Bacterial proteinases as targets for the development of second-generation antibiotics (Q33857438)

29 July 2017

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title

Bacterial proteinases as targets for the development of second-generation antibiotics (English)

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29 July 2017

2

J Potempa

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29 July 2017

J Travis

1

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29 July 2017

language of work or name

English

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publication date

1 March 2000

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Biochimica et Biophysica Acta

29 July 2017

published in

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29 July 2017

volume

1477

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29 July 2017

issue

1-2

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29 July 2017

page(s)

35-50

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The HIV protease and therapies for AIDS.

29 July 2017

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Are bacterial proteinases pathogenic factors?

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Role of microbial proteases in pathogenesis

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Inactivation of human plasma alpha 1-proteinase inhibitor by a metalloproteinase from Serratia marcescens

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Purification and characterization of a novel endopeptidase in ragweed (Ambrosia artemisiifolia) pollen

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Interactions of α-1-Antichymotrypsin, α-1-Proteinase Inhibitor, and α-2-Macroglobulin with the Fungal Enzyme, Seaprose

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Enzymatic inactivation of human antithrombin III. Limited proteolysis of the inhibitor by snake venom proteinases in the presence of heparin

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Plakalbumin, alpha 1-antitrypsin, antithrombin and the mechanism of inflammatory thrombosis

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Mobile reactive centre of serpins and the control of thrombosis

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7 January 2021

The structural basis for neutrophil inactivation of C1 inhibitor.

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7 January 2021

Inactivation of human plasma C1-inhibitor by human PMN leucocyte matrix metalloproteinases

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Analysis of the plasma elimination kinetics and conformational stabilities of native, proteinase-complexed, and reactive site cleaved serpins: comparison of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, antithrombin III, alpha 2-antiplasmi

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The primary elastase inhibitor (elastasin) and trypsin inhibitor (contrapsin) in the goat are serpins related to human alpha 1-anti-chymotrypsin

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7 January 2021

Comparative properties of two cysteine proteinases (gingipains R), the products of two related but individual genes of Porphyromonas gingivalis

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7 January 2021

The role of proteolytic enzymes in the development of pulmonary emphysema and periodontal disease

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7 January 2021

Activation of human matrix metalloproteinases by various bacterial proteinases

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7 January 2021

Human matrix metalloprotease activation by insults of bacterial infection involving proteases and free radicals

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7 January 2021

Activation and novel processing of matrix metalloproteinases by a thiol-proteinase from the oral anaerobe Porphyromonas gingivalis

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7 January 2021

Capturing host plasmin(ogen): a common mechanism for invasive pathogens?

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7 January 2021

Production of chemotactic factors for neutrophils following the interaction of Bacteroides gingivalis with purified C5

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7 January 2021

The effect of periodontal proteolytic Bacteroides species on proteins of the human complement system

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The role of complement in periodontal diseases

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Collagenases (first of three parts).

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The IgA1 proteases of pathogenic bacteria

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7 January 2021

Biological significance of IgA1 proteases in bacterial colonization and pathogenesis: critical evaluation of experimental evidence

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7 January 2021

The cleavage of immunoglobulin G in vitro and in vivo by a proteinase secreted by the urinary tract pathogen Proteus mirabilis

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A proteolytic enzyme secreted by Proteus mirabilis degrades immunoglobulins of the immunoglobulin A1 (IgA1), IgA2, and IgG isotypes

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7 January 2021

Degradation of plasma proteins by the trypsin-like enzyme of Porphyromonas gingivalis and inhibition of protease activity by a serine protease inhibitor of human plasma

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7 January 2021

Cleavage of human immunoglobulins by serine proteinase from Staphylococcus aureus

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7 January 2021

Characterization of immunoglobulin G-degrading proteases of Prevotella intermedia and Prevotella nigrescens

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7 January 2021

Pathogenesis of periodontitis: a major arginine-specific cysteine proteinase from Porphyromonas gingivalis induces vascular permeability enhancement through activation of the kallikrein/kinin pathway

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7 January 2021

A serratial protease causes vascular permeability reaction by activation of the Hageman factor-dependent pathway in guinea pigs

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7 January 2021

Activation of bradykinin generating cascade by Vibrio cholerae protease.

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7 January 2021

Streptococcal cysteine proteinase releases kinins: a virulence mechanism

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7 January 2021

Involvement of bradykinin generation in intravascular dissemination of Vibrio vulnificus and prevention of invasion by a bradykinin antagonist.

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7 January 2021

Bradykinin generation triggered by Pseudomonas proteases facilitates invasion of the systemic circulation by Pseudomonas aeruginosa

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7 January 2021

Effect of Pseudomonas aeruginosa elastase and alkaline protease on serum complement and isolated components C1q and C3

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7 January 2021

Elastase of Pseudomonas aeruginosa: inactivation of complement components and complement-derived chemotactic and phagocytic factors

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7 January 2021

Degradation of human immunoglobulins G and M and complement factors C3 and C5 by black-pigmented Bacteroides

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7 January 2021

Activation of blood clotting factors by microbial proteinases

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7 January 2021

Activation of protein C by arginine-specific cysteine proteinases (gingipains-R) from Porphyromonas gingivalis

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Activation of blood coagulation factor X by arginine-specific cysteine proteinases (gingipain-Rs) from Porphyromonas gingivalis

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Oral pathogens: from dental plaque to cardiac disease

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7 January 2021

The pathobiology of periodontal diseases may affect systemic diseases: inversion of a paradigm

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Purification and characterisation of a plasminogen-binding protein from Haemophilus influenzae. Sequence determination reveals identity with aspartase

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Receptors for human plasminogen on gram-negative bacteria

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7 January 2021

Binding of plasminogen to Neisseria meningitidis and Neisseria gonorrhoeae and formation of surface-associated plasmin.

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Binding and activation of plasminogen at the surface of Staphylococcus aureus. Increase in affinity after conversion to the Lys form of the ligand

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Selective distribution of a high-affinity plasminogen-binding site among group A streptococci associated with impetigo

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7 January 2021

Surface bound plasmin promotes migration of Streptococcus pneumoniae through reconstituted basement membranes

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Interaction of a group A Streptococcus within human plasma results in assembly of a surface plasminogen activator that contributes to occupancy of surface plasmin-binding structures

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A surface protease and the invasive character of plague

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Effect of free and vesicle-bound cysteine proteinases of Porphyromonas gingivalis on plasma clot formation: implications for bleeding tendency at periodontitis sites

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Characterization of the binding activities of proteinase-adhesin complexes from Porphyromonas gingivalis

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Pseudomonas aeruginosa alkaline proteinase might share a biological function with plasmin.

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7 January 2021

Protease IV, a unique extracellular protease and virulence factor from Pseudomonas aeruginosa

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7 January 2021

Legionella pneumophila protease inactivates interleukin-2 and cleaves CD4 on human T cells

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7 January 2021

Inactivation of human gamma interferon by Pseudomonas aeruginosa proteases: elastase augments the effects of alkaline protease despite the presence of alpha 2-macroglobulin

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7 January 2021

Inactivation of tumor necrosis factor-alpha by proteinases (gingipains) from the periodontal pathogen, Porphyromonas gingivalis. Implications of immune evasion

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Cytokine degradation by biofilms of Porphyromonas gingivalis

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7 January 2021

Interactions between periodontopathogenic bacteria and cytokines

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7 January 2021

Rapid and efficient inactivation of IL-6 gingipains, lysine- and arginine-specific proteinases from Porphyromonas gingivalis

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Modulation of interleukin-8 activity by gingipains from Porphyromonas gingivalis: implications for pathogenicity of periodontal disease

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Interleukin-8 processing by neutrophil elastase, cathepsin G and proteinase-3.

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IL-8 degradation by Porphyromonas gingivalis proteases

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Novel pathogenic mechanism of microbial metalloproteinases: liberation of membrane-anchored molecules in biologically active form exemplified by studies with the human interleukin-6 receptor

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7 January 2021

Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from Porphyromonas gingivalis

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7 January 2021

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

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7 January 2021

Role of Staphylococcus protease in the development of influenza pneumonia

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7 January 2021

Synergistic role of staphylococcal proteases in the induction of influenza virus pathogenicity

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7 January 2021

Interactions between bacteria and influenza A virus in the development of influenza pneumonia

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7 January 2021

Advances in the pathogenesis of periodontitis: summary of developments, clinical implications and future directions

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7 January 2021

The microbial challenge in periodontitis

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7 January 2021

Role of bacterial proteinases in matrix destruction and modulation of host responses

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7 January 2021

Adhere today, here tomorrow: oral bacterial adherence

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7 January 2021

Porphyromonas gingivalis trypsin-like protease: a possible natural ligand for the neutrophil formyl peptide receptor

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7 January 2021

Dependence of vascular permeability enhancement on cysteine proteinases in vesicles of Porphyromonas gingivalis

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7 January 2021

10.1016/S0167-4838(99)00278-2

Identifiers

DOI

1 reference

29 July 2017

1 reference