Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3). (Q33636704)

28 July 2017

1 reference

title

Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3). (English)

1 reference

28 July 2017

3

Richard S Jope

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28 July 2017

1

Eléonore Beurel

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28 July 2017

Suzanne M Michalek

2

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28 July 2017

publication date

14 October 2009

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28 July 2017

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28 July 2017

volume

31

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28 July 2017

issue

1

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28 July 2017

page(s)

24-31

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Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

28 July 2017

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Inhibiting glycogen synthase kinase-3 reduces endotoxaemic acute renal failure by down-regulating inflammation and renal cell apoptosis

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Glycogen synthase kinase-3 promotes the synergistic action of interferon-gamma on lipopolysaccharide-induced IL-6 production in RAW264.7 cells

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21 June 2018

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Glycogen synthase kinase-3 negatively regulates anti-inflammatory interleukin-10 for lipopolysaccharide-induced iNOS/NO biosynthesis and RANTES production in microglial cells

21 June 2018

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Toll-like receptor-mediated production of IL-1Ra is negatively regulated by GSK3 via the MAPK ERK1/2.

21 June 2018

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Antigenic experience dictates functional role of glycogen synthase kinase-3 in human CD4+ T cell responses

21 June 2018

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Glycogen synthase kinase-3 regulates microglial migration, inflammation, and inflammation-induced neurotoxicity

21 June 2018

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21 June 2018

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IFN-beta production by TLR4-stimulated innate immune cells is negatively regulated by GSK3-beta

21 June 2018

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Glycogen synthase kinase-3beta (GSK3beta) inhibition suppresses the inflammatory response to Francisella infection and protects against tularemia in mice

21 June 2018

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Insulin reduces cerebral ischemia/reperfusion injury in the hippocampus of diabetic rats: a role for glycogen synthase kinase-3beta

21 June 2018

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21 June 2018

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Lithium prevents and ameliorates experimental autoimmune encephalomyelitis

21 June 2018

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Differential regulation of STAT family members by glycogen synthase kinase-3

21 June 2018

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Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells

21 June 2018

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Mode of action of mood stabilizers: is the arachidonic acid cascade a common target?

21 June 2018

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A shift from adaptive to innate immunity: a potential mechanism of disease progression in multiple sclerosis

21 June 2018

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Preclinical efficacy on GSK-3 inhibitors: towards a future generation of powerful drugs

21 June 2018

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Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling

21 June 2018

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Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling

21 June 2018

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Latent membrane protein 1 of EBV activates phosphatidylinositol 3-kinase to induce production of IL-10.

21 June 2018

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CIITA mediates interferon-gamma repression of collagen transcription through phosphorylation-dependent interactions with co-repressor molecules.

21 June 2018

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Activation of Toll-like receptor 4 signaling contributes to hippocampal neuronal death following global cerebral ischemia/reperfusion

21 June 2018

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Antidepressants inhibit interferon-gamma-induced microglial production of IL-6 and nitric oxide.

21 June 2018

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Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration

21 June 2018

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The pro-survival pathways of mTOR and protein kinase B target glycogen synthase kinase-3beta and nuclear factor-kappaB to foster endogenous microglial cell protection.

21 June 2018

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Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics

21 June 2018

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The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways

21 June 2018

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Microglial integrity is maintained by erythropoietin through integration of Akt and its substrates of glycogen synthase kinase-3beta, beta-catenin, and nuclear factor-kappaB.

21 June 2018

1 reference

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TcR and TcR-CD28 engagement of protein kinase B (PKB/AKT) and glycogen synthase kinase-3 (GSK-3) operates independently of guanine nucleotide exchange factor VAV-1.

21 June 2018

1 reference

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Novel anti-inflammatory role for glycogen synthase kinase-3beta in the inhibition of tumor necrosis factor-alpha- and interleukin-1beta-induced inflammatory gene expression

21 June 2018

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Glycogen synthase kinase 3- and extracellular signal-regulated kinase-dependent phosphorylation of paxillin regulates cytoskeletal rearrangement

21 June 2018

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Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B.

21 June 2018

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Reduction of experimental colitis in the rat by inhibitors of glycogen synthase kinase-3beta.

21 June 2018

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The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials

21 June 2018

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Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcription

21 June 2018

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GSK-3beta inhibitors reduce protein degradation in muscles from septic rats and in dexamethasone-treated myotubes

21 June 2018

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Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

21 June 2018

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Role for glycogen synthase kinase-3 in NK cell cytotoxicity and X-linked lymphoproliferative disease

21 June 2018

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Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity

21 June 2018

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The glamour and gloom of glycogen synthase kinase-3

21 June 2018

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Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes

21 June 2018

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GSK-3: tricks of the trade for a multi-tasking kinase

21 June 2018

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Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation

21 June 2018

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Monitoring the duration of antigen-receptor occupancy by calcineurin/glycogen-synthase-kinase-3 control of NF-AT nuclear shuttling.

21 June 2018

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Molecular targets of lithium action

21 June 2018

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Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3

21 June 2018

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Anti-bipolar therapy: mechanism of action of lithium

21 June 2018

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A molecular mechanism for the effect of lithium on development

21 June 2018

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T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3

21 June 2018

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Glycogen synthase kinase-3beta facilitates IFN-gamma-induced STAT1 activation by regulating Src homology-2 domain-containing phosphatase 2.

21 June 2018

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A role for glycogen synthase kinase-3 in antagonizing mycobacterial immune evasion by negatively regulating IL-10 induction

30 October 2018

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Glycogen synthase kinase 3 inhibition protects the heart from acute ischemia-reperfusion injury via inhibition of inflammation and apoptosis

30 October 2018

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IFN-gamma synergizes with LPS to induce nitric oxide biosynthesis through glycogen synthase kinase-3-inhibited IL-10.

30 October 2018

1 reference

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A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes.

30 October 2018

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Effects of glycogen synthase kinase-3beta inhibition on the development of cerulein-induced acute pancreatitis in mice

30 October 2018

1 reference

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beta-Catenin activity negatively regulates bacteria-induced inflammation

30 October 2018

1 reference

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Enhanced NFATc1 nuclear occupancy causes T cell activation independent of CD28 costimulation.

30 October 2018

1 reference

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Inhibition of PI3K and calcineurin suppresses chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)-dependent responses of Th2 lymphocytes to prostaglandin D(2).

30 October 2018

1 reference

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IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins.

30 October 2018

1 reference

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GSK-3beta inhibitors attenuate the organ injury/dysfunction caused by endotoxemia in the rat.

30 October 2018

1 reference

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A novel signaling pathway mediates the inhibition of CCL3/4 expression by prostaglandin E2.

30 October 2018

1 reference

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The B cell antigen receptor regulates the transcriptional activator beta-catenin via protein kinase C-mediated inhibition of glycogen synthase kinase-3.

30 October 2018

1 reference

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Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development.

30 October 2018

1 reference

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The effects of lithium on ex vivo cytokine production

30 October 2018

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Plasma levels of cytokines and soluble cytokine receptors in psychiatric patients upon hospital admission: effects of confounding factors and diagnosis.

30 October 2018

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Potentiation of antidepressants with lithium or carbamazepine in treatment-resistant depression.

30 October 2018

1 reference

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Unrestrained glycogen synthase kinase-3 beta activity leads to activated T cell death and can be inhibited by natural adjuvant

30 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836308

12 December 2020

Glycogen synthase kinase 3beta and beta-catenin are involved in the injury and repair of bronchial epithelial cells induced by scratching

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836308

12 December 2020

Glycogen Synthase Kinase-3β Inhibition Attenuates Asthma in Mice

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https://pubmed.ncbi.nlm.nih.gov/19836308

12 December 2020

The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival

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https://pubmed.ncbi.nlm.nih.gov/19836308

12 December 2020

CD28 costimulation mediates down-regulation of p27kip1 and cell cycle progression by activation of the PI3K/PKB signaling pathway in primary human T cells

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https://pubmed.ncbi.nlm.nih.gov/19836308

12 December 2020

Lithium chloride enhances survival of NZB/W lupus mice: influence of melatonin and timing of treatment

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https://pubmed.ncbi.nlm.nih.gov/19836308

12 December 2020

GLYCOGEN SYNTHASE KINASE-3?? INHIBITORS PROTECT AGAINST THE ORGAN INJURY AND DYSFUNCTION CAUSED BY HEMORRHAGE AND RESUSCITATION

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https://pubmed.ncbi.nlm.nih.gov/19836308

12 December 2020

Glycogen synthase kinase-3β inhibition attenuates the degree of arthritis caused by type II collagen in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836308

12 December 2020

Glycogen synthase kinase-3 beta inhibition reduces secondary damage in experimental spinal cord trauma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836308

12 December 2020

GSK-3 mediates differentiation and activation of proinflammatory dendritic cells

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https://pubmed.ncbi.nlm.nih.gov/19836308

12 December 2020

Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836308

12 December 2020

Glycogen synthase kinase-3beta suppresses tumor necrosis factor-alpha expression in cardiomyocytes during lipopolysaccharide stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836308

12 December 2020

Novel regulation of vascular endothelial growth factor-A (VEGF-A) by transforming growth factor (beta)1: requirement for Smads, (beta)-CATENIN, AND GSK3(beta)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836308

12 December 2020

Identifiers

DOI

10.1016/J.IT.2009.09.007

1 reference

28 July 2017

1 reference

28 July 2017

1 reference