechanosensation

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10 February 2020

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Mohamed A Kamel

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10 February 2020

Nuria Lara-Castillo

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10 February 2020

Mark L Johnson

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10 February 2020

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14 August 2010

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10 February 2020

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10 February 2020

47

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10 February 2020

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10 February 2020

872-881

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10 February 2020

Mechanical induction of PGE2 in osteocytes blocks glucocorticoid-induced apoptosis through both the β-catenin and PKA pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Estrogen receptor and Wnt signaling interact to regulate early gene expression in response to mechanical strain in osteoblastic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Prostaglandin promotion of osteocyte gap junction function through transcriptional regulation of connexin 43 by glycogen synthase kinase 3/beta-catenin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Mechanical loading regulates NFATc1 and beta-catenin signaling through a GSK3beta control node

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Identification of differentially expressed genes between osteoblasts and osteocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Gene expression signatures of a fibroblastoid preosteoblast and cuboidal osteoblast cell model compared to the MLO-Y4 osteocyte cell model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Beta-catenin levels influence rapid mechanical responses in osteoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Mechanical strain inhibits adipogenesis in mesenchymal stem cells by stimulating a durable beta-catenin signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Osteocytes, mechanosensing and Wnt signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Wnt/beta-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Osteoblasts and osteocytes respond differently to oscillatory and unidirectional fluid flow profiles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Mechanically stimulated osteocytes regulate osteoblastic activity via gap junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Fluid shear stress induces less calcium response in a single primary osteocyte than in a single osteoblast: implication of different focal adhesion formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Fluid shear-induced ATP secretion mediates prostaglandin release in MC3T3-E1 osteoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Fluid shear stress induces beta-catenin signaling in osteoblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Mechanotransduction of bone cells in vitro: mechanobiology of bone tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Fluid flow-induced prostaglandin E2 response of osteoblastic ROS 17/2.8 cells is gap junction-mediated and independent of cytosolic calcium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Establishment of an osteocyte-like cell line, MLO-Y4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Mechanotransduction in bone: osteoblasts are more responsive to fluid forces than mechanical strain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Distinct responses of different populations of bone cells to mechanical stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Immortalized murine osteoblasts derived from BMP 2-T-antigen expressing transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Osteocytes, strain detection, bone modeling and remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Function of Osteocytes in Bone—Their Role in Mechanotransduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Pulsating fluid flow increases nitric oxide (NO) synthesis by osteocytes but not periosteal fibroblasts--correlation with prostaglandin upregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Indomethacin modulation of load-related stimulation of new bone formation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

5 July 2018

Osteocytes subjected to fluid flow inhibit osteoclast formation and bone resorption.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

28 October 2018

Evidence that the canonical Wnt signalling pathway regulates deer antler regeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

28 October 2018

Up-regulation of the Wnt, estrogen receptor, insulin-like growth factor-I, and bone morphogenetic protein pathways in C57BL/6J osteoblasts as opposed to C3H/HeJ osteoblasts in part contributes to the differential anabolic response to fluid shear

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

28 October 2018

Influence of increased mechanical loading by hypergravity on the microtubule cytoskeleton and prostaglandin E2 release in primary osteoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

28 October 2018

Bone anabolic responses to mechanical load in vitro involve COX-2 and constitutive NOS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

28 October 2018

Bone biomechanical properties in prostaglandin EP1 and EP2 knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

28 October 2018

Pulsating fluid flow increases prostaglandin production by cultured chicken osteocytes--a cytoskeleton-dependent process.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952691

28 October 2018

Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential stimulation of prostaglandin G/H synthase-2 in osteocytes and other osteogenic cells by pulsating fluid flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluid flow induction of cyclo-oxygenase 2 gene expression in osteoblasts is dependent on an extracellular signal-regulated kinase signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluid flow induces COX-2 expression in MC3T3-E1 osteoblasts via a PKA signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of strain on bone cell prostaglandin E2 release: a new experimental method

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indomethacin has distinct early and late actions on bone formation induced by mechanical stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitivity of osteocytes to biomechanical stress in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanical strain stimulates nitric oxide production by rapid activation of endothelial nitric oxide synthase in osteocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanotransduction in bone does not require a functional cyclooxygenase-2 (COX-2) gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BONE.2010.08.007

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20713195%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PMC publication ID

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Europe PubMed Central

PMC publication ID

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10 February 2020

PubMed publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20713195%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

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