The Ras branch of small GTPases: Ras family members don't fall far from the tree (Q33860507)

29 July 2017

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title

The Ras branch of small GTPases: Ras family members don't fall far from the tree (English)

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29 July 2017

Reuther GW

1

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29 July 2017

Der CJ

series ordinal

2

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29 July 2017

publication date

1 April 2000

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Current Opinion in Cell Biology

29 July 2017

published in

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29 July 2017

volume

12

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29 July 2017

issue

2

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29 July 2017

page(s)

157-165

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

29 July 2017

1 reference

7 January 2021

Increasing complexity of Ras signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Rho GTPases and signaling networks

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

The murine N-ras gene is not essential for growth and development

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

The Saccharomyces cerevisiae prenylcysteine carboxyl methyltransferase Ste14p is in the endoplasmic reticulum membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Endoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Functional rafts in cell membranes

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

The caveolae membrane system

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Involvement of caveolin-1 in meiotic cell-cycle progression in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Aberrant function of the Ras-related protein TC21/R-Ras2 triggers malignant transformation.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

TC21 causes transformation by Raf-independent signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

A human oncogene of the RAS superfamily unmasked by expression cDNA cloning

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Integrin activation by R-ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Suppression of integrin activation: a novel function of a Ras/Raf-initiated MAP kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Novel small GTPase M-Ras participates in reorganization of actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Identification and characterization of R-ras3: a novel member of the RAS gene family with a non-ubiquitous pattern of tissue distribution

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Association of the Ras-antagonistic Rap1/Krev-1 proteins with the Golgi complex

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Effect of phosphorylation on activities of Rap1A to interact with Raf-1 and to suppress Ras-dependent Raf-1 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Rapid Ca2+-mediated activation of Rap1 in human platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Activation of the Rap1 GTPase by the B cell antigen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Costimulation through CD28 suppresses T cell receptor-dependent activation of the Ras-like small GTPase Rap1 in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

A family of cAMP-binding proteins that directly activate Rap1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Characterization of GFR, a novel guanine nucleotide exchange factor for Rap1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

nRap GEP: a novel neural GDP/GTP exchange protein for rap1 small G protein that interacts with synaptic scaffolding molecule (S-SCAM)

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Ras caught in another affair: the exchange factors for Ral.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

RalA requirement for v-Src- and v-Ras-induced tumorigenicity and overproduction of urokinase-type plasminogen activator: involvement of metalloproteases

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Ral-specific guanine nucleotide exchange factor activity opposes other Ras effectors in PC12 cells by inhibiting neurite outgrowth

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Ras-independent activation of Ral by a Ca(2+)-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Signaling pathways in Ras-mediated tumorigenicity and metastasis.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Synergistic activation of c-fos promoter activity by Raf and Ral GDP dissociation stimulator

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Characterization of Ral GDP dissociation stimulator-like (RGL) activities to regulate c-fos promoter and the GDP/GTP exchange of Ral.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Stimulation of gene induction and cell growth by the Ras effector Rlf

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Multiple ras effector pathways contribute to G(1) cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Direct control of the Forkhead transcription factor AFX by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Induction of Rheb mRNA following middle cerebral artery occlusion in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

Biochemical characterization of the Ras-related GTPases Rit and Rin

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900071-X

7 January 2021

10.1016/S0955-0674(99)00071-X

Identifiers

DOI

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29 July 2017

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