The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. (Q33722837)

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English	The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1.	scientific article

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1 January 2020

The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1 (English)

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1 January 2020

Alzheimer's disease

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Wang-Xia Wang

1

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1 January 2020

Bernard W Rajeev

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1 January 2020

Arnold J Stromberg

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1 January 2020

Na Ren

4

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1 January 2020

Guiliang Tang

5

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1 January 2020

Qingwei Huang

6

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1 January 2020

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1 January 2008

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1 January 2020

Journal of Neuroscience

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1 January 2020

28

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1 January 2020

5

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1 January 2020

1213-1223

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1 January 2020

Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles "do count" when staging disease severity

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21 June 2018

A MicroRNA feedback circuit in midbrain dopamine neurons

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miRNAs: from neurogeneration to neurodegeneration

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A simple array platform for microRNA analysis and its application in mouse tissues.

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Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells

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MicroRNA targeting specificity in mammals: determinants beyond seed pairing

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Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity

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21 June 2018

RNA in brain disease: no longer just "the messenger in the middle".

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An mRNA m7G cap binding-like motif within human Ago2 represses translation

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Energizing miRNA research: a review of the role of miRNAs in lipid metabolism, with a prediction that miR-103/107 regulates human metabolic pathways

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21 June 2018

The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.

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21 June 2018

Complex translational regulation of BACE1 involves upstream AUGs and stimulatory elements within the 5' untranslated region

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21 June 2018

miR-181a is an intrinsic modulator of T cell sensitivity and selection

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21 June 2018

Characterization of microRNA expression levels and their biological correlates in human cancer cell lines

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21 June 2018

microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder

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21 June 2018

A microRNA signature of hypoxia

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21 June 2018

Genetic and pharmacological basis for therapeutic inhibition of beta- and gamma-secretases in mouse models of Alzheimer's memory deficits.

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Progress toward the discovery and development of efficacious BACE inhibitors

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Disease-modifying therapies in Alzheimer's disease: how far have we come?

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21 June 2018

A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure

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21 June 2018

A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes

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21 June 2018

BACE1 and presenilin: two unusual aspartyl proteases involved in Alzheimer's disease

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21 June 2018

Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease

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21 June 2018

BACE1 gene promoter is differentially regulated: detection of a novel promoter region for its cell type-specific regulation

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Systematic identification of microRNA functions by combining target prediction and expression profiling

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Control of APP processing and Abeta generation level by BACE1 enzymatic activity and transcription

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RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain

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Protease inhibitors as potential disease-modifying therapeutics for Alzheimer's disease

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Extensive modulation of a set of microRNAs in primary glioblastoma

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21 June 2018

Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron

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Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes

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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

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21 June 2018

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21 June 2018

miRNP:mRNA association in polyribosomes in a human neuronal cell line.

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21 June 2018

Prediction of mammalian microRNA targets

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21 June 2018

The microRNA world: small is mighty

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21 June 2018

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

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Expression of beta-secretase mRNA in transgenic Tg2576 mouse brain with Alzheimer plaque pathology

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21 June 2018

Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties

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21 June 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

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21 June 2018

Post-transcriptional contribution of a cAMP-dependent pathway to the formation of alpha- and beta/gamma-secretases-derived products of beta APP maturation in human cells expressing wild-type and Swedish mutated beta APP.

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21 June 2018

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30 October 2018

A new role for microRNA pathways: modulation of degeneration induced by pathogenic human disease proteins.

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MicroRNA responses to cellular stress.

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MicroRNA pathways modulate polyglutamine-induced neurodegeneration.

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30 October 2018

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30 October 2018

Intronic microRNAs

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30 October 2018

Beta-secretase (BACE) and GSK-3 mRNA levels in Alzheimer's disease

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Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

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30 October 2018

"Preclinical" AD revisited: neuropathology of cognitively normal older adults.

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30 October 2018

Sequestration of RNA in Alzheimer's disease neurofibrillary tangles and senile plaques.

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30 October 2018

MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors Are Associated With Distinctive Pathologic Features and Clinical Behavior

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30 October 2018

Molecular biology. miRNAs in neurodegeneration

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12 December 2020

based on heuristic

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Detection of microRNAs and assays to monitor microRNA activities in vivo and in vitro

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12 December 2020

based on heuristic

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Identifiers

10.1523/JNEUROSCI.5065-07.2008

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18234899%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PMC publication ID

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PMC publication ID

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1 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18234899%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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