A Trabecular Bone Explant Model of Osteocyte-Osteoblast Co-Culture for Bone Mechanobiology (Q34108986)

31 July 2017

title

A Trabecular Bone Explant Model of Osteocyte-Osteoblast Co-Culture for Bone Mechanobiology (English)

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31 July 2017

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Meilin Ete Chan

1

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31 July 2017

Xin L Lu

2

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31 July 2017

Bo Huo

3

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31 July 2017

Andrew D Baik

4

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31 July 2017

Victor Chiang

5

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31 July 2017

Robert E Guldberg

6

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31 July 2017

Helen H Lu

7

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31 July 2017

X Edward Guo

8

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31 July 2017

publication date

1 September 2009

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Cellular and Molecular Bioengineering

31 July 2017

published in

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31 July 2017

volume

2

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31 July 2017

issue

3

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31 July 2017

page(s)

405-415

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Adaptation of connexin 43-hemichannel prostaglandin release to mechanical loading

31 July 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Molecular bases of the sympathetic regulation of bone mass

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Oscillating fluid flow activation of gap junction hemichannels induces ATP release from MLO-Y4 osteocytes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

The influence of mechanical stimulation on osteocyte apoptosis and bone viability in human trabecular bone.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Roles of gap junctions and hemichannels in bone cell functions and in signal transmission of mechanical stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Mechanically stimulated osteocytes regulate osteoblastic activity via gap junctions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Mechanically loaded ex vivo bone culture system 'Zetos': systems and culture preparation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Vascular biology and the skeleton

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Mechanical stimulation of MC3T3 osteoblastic cells in a bone tissue-engineering bioreactor enhances prostaglandin E2 release

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Effects of medium perfusion rate on cell-seeded three-dimensional bone constructs in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Interactive effects of PTH and mechanical stress on nitric oxide and PGE2production by primary mouse osteoblastic cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Functional gap junctions between osteocytic and osteoblastic cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Mechanotransduction in bone--role of the lacuno-canalicular network

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Differential effect of steady versus oscillating flow on bone cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

The role of prostaglandins and nitric oxide in the response of bone to mechanical stimulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Modulation of osteogenesis in fetal bone rudiments by mechanical stress in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Ex Vivo bone formation in bovine trabecular bone cultured in a dynamic 3D bioreactor is enhanced by compressive mechanical strain.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Osteocyte viability and regulation of osteoblast function in a 3D trabecular bone explant under dynamic hydrostatic pressure.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Fluid shear stress induction of COX-2 protein and prostaglandin release in cultured MC3T3-E1 osteoblasts does not require intact microfilaments or microtubules

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Oscillating fluid flow regulates gap junction communication in osteocytic MLO-Y4 cells by an ERK1/2 MAP kinase-dependent mechanism

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Mechanotransduction in bone cells proceeds via activation of COX-2, but not COX-1.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Role of inducible nitric oxide synthase in skeletal adaptation to acute increases in mechanical loading

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

The production of nitric oxide and prostaglandin E(2) by primary bone cells is shear stress dependent

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Osteoblasts respond to pulsatile fluid flow with short-term increases in PGE(2) but no change in mineralization

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Pulsating fluid flow increases prostaglandin production by cultured chicken osteocytes--a cytoskeleton-dependent process.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Mechanical strain-induced NO production by bone cells: a possible role in adaptive bone (re)modeling?

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935082

Fluid shear stress inhibits TNFalpha-induced osteocyte apoptosis

28 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827376

12 December 2020

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827376

12 December 2020

Cultured embryonic bone shafts show osteogenic responses to mechanical loading

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827376

12 December 2020

Novel explant model to study mechanotransduction and cell-cell communication

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827376

12 December 2020

Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827376

12 December 2020

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827376

12 December 2020

Arachidonic acid for loading induced prostacyclin and prostaglandin E(2) release from osteoblasts and osteocytes is derived from the activities of different forms of phospholipase A(2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827376

12 December 2020

Intracellular Ca2+ stores and extracellular Ca2+ are required in the real-time Ca2+ response of bone cells experiencing fluid flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827376

12 December 2020

Role of nitric oxide and prostaglandins in the bone formation response to mechanical loading

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827376

12 December 2020

The role of prostaglandins and nitric oxide in the response of bone to mechanical forces

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827376

12 December 2020

Cellular responses to mechanical loading in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827376

12 December 2020

10.1007/S12195-009-0075-5

Identifiers

DOI

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Dimensions Publication ID

31 July 2017

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31 July 2017

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