The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection (Q33962536)

30 July 2017

title

The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection (English)

1 reference

30 July 2017

Tatyana V Pestova

1

1 reference

30 July 2017

Victoria G Kolupaeva

series ordinal

2

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30 July 2017

language of work or name

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1 November 2002

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30 July 2017

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30 July 2017

volume

16

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30 July 2017

issue

22

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30 July 2017

page(s)

2906-2922

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Capped mRNAs with Reduced Secondary Structure Can Function in Extracts from Poliovirus-Infected Cells

30 July 2017

cites work

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Gene-specific regulation by general translation factors

5 July 2018

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Preparation and activity of synthetic unmodified mammalian tRNAi(Met) in initiation of translation in vitro

5 July 2018

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Translation initiation factor IF3: two domains, five functions, one mechanism?

5 July 2018

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Truncated initiation factor eIF4G lacking an eIF4E binding site can support capped mRNA translation

5 July 2018

1 reference

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Modulation of the helicase activity of eIF4A by eIF4B, eIF4H, and eIF4F.

5 July 2018

1 reference

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The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure.

5 July 2018

1 reference

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Physical association of eukaryotic initiation factor 4G (eIF4G) with eIF4A strongly enhances binding of eIF4G to the internal ribosomal entry site of encephalomyocarditis virus and is required for internal initiation of translation

5 July 2018

1 reference

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eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

5 July 2018

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The eIF1A solution structure reveals a large RNA-binding surface important for scanning function

5 July 2018

1 reference

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The joining of ribosomal subunits in eukaryotes requires eIF5B.

5 July 2018

1 reference

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Eukaryotic translation initiation factor 4E (eIF4E) binding site and the middle one-third of eIF4GI constitute the core domain for cap-dependent translation, and the C-terminal one-third functions as a modulatory region

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure

5 July 2018

1 reference

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Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons

5 July 2018

1 reference

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Translational activation of uncapped mRNAs by the central part of human eIF4G is 5' end-dependent

5 July 2018

1 reference

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The Mof2/Sui1 protein is a general monitor of translational accuracy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initiation of hepatitis C and classical swine fever virus RNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Human eukaryotic translation initiation factor 4G (eIF4G) possesses two separate and independent binding sites for eIF4A

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

The structure of the translational initiation factor IF1 from E.coli contains an oligomer-binding motif

5 July 2018

1 reference

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Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

The p46 subunit of eukaryotic initiation factor (eIF)-4F exchanges with eIF-4A

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Mapping of functional domains in eukaryotic protein synthesis initiation factor 4G (eIF4G) with picornaviral proteases. Implications for cap-dependent and cap-independent translational initiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Secondary structure of mouse and rabbit alpha- and beta-globin mRNAs: differential accessibility of alpha and beta initiator AUG codons towards nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

5'-Conformation of capped alfalfa mosaic virus ribonucleic acid may reflect its independence of the cap structure or of cap-binding protein for efficient translation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

5'-terminal cap structure in eucaryotic messenger ribonucleic acids.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Secondary structure model for mouse beta Maj globin mRNA derived from enzymatic digestion data, comparative sequence and computer analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Influences of mRNA secondary structure on initiation by eukaryotic ribosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Insertion mutagenesis to increase secondary structure within the 5' noncoding region of a eukaryotic mRNA reduces translational efficiency.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Selection of the initiator tRNA by Escherichia coli initiation factors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

The scanning model for translation: an update

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Translation initiation at non-AUG triplets in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Downstream secondary structure facilitates recognition of initiator codons by eukaryotic ribosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Translation initiation at a downstream AUG occurs with increased efficiency when the upstream AUG is located very close to the 5' cap.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Interaction of wheat germ protein synthesis initiation factors eIF-3, eIF-(iso)4F, and eIF-4F with mRNA analogues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Structural features in eukaryotic mRNAs that modulate the initiation of translation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Analysis of 40 S and 80 S complexes with mRNA as measured by sucrose density gradients and primer extension inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

The suil suppressor locus in Saccharomyces cerevisiae encodes a translation factor that functions during tRNA(iMet) recognition of the start codon

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Domains of initiator tRNA and initiation codon crucial for initiator tRNA selection by Escherichia coli IF3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

How do eucaryotic ribosomes select initiation regions in messenger RNA?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

A short leader sequence impairs the fidelity of initiation by eukaryotic ribosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Interaction of translation initiation factor 3 with the 30S ribosomal subunit

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Initiation factor 3-induced structural changes in the 30 S ribosomal subunit and in complexes containing tRNA(f)(Met) and mRNA.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Translation initiation factor 3 antagonizes authentic start codon selection on leaderless mRNAs

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Ribosome-messenger recognition in the absence of the Shine-Dalgarno interactions.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

From stand-by to decoding site. Adjustment of the mRNA on the 30S ribosomal subunit under the influence of the initiation factors.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Role of ATP in binding and migration of 40S ribosomal subunits

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187480

Influence of mRNA secondary structure on binding and migration of 40S ribosomal subunits

29 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/12435632

12 December 2020

ATP-dependent unwinding of messenger RNA structure by eukaryotic initiation factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12435632

12 December 2020

tRNAi(met) functions in directing the scanning ribosome to the start site of translation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12435632

12 December 2020

Translation of an uncapped mRNA involves scanning

1 reference

https://pubmed.ncbi.nlm.nih.gov/12435632

12 December 2020

Identifiers

DOI

10.1101/GAD.1020902

1 reference

30 July 2017

1 reference

30 July 2017

1 reference