Clinical outcomes and correlates of TP53 mutations and cancer (Q33693838)

28 July 2017

1 reference

title

Clinical outcomes and correlates of TP53 mutations and cancer (English)

1 reference

28 July 2017

Ana I Robles

1

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28 July 2017

Curtis C Harris

series ordinal

2

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28 July 2017

publication date

1 March 2010

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Cold Spring Harbor Perspectives in Biology

28 July 2017

published in

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28 July 2017

volume

2

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28 July 2017

issue

3

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28 July 2017

page(s)

a001016

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p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence

28 July 2017

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Somatic mutations affect key pathways in lung adenocarcinoma

28 July 2018

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Myeloid cell differentiation arrest by miR-125b-1 in myelodysplastic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation

28 July 2018

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Recent advances in p53 research: an interdisciplinary perspective.

28 July 2018

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A microRNA DNA methylation signature for human cancer metastasis

28 July 2018

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Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study.

28 July 2018

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KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab.

28 July 2018

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TP53 mutations and survival in squamous-cell carcinoma of the head and neck.

28 July 2018

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American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer

28 July 2018

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Inflammation and cancer: an ancient link with novel potentials.

28 July 2018

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Prognostic value of abnormal p53 expression in locally advanced prostate cancer treated with androgen deprivation and radiotherapy: a study based on RTOG 9202

28 July 2018

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Aristolochic acid and the etiology of endemic (Balkan) nephropathy

28 July 2018

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A microRNA component of the p53 tumour suppressor network

28 July 2018

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Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

28 July 2018

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Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

28 July 2018

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TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer

28 July 2018

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Transcription regulation by mutant p53.

28 July 2018

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TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer

28 July 2018

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Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen

28 July 2018

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An overview of prognostic factors for long-term survivors of breast cancer

28 July 2018

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Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

28 July 2018

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Expression of p53 isoforms in squamous cell carcinoma of the head and neck

28 July 2018

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Quantitative detection of p53 mutations in plasma DNA from tobacco smokers

28 July 2018

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MicroRNA-cancer connection: the beginning of a new tale

28 July 2018

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The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer

28 July 2018

1 reference

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The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: influence of tumor site, type of mutation, and adjuvant treatment

28 July 2018

1 reference

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p53 isoforms can regulate p53 transcriptional activity.

28 July 2018

1 reference

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Tumour biology: senescence in premalignant tumours

28 July 2018

1 reference

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Polymorphisms in XPD and TP53 and mutation in human lung cancer

28 July 2018

1 reference

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Nitric oxide and p53 in cancer-prone chronic inflammation and oxyradical overload disease.

28 July 2018

1 reference

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TP53 mutation spectra and load: a tool for generating hypotheses on the etiology of cancer

28 July 2018

1 reference

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p53 codon 72 polymorphism and cervical neoplasia: a meta-analysis review

28 July 2018

1 reference

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Prospective detection of codon 249 mutations in plasma of hepatocellular carcinoma patients

28 July 2018

1 reference

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TP53 polymorphisms and lung cancer risk: a systematic review and meta-analysis

28 July 2018

1 reference

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Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

28 July 2018

1 reference

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Assessing TP53 status in human tumours to evaluate clinical outcome

28 July 2018

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microRNAs: tiny regulators with great potential

28 July 2018

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Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke

28 July 2018

1 reference

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Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.

28 July 2018

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Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases

28 July 2018

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Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease

28 July 2018

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Cancer-prone oxyradical overload disease

28 July 2018

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p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer

28 July 2018

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Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array

28 July 2018

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Two polymorphic variants of wild-type p53 differ biochemically and biologically

28 July 2018

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Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression

28 July 2018

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Clinical implications of the p53 tumor-suppressor gene

28 July 2018

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Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes

28 July 2018

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The p53 tumour suppressor gene

28 July 2018

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Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

28 July 2018

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A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma

28 July 2018

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p53 mutations in human cancers

28 July 2018

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Mutational hot spot in the p53 gene in human hepatocellular carcinomas

28 July 2018

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Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

28 July 2018

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Allelic frequency of a p53 polymorphism in human lung cancer

28 July 2018

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Prognostic significance of p53 codon 72 polymorphism differs with race in colorectal adenocarcinoma

28 July 2018

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Beyond Li Fraumeni Syndrome: clinical characteristics of families with p53 germline mutations

30 October 2018

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The prognostic value of TP53 mutations in chronic lymphocytic leukemia is independent of Del17p13: implications for overall survival and chemorefractoriness.

30 October 2018

1 reference

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Prognostic marker profile to assess risk in stage I-III hormone receptor-positive breast cancer patients.

30 October 2018

1 reference

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FHIT and p53 status and response to platinum-based treatment in advanced non-small cell lung cancer

30 October 2018

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Plasma DNA, microsatellite alterations, and p53 tumor mutations are associated with disease-free survival in radically resected non-small cell lung cancer patients: a study of the perugia multidisciplinary team for thoracic oncology.

30 October 2018

1 reference

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p53 tumor suppressor gene: a critical molecular target for UV induction and prevention of skin cancer

30 October 2018

1 reference

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The genomic landscapes of human breast and colorectal cancers

30 October 2018

1 reference

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Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest

30 October 2018

1 reference

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Common genetic variation in TP53 is associated with lung cancer risk and prognosis in African Americans and somatic mutations in lung tumors

30 October 2018

1 reference

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Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study.

30 October 2018

1 reference

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Penetrance of adrenocortical tumours associated with the germline TP53 R337H mutation

30 October 2018

1 reference

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249(ser) TP53 mutation in plasma DNA, hepatitis B viral infection, and risk of hepatocellular carcinoma.

30 October 2018

1 reference

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Specific TP53 and/or Ki-ras mutations as independent predictors of clinical outcome in sporadic colorectal adenocarcinomas: results of a 5-year Gruppo Oncologico dell'Italia Meridionale (GOIM) prospective study.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829964

P53 abnormalities and outcomes in colorectal cancer: a systematic review.

30 October 2018

1 reference

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Rapid and sensitive p53 alteration analysis in biopsies from lung cancer patients using a functional assay and a universal oligonucleotide array: a prospective study

30 October 2018

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Ser-249TP53 mutation in tumour and plasma DNA of hepatocellular carcinoma patients from a high incidence area in the Gambia, West Africa

30 October 2018

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p53 Codon 72 Polymorphism and Risk of Cervical Cancer

30 October 2018

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p53 mutations and survival in stage I non-small-cell lung cancer: results of a prospective study

30 October 2018

1 reference

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Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

30 October 2018

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Sensitivity of electrospray ionization mass spectrometry detection of codon 249 mutations in the p53 gene compared with RFLP.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829964

Differential association of the codon 72 p53 and GSTM1 polymorphisms on histological subtype of non-small cell lung carcinoma.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829964

Mutability of p53 hotspot codons to benzo(a)pyrene diol epoxide (BPDE) and the frequency of p53 mutations in nontumorous human lung

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829964

p53 prognostication: paradigm or paradox?

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829964

p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829964

Role of a p53 polymorphism in the development of human papillomavirus-associated cancer

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829964

Hepatocellular carcinoma: from gene to public health.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829964

p53 mutations in non-small cell lung cancer in Japan: association between mutations and smoking

30 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300207

12 December 2020

p53 and K-ras mutations in lung cancers from former and never-smoking women

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300207

12 December 2020

Hepatitis B, aflatoxin B(1), and p53 codon 249 mutation in hepatocellular carcinomas from Guangxi, People's Republic of China, and a meta-analysis of existing studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300207

12 December 2020

Discriminating functional and non-functional p53 in human tumours by p53 and MDM2 immunohistochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300207

12 December 2020

Is there a role for routine p53 testing in colorectal cancer?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300207

12 December 2020

Type of TP53 mutation and ERBB2 amplification affects survival in node-negative breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300207

12 December 2020

Using whole genome amplification (WGA) of low-volume biopsies to assess the prognostic role of EGFR, KRAS, p53, and CMET mutations in advanced-stage non-small cell lung cancer (NSCLC)

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300207

12 December 2020

TP53 DNA contact mutations are selectively associated with allelic loss and have a strong clinical impact in head and neck cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300207

12 December 2020

A comparison between p53 accumulation determined by immunohistochemistry and TP53 mutations as prognostic variables in tumours from breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300207

12 December 2020

Molecular basis of the Li-Fraumeni syndrome: an update from the French LFS families

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300207

12 December 2020

p53 null mutations undetected by immunohistochemical staining predict a poor outcome with early-stage non-small cell lung carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300207

12 December 2020

p53 gene status as a predictor of tumor response to induction chemotherapy of patients with locoregionally advanced squamous cell carcinomas of the head and neck

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300207

12 December 2020

The p53 codon 72 polymorphism and lung cancer risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300207

12 December 2020

10.1101/CSHPERSPECT.A001016

Identifiers

DOI

1 reference

28 July 2017

1 reference

28 July 2017

1 reference