An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence (Q33819643)

29 July 2017

title

An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence (English)

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Shizuo Akira

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Bruce Beutler

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object named as

Bruce Beutler

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29 July 2017

Owen M Siggs

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author name string

Michael Berger

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Xiaohong Li

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Daniel Popkin

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Xin Du

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Brian R Lawson

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Argyrios N Theofilopoulos

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Yu Xia

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Kevin Khovananth

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Eva Marie Moresco

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Takashi Satoh

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Osamu Takeuchi

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language of work or name

English

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publication date

28 February 2010

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volume

11

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issue

4

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29 July 2017

page(s)

335-343

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Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands

29 July 2017

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Molecular signature of cell cycle exit induced in human T lymphoblasts by IL-2 withdrawal

4 July 2018

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NK-cell-mediated killing of target cells triggers robust antigen-specific T-cell-mediated and humoral responses

4 July 2018

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4 July 2018

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Critical roles of the PI3K/Akt signaling pathway in T cell development

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

4 July 2018

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Kruppel-like factor 2 regulates thymocyte and T-cell migration

4 July 2018

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Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis

4 July 2018

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A major histocompatibility complex class I-dependent subset of memory phenotype CD8+ cells

4 July 2018

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A new description of cellular quiescence

4 July 2018

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AAA+ proteins: have engine, will work

4 July 2018

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Schlafen-1 causes a cell cycle arrest by inhibiting induction of cyclin D1

4 July 2018

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NFAT proteins: key regulators of T-cell development and function

4 July 2018

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Mitogen-activated protein kinases in apoptosis regulation

4 July 2018

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Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim

4 July 2018

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Regulation of quiescence in lymphocytes

4 July 2018

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JNK and p38 MAP kinases in CD4+ and CD8+ T cells

4 July 2018

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Lymphocide: cytokines and the control of lymphoid homeostasis

4 July 2018

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NF-kappaB regulation in the immune system

4 July 2018

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Genetic control of innate immune responses against cytomegalovirus: MCMV meets its match

4 July 2018

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Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.

4 July 2018

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Defense against influenza A virus infection: essential role of the chemokine system

4 July 2018

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Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells

4 July 2018

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B-lymphocyte quiescence, tolerance and activation as viewed by global gene expression profiling on microarrays

4 July 2018

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Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation

4 July 2018

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Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells

4 July 2018

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Homeostatic expansion and phenotypic conversion of naïve T cells in response to self peptide/MHC ligands

4 July 2018

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Activation changes the spectrum but not the diversity of genes expressed by T cells.

4 July 2018

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Schlafen, a new family of growth regulatory genes that affect thymocyte development

4 July 2018

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Quiescence-inducing and antiapoptotic activities of IL-15 enhance secondary CD4+ T cell responsiveness to antigen.

4 July 2018

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Lps2: a new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening

4 July 2018

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Crossref

https://api.crossref.org/works/10.1038%2FNI.1847

PanR1, a dominant negative missense allele of the gene encoding TNF-alpha (Tnf), does not impair lymphoid development

21 January 2018

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https://api.crossref.org/works/10.1038%2FNI.1847

Removal of lymphoid organs

21 January 2018

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Analysis of the MCMV resistome by ENU mutagenesis

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861894

eXPRESSION: an in silico tool to predict patterns of gene expression.

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861894

Modulation of T cell development and activation by novel members of the Schlafen (slfn) gene family harbouring an RNA helicase-like motif.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861894

Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc-dependent pathway

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2861894

Sequential MyD88-independent and -dependent activation of innate immune responses to intracellular bacterial infection

29 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20190759

12 December 2020

Mechanisms of L-selectin regulation by activated T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20190759

12 December 2020

LKLF: A transcriptional regulator of single-positive T cell quiescence and survival

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https://pubmed.ncbi.nlm.nih.gov/20190759

12 December 2020

Differentiation of naive CTL to effector and memory CTL: correlation of effector function with phenotype and cell division

1 reference

https://pubmed.ncbi.nlm.nih.gov/20190759

12 December 2020

Kruppel-like factor 2 controls T cell trafficking by activating L-selectin (CD62L) and sphingosine-1-phosphate receptor 1 transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/20190759

12 December 2020

IL-7/anti-IL-7 mAb complexes restore T cell development and induce homeostatic T Cell expansion without lymphopenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20190759

12 December 2020

Identifiers

DOI

10.1038/NI.1847

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29 July 2017

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29 July 2017

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