Conjugates of cisplatin and cyclooxygenase inhibitors as potent antitumor agents overcoming cisplatin resistance. (Q34060461)

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17 March 2020

title

Conjugates of cisplatin and cyclooxygenase inhibitors as potent antitumor agents overcoming cisplatin resistance (English)

1 reference

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17 March 2020

1 reference

1

1 reference

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17 March 2020

Evamarie Hey-Hawkins

series ordinal

4

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17 March 2020

2

Brenda C Crews

1 reference

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17 March 2020

3

Lawrence J Marnett

1 reference

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17 March 2020

publication date

6 May 2014

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17 March 2020

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17 March 2020

volume

9

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17 March 2020

issue

6

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17 March 2020

page(s)

1150-1153

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Synthesis and characterization of Pt(IV) fluorescein conjugates to investigate Pt(IV) intracellular transformations

17 March 2020

cites work

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Novel tetracarboxylatoplatinum(IV) complexes as carboplatin prodrugs.

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What do we know about the reduction of Pt(IV) pro-drugs?

5 July 2018

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Cisplatin resistance: a cellular self-defense mechanism resulting from multiple epigenetic and genetic changes

5 July 2018

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Redox activation of metal-based prodrugs as a strategy for drug delivery

5 July 2018

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Molecular mechanisms of cisplatin resistance

5 July 2018

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Synthesis, characterization, and cytotoxicity of platinum(IV) carbamate complexes

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Celecoxib antagonizes the cytotoxicity of cisplatin in human esophageal squamous cell carcinoma cells by reducing intracellular cisplatin accumulation

5 July 2018

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Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes

5 July 2018

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Synthesis and Biological Activities of Transition Metal Complexes Based on Acetylsalicylic Acid as Neo-Anticancer Agents

5 July 2018

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The status of platinum anticancer drugs in the clinic and in clinical trials

5 July 2018

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COX-2 as a target for cancer chemotherapy

5 July 2018

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Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents

5 July 2018

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Differential sensitivity and mechanism of inhibition of COX-2 oxygenation of arachidonic acid and 2-arachidonoylglycerol by ibuprofen and mefenamic acid

5 July 2018

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The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

5 July 2018

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The COXIB experience: a look in the rearview mirror

5 July 2018

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Novel di- and tetracarboxylatoplatinum(IV) complexes. Synthesis, characterization, cytotoxic activity, and DNA platination.

5 July 2018

1 reference

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Copper-aspirin complex inhibits cyclooxygenase-2 more selectively than aspirin

5 July 2018

1 reference

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Interaction between celecoxib and docetaxel or cisplatin in human cell lines of ovarian cancer and colon cancer is independent of COX-2 expression levels

5 July 2018

1 reference

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Back to the future: COX-2 inhibitors for chemoprevention and cancer therapy

5 July 2018

1 reference

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Mechanisms of resistance to cisplatin and carboplatin

5 July 2018

1 reference

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Molecular mechanisms of resistance and toxicity associated with platinating agents

5 July 2018

1 reference

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Signalling networks regulating cyclooxygenase-2.

5 July 2018

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Synthesis and characterization of platinum(IV) anticancer drugs with functionalized aromatic carboxylate ligands: influence of the ligands on drug efficacies and uptake

5 July 2018

1 reference

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Inhibition of cytotoxicity of cisplatin by cyclooxygenase-2 inhibitor nimesulide in head and neck cancer cell lines.

5 July 2018

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Augmentation of cisplatin sensitivity in cisplatin-resistant human bladder cancer cells by modulating glutathione concentrations and glutathione-related enzyme activities

5 July 2018

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Mechanisms of platinum drug resistance

5 July 2018

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Rational design of platinum(IV) compounds to overcome glutathione-S-transferase mediated drug resistance.

5 July 2018

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Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition.

5 July 2018

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The cyclooxygenase 2-selective inhibitor NS398 inhibits proliferation of oral carcinoma cell lines by mechanisms dependent and independent of reduced prostaglandin E2 synthesis

5 July 2018

1 reference

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Mechanisms of resistance to cisplatin

5 July 2018

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Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors

5 July 2018

1 reference

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Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): an orally active platinum drug

5 July 2018

1 reference

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A randomized trial of carboplatin versus iproplatin in untreated advanced ovarian cancer.

5 July 2018

1 reference

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The binding of cis-dichlorodiammineplatinum(II) to extracellular and intracellular compounds in relation to drug uptake and cytotoxicity in vitro

5 July 2018

1 reference

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Comparison of cellular accumulation and cytotoxicity of cisplatin with that of tetraplatin and amminedibutyratodichloro(cyclohexylamine)platinum(IV) (JM221) in human ovarian carcinoma cell lines

5 July 2018

1 reference

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Increased cyclooxygenase-2 expression is associated with chemotherapy resistance and poor survival in cervical cancer patients.

5 July 2018

1 reference

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Increased cyclooxygenase-2 (COX-2) expression is associated with chemotherapy resistance and outcome in ovarian cancer patients.

21 January 2018

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Prognostic role of the ratio between cyclooxygenase-2 in tumor and stroma compartments in cervical cancer.

21 January 2018

1 reference

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Synergistic effect of indomethacin with adriamycin and cisplatin on tumor growth

21 January 2018

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Indomethacin increases the cytotoxicity of cis-platinum and 5-fluorouracil in the human uterine cervical cancer cell lines SKG-2 and HKUS by increasing the intracellular uptake of the agents

21 January 2018

1 reference

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Rapid up-regulation of cyclooxygenase-2 by 5-fluorouracil in human solid tumors.

21 January 2018

1 reference

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Novel bis(carboxylato)dichlorido(ethane-1,2-diamine)platinum(IV) complexes with exceptionally high cytotoxicity

21 January 2018

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Celecoxib activates a novel mitochondrial apoptosis signaling pathway

21 January 2018

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COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib

28 October 2018

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Phase I and pharmacokinetic study of ormaplatin (tetraplatin, NSC 363812) administered on a day 1 and day 8 schedule.

28 October 2018

1 reference

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Cisplatin versus cisplatin combined with piroxicam in a canine model of human invasive urinary bladder cancer

28 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24801194

12 December 2020

Carboxylation of Dihydroxoplatinum(IV) Complexes via a New Synthetic Pathway

1 reference

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12 December 2020

Pharmacokinetics and protein binding of cis-dichlorodiammine platinum (II) administered as a one hour or as a twenty hour infusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/24801194

12 December 2020

Tuning the activity of platinum(IV) anticancer complexes through asymmetric acylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24801194

12 December 2020

Metabolism, protein binding and in vivo activity of the oral platinum drug JM216 and its biotransformation products

1 reference

https://pubmed.ncbi.nlm.nih.gov/24801194

12 December 2020

Cyclooxygenase inhibition and hyperthermia for the potentiation of the cytotoxic response in ovarian cancer cells

1 reference

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12 December 2020

Clinical and pharmacological studies with cis-diamminedichloroplatinum (II)

1 reference

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12 December 2020

Identifiers

DOI

10.1002/CMDC.201402074

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24801194%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

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17 March 2020

PubMed publication ID

24801194

1 reference

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