Structural and functional characterization of the human CCR5 receptor in complex with HIV gp120 envelope glycoprotein and CD4 receptor by molecular modeling studies (Q30336122)

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scientific article published on August 29, 2003

Language	Label	Description	Also known as
English	Structural and functional characterization of the human CCR5 receptor in complex with HIV gp120 envelope glycoprotein and CD4 receptor by molecular modeling studies	scientific article published on August 29, 2003

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 June 2017

Structural and functional characterization of the human CCR5 receptor in complex with HIV gp120 envelope glycoprotein and CD4 receptor by molecular modeling studies (English)

1 reference

10.1007/S00894-003-0154-9

https://api.crossref.org/works/10.1007/S00894-003-0154-9

15 March 2024

molecular model

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517611

15 March 2024

inorganic chemistry

1 reference

10.1007/S00894-003-0154-9

https://api.crossref.org/works/10.1007/S00894-003-0154-9

15 March 2024

organic chemistry

1 reference

10.1007/S00894-003-0154-9

https://api.crossref.org/works/10.1007/S00894-003-0154-9

15 March 2024

author name string

Shuqun Liu

1

1 reference

Europe PubMed Central

PubMed publication ID

19 June 2017

Shixiu Fan

2

1 reference

Europe PubMed Central

PubMed publication ID

19 June 2017

Zhirong Sun

3

1 reference

Europe PubMed Central

PubMed publication ID

19 June 2017

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14517611

15 March 2024

publication date

29 August 2003

1 reference

Europe PubMed Central

PubMed publication ID

19 June 2017

full work available at URL

http://link.springer.com/content/pdf/10.1007/s00894-003-0154-9.pdf

Portable Document Format

1 reference

10.1007/S00894-003-0154-9

https://api.crossref.org/works/10.1007/S00894-003-0154-9

15 March 2024

http://link.springer.com/article/10.1007/s00894-003-0154-9/fulltext.html

1 reference

10.1007/S00894-003-0154-9

https://api.crossref.org/works/10.1007/S00894-003-0154-9

15 March 2024

http://link.springer.com/content/pdf/10.1007/s00894-003-0154-9

1 reference

10.1007/S00894-003-0154-9

https://api.crossref.org/works/10.1007/S00894-003-0154-9

15 March 2024

Journal of Molecular Modeling

1 reference

Europe PubMed Central

PubMed publication ID

19 June 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

19 June 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

19 June 2017

329-336

1 reference

Europe PubMed Central

PubMed publication ID

19 June 2017

describes a project that uses

molecular modelling

1 reference

based on heuristic

inferred from title

CCR5-Mediated human immunodeficiency virus entry depends on an amino-terminal gp120-binding site and on the conformational integrity of all four extracellular domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane proteins. Membrane protein structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Protein Data Bank

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple extracellular domains of CCR-5 contribute to human immunodeficiency virus type 1 entry and fusion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and function of G protein-coupled receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a major co-receptor for primary isolates of HIV-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A tyrosine-rich region in the N terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the interaction of antibodies with a conserved enzymatically deglycosylated core of the HIV type 1 envelope glycoprotein 120

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The second extracellular loop of CCR5 is the major determinant of ligand specificity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CC chemokine receptor 5-mediated signaling and HIV-1 Co-receptor activity share common structural determinants. Critical residues in the third extracellular loop support HIV-1 fusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antigenic structure of the HIV gp120 envelope glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular anatomy of CCR5 engagement by physiologic and viral chemokines and HIV-1 envelope glycoproteins: differences in primary structural requirements for RANTES, MIP-1 alpha, and vMIP-II Binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple extracellular elements of CCR5 and HIV-1 entry: dissociation from response to chemokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alanine substitutions of polar and nonpolar residues in the amino-terminal domain of CCR5 differently impair entry of macrophage- and dualtropic isolates of human immunodeficiency virus type 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00894-003-0154-9

1 reference

Europe PubMed Central

PubMed publication ID

19 June 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 June 2017

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