Characterization of the novel positive allosteric modulator of the metabotropic glutamate receptor 4 ADX88178 in rodent models of neuropsychiatric disorders (Q34125116)

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English	Characterization of the novel positive allosteric modulator of the metabotropic glutamate receptor 4 ADX88178 in rodent models of neuropsychiatric disorders	scientific article

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scholarly article

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31 July 2017

Characterization of the novel positive allosteric modulator of the metabotropic glutamate receptor 4 ADX88178 in rodent models of neuropsychiatric disorders (English)

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31 July 2017

Emmanuel Le Poul

2

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Emmanuel Le Poul

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31 July 2017

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Mikhail Kalinichev

1

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31 July 2017

Christelle Boléa

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31 July 2017

Françoise Girard

4

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31 July 2017

Brice Campo

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31 July 2017

Massimiliano Fonsi

6

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31 July 2017

Isabelle Royer-Urios

7

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31 July 2017

Susan E Browne

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31 July 2017

Jason M Uslaner

9

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31 July 2017

Matthew J Davis

10

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31 July 2017

Jacob Raber

11

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31 July 2017

Robert Duvoisin

12

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31 July 2017

Simon T Bate

13

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31 July 2017

Ian J Reynolds

14

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31 July 2017

Sonia Poli

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31 July 2017

Sylvain Celanire

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31 July 2017

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publication date

19 June 2014

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31 July 2017

Journal of Pharmacology and Experimental Therapeutics

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31 July 2017

350

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31 July 2017

3

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31 July 2017

495-505

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31 July 2017

The antipsychotic-like effects of positive allosteric modulators of metabotropic glutamate mGlu4 receptors in rodents

1 reference

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The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT₁A signalling

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Glutamate-based antidepressants: preclinical psychopharmacology

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The flinders sensitive line rat model of depression--25 years and still producing

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ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization

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Role of mGluR4 in acquisition of fear learning and memory

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A potent and selective metabotropic glutamate receptor 4 positive allosteric modulator improves movement in rodent models of Parkinson's disease

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Long lasting effects of early-life stress on glutamatergic/GABAergic circuitry in the rat hippocampus

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Measures of anxiety, sensorimotor function, and memory in male and female mGluR4⁻/⁻ mice

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Characterization of an mGluR2/3 negative allosteric modulator in rodent models of depression

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GABAB receptor-positive modulators: brain region-dependent effects

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Therapeutic potential of targeting group III metabotropic glutamate receptors in the treatment of Parkinson's disease.

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Glutamatergic theories of schizophrenia.

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Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

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Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

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ADX47273 [S-(4-fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]: a novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activiti

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GABA and glutamate systems as therapeutic targets in depression and mood disorders

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Anxiolytic-like effects of PHCCC, an allosteric modulator of mGlu4 receptors, in rats

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Behavioral, neurochemical, and electrophysiological characterization of a genetic mouse model of depression

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Distribution and synaptic localisation of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS

1 reference

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Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor

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Recent advances in the phencyclidine model of schizophrenia

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Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia

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Peripheral administration of group III mGlu receptor agonist ACPT-I exerts potential antipsychotic effects in rodents

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Identifiers

10.1124/JPET.114.214437

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Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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