Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense (Q33694792)

28 July 2017

title

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense (English)

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28 July 2017

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Heiko Horn

13

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Eduardo J Villablanca

Eduardo J Villablanca

7

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Ta-Chiang Liu

Ta-Chiang Liu

9

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Herbert W. Virgin

21

Herbert W Virgin

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28 July 2017

20

Mark J Daly

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28 July 2017

Thaddeus S. Stappenbeck

23

Thaddeus S Stappenbeck

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28 July 2017

15

Omer H Yilmaz

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28 July 2017

24

Ramnik J Xavier

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28 July 2017

22

Stuart L Schreiber

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28 July 2017

Kara G Lassen

1

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28 July 2017

Petric Kuballa

2

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28 July 2017

Kara L Conway

3

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28 July 2017

Khushbu K Patel

4

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28 July 2017

Christine E Becker

5

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28 July 2017

Joanna M Peloquin

6

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28 July 2017

Jason M Norman

8

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28 July 2017

Robert J Heath

10

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28 July 2017

Morgan L Becker

11

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Lola Fagbami

12

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Johnathan Mercer

14

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Jacob D Jaffe

16

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28 July 2017

Alykhan F Shamji

17

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28 July 2017

Atul K Bhan

18

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28 July 2017

Steven A Carr

19

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28 July 2017

language of work or name

English

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publication date

12 May 2014

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Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

published in

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28 July 2017

volume

111

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28 July 2017

issue

21

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28 July 2017

page(s)

7741-7746

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NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion

28 July 2017

cites work

1 reference

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A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3.

21 June 2018

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Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

21 June 2018

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Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules

21 June 2018

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Paneth cells as a site of origin for intestinal inflammation.

21 June 2018

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Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease.

21 June 2018

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Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection

21 June 2018

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Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism

21 June 2018

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A genome-wide siRNA screen reveals positive and negative regulators of the NOD2 and NF-κB signaling pathways.

21 June 2018

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The LRR and RING domain protein LRSAM1 is an E3 ligase crucial for ubiquitin-dependent autophagy of intracellular Salmonella Typhimurium

21 June 2018

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Complex roles of caspases in the pathogenesis of inflammatory bowel disease

21 June 2018

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Autophagy and intestinal homeostasis

21 June 2018

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Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

21 June 2018

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A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

21 June 2018

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Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells

21 June 2018

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Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

21 June 2018

1 reference

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Image-based genome-wide siRNA screen identifies selective autophagy factors

21 June 2018

1 reference

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Genetics and pathogenesis of inflammatory bowel disease

21 June 2018

1 reference

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Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation

21 June 2018

1 reference

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Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

21 June 2018

1 reference

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Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

21 June 2018

1 reference

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Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

21 June 2018

1 reference

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Network organization of the human autophagy system

21 June 2018

1 reference

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NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

21 June 2018

1 reference

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Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

21 June 2018

1 reference

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Differential involvement of Atg16L1 in Crohn disease and canonical autophagy: analysis of the organization of the Atg16L1 complex in fibroblasts

21 June 2018

1 reference

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A novel hybrid yeast-human network analysis reveals an essential role for FNBP1L in antibacterial autophagy

21 June 2018

1 reference

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Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant

21 June 2018

1 reference

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A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

21 June 2018

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Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

21 June 2018

1 reference

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Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini

21 June 2018

1 reference

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Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040621

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040621

Cloning and analysis of human Apg16L

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040621

Escape of intracellular Shigella from autophagy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040621

Conventional CD4+ T cells regulate IL-22-producing intestinal innate lymphoid cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040621

Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24821797

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1407001111

1 reference

28 July 2017

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28 July 2017

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