Latrunculin B Reduces Intraocular Pressure in Human Ocular Hypertension and Primary Open-Angle Glaucoma (Q34181305)

31 July 2017

title

Latrunculin B Reduces Intraocular Pressure in Human Ocular Hypertension and Primary Open-Angle Glaucoma (English)

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31 July 2017

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Carol A Rasmussen

1

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31 July 2017

Paul L Kaufman

2

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31 July 2017

Robert Ritch

3

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31 July 2017

Reza Haque

4

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31 July 2017

R Kim Brazzell

5

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31 July 2017

Jason L Vittitow

6

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31 July 2017

publication date

3 September 2014

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Translational vision science & technology

31 July 2017

published in

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31 July 2017

volume

3

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31 July 2017

issue

5

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31 July 2017

page(s)

1

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Emerging trabecular outflow drugs

31 July 2017

cites work

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Comparisons of actin filament disruptors and Rho kinase inhibitors as potential antiglaucoma medications

5 July 2018

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5 July 2018

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eNOS, a pressure-dependent regulator of intraocular pressure.

5 July 2018

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Ocular hypotensive effect of the Rho kinase inhibitor AR-12286 in patients with glaucoma and ocular hypertension

5 July 2018

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The role of the actomyosin system in regulating trabecular fluid outflow

5 July 2018

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Barriers to glaucoma drug delivery

5 July 2018

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The mechanism of increasing outflow facility by rho-kinase inhibition with Y-27632 in bovine eyes.

5 July 2018

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Enhancing trabecular outflow by disrupting the actin cytoskeleton, increasing uveoscleral outflow with prostaglandins, and understanding the pathophysiology of presbyopia interrogating Mother Nature: asking why, asking how, recognizing the signs, fo

5 July 2018

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The number of people with glaucoma worldwide in 2010 and 2020

5 July 2018

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A multicenter, retrospective pilot study of resource use and costs associated with severity of disease in glaucoma.

5 July 2018

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Effects of latrunculin B on outflow facility, intraocular pressure, corneal thickness, and miotic and accommodative responses to pilocarpine in monkeys

5 July 2018

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5 July 2018

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5 July 2018

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Cytoskeletal involvement in the modulation of cell-cell junctions by the protein kinase inhibitor H-7.

5 July 2018

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Phase 2 randomized clinical study of a Rho kinase inhibitor, K-115, in primary open-angle glaucoma and ocular hypertension

5 July 2018

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Effects of latrunculin-B on outflow facility and trabecular meshwork structure in human eyes.

28 October 2018

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28 October 2018

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Caldesmon transgene expression disrupts focal adhesions in HTM cells and increases outflow facility in organ-cultured human and monkey anterior segments.

28 October 2018

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Latrunculin B effects on trabecular meshwork and corneal endothelial morphology in monkeys.

28 October 2018

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Expression of dominant negative Rho-binding domain of Rho-kinase in organ cultured human eye anterior segments increases aqueous humor outflow

28 October 2018

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Functional and structural reversibility of H-7 effects on the conventional aqueous outflow pathway in monkeys

28 October 2018

1 reference

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The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma.

28 October 2018

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Combined effects of H-7 and cytochalasin B on outflow facility in monkeys.

28 October 2018

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H-7 disrupts the actin cytoskeleton and increases outflow facility.

28 October 2018

1 reference

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Latrunculins--novel marine macrolides that disrupt microfilament organization and affect cell growth: I. Comparison with cytochalasin D.

28 October 2018

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Comparison of glaucomatous progression between untreated patients with normal-tension glaucoma and patients with therapeutically reduced intraocular pressures. Collaborative Normal-Tension Glaucoma Study Group

28 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25237590

12 December 2020

Fluctuation of intraocular pressure and glaucoma progression in the early manifest glaucoma trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/25237590

12 December 2020

Latrunculins: novel marine toxins that disrupt microfilament organization in cultured cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25237590

12 December 2020

Effect of H-7 and Lat-B on retinal physiology

1 reference

https://pubmed.ncbi.nlm.nih.gov/25237590

12 December 2020

A 40-year forecast of the demographic shift in primary open-angle glaucoma in the United States

1 reference

https://pubmed.ncbi.nlm.nih.gov/25237590

12 December 2020

Latrunculins' effects on intraocular pressure, aqueous humor flow, and corneal endothelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/25237590

12 December 2020

Effect of latrunculin-B on outflow facility in monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/25237590

12 December 2020

Latrunculin-A increases outflow facility in the monkey

1 reference

https://pubmed.ncbi.nlm.nih.gov/25237590

12 December 2020

Intraocular pressure-lowering effects and safety of topical administration of a selective ROCK inhibitor, SNJ-1656, in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/25237590

12 December 2020

Identifiers

DOI

10.1167/TVST.3.5.1

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31 July 2017

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31 July 2017

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