Hypoxia, clonal selection, and the role of HIF-1 in tumor progression (Q33924693)

30 July 2017

1 reference

title

Hypoxia, clonal selection, and the role of HIF-1 in tumor progression (English)

1 reference

30 July 2017

0 references

1 reference

1

Semenza GL

1 reference

30 July 2017

publication date

1 January 2000

1 reference

Critical Reviews in Biochemistry and Molecular Biology

30 July 2017

published in

1 reference

30 July 2017

volume

35

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30 July 2017

issue

2

1 reference

30 July 2017

page(s)

71-103

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

30 July 2017

cites work

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/20459

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Differential activation of the rat phenylethanolamine N-methyltransferase gene by Sp1 and Egr-1.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Remembrance of things PAS: regulation of development by bHLH-PAS proteins

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Expression and distribution of vascular endothelial growth factor protein in human brain tumors

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Novel anticancer drug discovery

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

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1 reference

12 October 2022

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Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

1 reference

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1 reference

12 October 2022

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Nucleotide sequence of an avian sarcoma virus oncogene (src) and proposed amino acid sequence for gene product

1 reference

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1 reference

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1 reference

12 October 2022

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1 reference

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1 reference

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1 reference

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1 reference

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Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene

1 reference

12 October 2022

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1 reference

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1 reference

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Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

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Tumour angiogenesis and prognosis.

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p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts

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Hypoxia stimulates insulin-like growth factor binding protein 1 (IGFBP-1) gene expression in HepG2 cells: a possible model for IGFBP-1 expression in fetal hypoxia

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Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase

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1 reference

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1 reference

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1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

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1 reference

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Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Transferrin receptor induction by hypoxia. HIF-1-mediated transcriptional activation and cell-specific post-transcriptional regulation

1 reference

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Identification of a hypoxia response element in the transferrin receptor gene

1 reference

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1 reference

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Vascular endothelial growth factor and neovascularization in astrocytic tumors.

1 reference

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Early induction of angiogenetic signals in gliomas of GFAP-v-src transgenic mice

1 reference

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ARNT-deficient mice and placental differentiation

1 reference

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p53 mutations in human cancers

1 reference

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Mutagenesis induced by the tumor microenvironment

1 reference

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The mouse gene for vascular endothelial growth factor. Genomic structure, definition of the transcriptional unit, and characterization of transcriptional and post-transcriptional regulatory sequences

1 reference

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The p53 tumour suppressor gene

1 reference

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Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

1 reference

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Stat3 activation is required for cellular transformation by v-src

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Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha

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1 reference

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A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter

1 reference

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Putative control of angiogenesis in hemangioblastomas by the von Hippel-Lindau tumor suppressor gene.

1 reference

12 October 2022

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p53 inhibits hypoxia-inducible factor-stimulated transcription

1 reference

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Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

1 reference

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Characterization of the alpha1B-adrenergic receptor gene promoter region and hypoxia regulatory elements in vascular smooth muscle

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Induction of vascular endothelial growth factor by tumor necrosis factor alpha in human glioma cells. Possible roles of SP-1.

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Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

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Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways

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The implications of angiogenesis for the biology and therapy of cancer metastasis

1 reference

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Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer

1 reference

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Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathways

1 reference

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

1 reference

12 October 2022

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Stat3 activation by Src induces specific gene regulation and is required for cell transformation

1 reference

12 October 2022

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

12 October 2022

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Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1

1 reference

12 October 2022

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Hypoxia and platelet-derived growth factor-BB synergistically upregulate the expression of vascular endothelial growth factor in vascular smooth muscle cells

1 reference

12 October 2022

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Angiogenesis and tumor metastasis

1 reference

12 October 2022

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Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance.

1 reference

12 October 2022

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Hypoxia-inducible Factor-1 Mediates Transcriptional Activation of the Heme Oxygenase-1 Gene in Response to Hypoxia

1 reference

12 October 2022

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Hypoxic Regulation of Lactate Dehydrogenase A

1 reference

12 October 2022

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Oncogenic alterations of metabolism

1 reference

12 October 2022

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Glycolysis and methylaminoisobutyrate uptake in rat-1 cells transfected with ras or myc oncogenes

1 reference

12 October 2022

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What Is the Evidence That Tumors Are Angiogenesis Dependent?

1 reference

12 October 2022

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Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

1 reference

12 October 2022

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Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia.

1 reference

12 October 2022

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Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

1 reference

12 October 2022

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An essential role for p300/CBP in the cellular response to hypoxia

1 reference

12 October 2022

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Impact of oncogenes in tumor angiogenesis: mutant K-ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells

1 reference

12 October 2022

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Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

1 reference

12 October 2022

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The clonal evolution of tumor cell populations

1 reference

12 October 2022

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Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression

1 reference

12 October 2022

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Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

1 reference

12 October 2022

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1 reference

12 October 2022

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1 reference

12 October 2022

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Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

1 reference

12 October 2022

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Induction of the Plasminogen Activator Inhibitor-1 Gene Expression by Mild Hypoxia Via a Hypoxia Response Element Binding the Hypoxia-Inducible Factor-1 in Rat Hepatocytes

1 reference

12 October 2022

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Aerobic glycolysis by proliferating cells: a protective strategy against reactive oxygen species.

1 reference

12 October 2022

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Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor

1 reference

12 October 2022

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Regulation of p53 stability by Mdm2

1 reference

12 October 2022

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Gene expression profiles in normal and cancer cells

1 reference

12 October 2022

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Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

1 reference

12 October 2022

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Disruption of p53 in human cancer cells alters the responses to therapeutic agents

1 reference

12 October 2022

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Normoxic and hypoxic regulation of vascular endothelial growth factor (VEGF) by astrocytoma cells is mediated by Ras.

1 reference

12 October 2022

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Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

1 reference

12 October 2022

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aHIF: a natural antisense transcript overexpressed in human renal cancer and during hypoxia

1 reference

12 October 2022

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Expression of vascular endothelial growth factor and its receptors in pilocytic astrocytoma.

1 reference

12 October 2022

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Regulation of proliferation-survival decisions during tumor cell hypoxia

1 reference

12 October 2022

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p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Induction of vascular endothelial growth factor by insulin-like growth factor 1 in colorectal carcinoma

1 reference

12 October 2022

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Targeting gene expression to hypoxic tumor cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Reversion of transformed glycolysis to normal by inhibition of protein synthesis in rat kidney cells infected with temperature-sensitive mutant of Rous sarcoma virus

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Tumour hypoxia: the picture has changed in the 1990s

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/10409230091169186

Identifiers

DOI

10.1080/10409230091169186

1 reference

30 July 2017

1 reference