Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers (Q30300404)

10 October 2017

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers (English)

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10 October 2017

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16

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10 October 2017

20

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10 October 2017

25

1 reference

10 October 2017

Michal Szpak

9

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Ellen Schofield

Ellen Schofield

10

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Aaron R Quinlan

Aaron R Quinlan

5

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Oliver Burren

Oliver Burren

3

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Anshul Kundaje

Anshul Kundaje

17

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Neil M Walker

Neil M Walker

15

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Manolis Kellis

18

Manolis Kellis

1 reference

10 October 2017

19

Mark J Daly

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10 October 2017

24

John A Todd

1 reference

ORCID Public Data File 2021

10 October 2017

0 references

1 reference

Richard McIndoe

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ORCID Public Data File 2021

Helen E Stevens

14

Helen Stevens

1 reference

10 October 2017

27

Stephen S Rich

1 reference

10 October 2017

13

Mary D Fortune

1 reference

Type 1 Diabetes Genetics Consortium

10 October 2017

23

Type 1 Diabetes Genetics Consortium

1 reference

10 October 2017

6

Josyf C Mychaleckyj

1 reference

10 October 2017

11

Premanand Achuthan

1 reference

10 October 2017

Wei-Min Chen

2

1 reference

10 October 2017

Nick J Cooper

4

1 reference

10 October 2017

Emily Farber

7

1 reference

10 October 2017

Jessica K Bonnie

8

1 reference

10 October 2017

Hui Guo

12

1 reference

10 October 2017

Jason D Cooper

21

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10 October 2017

language of work or name

English

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publication date

9 March 2015

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10 October 2017

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10 October 2017

47

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10 October 2017

4

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10 October 2017

381-386

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Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C.

10 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Bayesian test for colocalisation between pairs of genetic association studies using summary statistics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

An atlas of active enhancers across human cell types and tissues

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Systematic identification of trans eQTLs as putative drivers of known disease associations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Bayesian refinement of association signals for 14 loci in 3 common diseases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Structural haplotypes and recent evolution of the human 17q21.31 region

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Circulating preproinsulin signal peptide-specific CD8 T cells restricted by the susceptibility molecule HLA-A24 are expanded at onset of type 1 diabetes and kill β-cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Population structure of Hispanics in the United States: the multi-ethnic study of atherosclerosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Metagenomics and personalized medicine

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Pervasive sharing of genetic effects in autoimmune disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

A map of human genome variation from population-scale sequencing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

P-value based analysis for shared controls design in genome-wide association studies.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Robust relationship inference in genome-wide association studies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

METAL: fast and efficient meta-analysis of genomewide association scans

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Designing and implementing sample and data collection for an international genetics study: the Type 1 Diabetes Genetics Consortium (T1DGC).

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

A generalized family-based association test for dichotomous traits

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Genome-wide scan for linkage to type 1 diabetes in 2,496 multiplex families from the Type 1 Diabetes Genetics Consortium

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Shared and distinct genetic variants in type 1 diabetes and celiac disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

PLINK: a tool set for whole-genome association and population-based linkage analyses

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Principal components analysis corrects for stratification in genome-wide association studies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Cohort profile: 1958 British birth cohort (National Child Development Study).

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Two genes encoding immune-regulatory molecules (LAG3 and IL7R) confer susceptibility to multiple sclerosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Follow-up report on the diagnosis of diabetes mellitus

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380767

Lowering the criterion for impaired fasting glucose is in order

3 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG.3245

Remapping the insulin gene/IDDM2 locus in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG.3245

Summarizing historical information on controls in clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG.3245

Bayes factors for genome-wide association studies: comparison with P-values

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG.3245

A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25751624

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.3245

1 reference

10 October 2017

1 reference

10 October 2017

PubMed publication ID

25751624

1 reference