Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases. (Q33889765)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9799222%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

title

Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases (English)

1 reference

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6 December 2019

0 references

1

1 reference

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6 December 2019

Mikala Egeblad

5

1 reference

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6 December 2019

author name string

D Wissing

2

1 reference

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6 December 2019

K Kokholm

3

1 reference

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6 December 2019

T Kallunki

4

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6 December 2019

language of work or name

English

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publication date

1 November 1998

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6 December 2019

1 reference

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6 December 2019

volume

17

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issue

21

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6 December 2019

page(s)

6124-6134

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TNF-induced mitochondrial changes and activation of apoptotic proteases are inhibited by A20.

6 December 2019

cites work

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Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1

5 July 2018

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Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

5 July 2018

1 reference

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Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

5 July 2018

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Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis

5 July 2018

1 reference

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

5 July 2018

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Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis

5 July 2018

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The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

5 July 2018

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X-linked IAP is a direct inhibitor of cell-death proteases

5 July 2018

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The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis

5 July 2018

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Involvement of caspase-dependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis

5 July 2018

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Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor

5 July 2018

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DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

5 July 2018

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Apoptosis by death factor

5 July 2018

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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

5 July 2018

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

5 July 2018

1 reference

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Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway

5 July 2018

1 reference

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Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis

5 July 2018

1 reference

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Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

5 July 2018

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Differential expression of 70-kDa heat shock-protein in human oral tumorigenesis

5 July 2018

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Mitochondria are selective targets for the protective effects of heat shock against oxidative injury

5 July 2018

1 reference

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

5 July 2018

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HSP70 overexpression mediates the escape of a doxorubicin-induced G2 cell cycle arrest.

5 July 2018

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Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

5 July 2018

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Life, death, and the pursuit of apoptosis.

5 July 2018

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The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

5 July 2018

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Negative regulation of immunoglobulin kappa light-chain gene transcription by a short sequence homologous to the murine B1 repetitive element

5 July 2018

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Heat shock protein hsp70 in patients with axillary lymph node-negative breast cancer: prognostic implications

5 July 2018

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Heat-shock proteins protect cells from monocyte cytotoxicity: possible mechanism of self-protection

5 July 2018

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Overexpression of major heat shock protein hsp70 inhibits tumor necrosis factor-induced activation of phospholipase A2.

5 July 2018

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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

5 July 2018

1 reference

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Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

5 July 2018

1 reference

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Apoptosis. Its significance in cancer and cancer therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170939

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170939

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170939

Heat shock protein 70 overexpression affects the response to ultraviolet light in murine fibroblasts. Evidence for increased cell viability and suppression of cytokine release

5 July 2018

1 reference

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Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170939

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

5 July 2018

1 reference

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Bcl-x and Bcl-2 inhibit TNF and Fas-induced apoptosis and activation of phospholipase A2 in breast carcinoma cells.

5 July 2018

1 reference

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Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product

5 July 2018

1 reference

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

5 July 2018

1 reference

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Correlation between synthesis of heat shock proteins and development of thermotolerance in Chinese hamster fibroblasts

5 July 2018

1 reference

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

5 July 2018

1 reference

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Expression of human HSP70 during the synthetic phase of the cell cycle

5 July 2018

1 reference

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Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

5 July 2018

1 reference

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Heat shock protects WEHI-164 target cells from the cytolysis by tumor necrosis factors alpha and beta.

5 July 2018

1 reference

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Use of polymerase chain reaction to detect the expression of the Mr 70,000 heat shock genes in control or heat shock leukemic cells as correlated to their heat response

5 July 2018

1 reference

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Unusual expression and localization of heat-shock proteins in human tumor cells

5 July 2018

1 reference

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Major heat shock protein hsp70 protects tumor cells from tumor necrosis factor cytotoxicity

5 July 2018

1 reference

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Heat shock is lethal to fibroblasts microinjected with antibodies against hsp70

5 July 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/9799222

12 December 2020

Competitive inhibition of hsp70 gene expression causes thermosensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9799222

12 December 2020

Over-expression of hsp70 confers tumorigenicity to mouse fibrosarcoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9799222

12 December 2020

T cell lymphoma in transgenic mice expressing the human Hsp70 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9799222

12 December 2020

Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9799222

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/17.21.6124

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9799222%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference

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6 December 2019

PubMed publication ID

9799222

1 reference