BZIP domain-containing protein;Protein skinhead-1 CELE_T19E7.2 (Q29806605)

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protein found in Caenorhabditis elegans

SKiNhead
Protein skinhead-1;SKiNhead
Protein skinhead-1
BZIP domain-containing protein;Protein skinhead-1
skn-1

Language	Label	Description	Also known as
English	BZIP domain-containing protein;Protein skinhead-1 CELE_T19E7.2	protein found in Caenorhabditis elegans	SKiNhead Protein skinhead-1;SKiNhead Protein skinhead-1 BZIP domain-containing protein;Protein skinhead-1 skn-1

Statements

1 reference

25 May 2022

UniProt protein ID

Transcription factor, Skn-1-like, DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P34707

Basic-leucine zipper domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Basic leucine zipper domain, Maf-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Caenorhabditis elegans

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

RNA polymerase II transcription regulatory region sequence-specific DNA binding

determination method or standard

3 references

1 January 2018

Regulation of synaptic nlg-1/neuroligin abundance by the skn-1/Nrf stress response pathway protects against oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

1 January 2018

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

1 January 2018

Integration of the unfolded protein and oxidative stress responses through SKN-1/Nrf

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

protein binding

determination method or standard

2 references

1 January 2018

The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

1 January 2018

The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

Hsp70 protein binding

determination method or standard

1 reference

1 January 2018

Integration of the unfolded protein and oxidative stress responses through SKN-1/Nrf

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

determination method or standard

5 references

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

1 January 2018

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

1 January 2018

The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

1 January 2018

The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

determination method or standard

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

determination method or standard

1 reference

1 January 2018

Mitochondrial SKN-1/Nrf mediates a conserved starvation response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

endoplasmic reticulum

determination method or standard

1 reference

1 January 2018

Integration of the unfolded protein and oxidative stress responses through SKN-1/Nrf

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

biological process

response to superoxide

determination method or standard

cell fate specification

determination method or standard

1 reference

1 January 2018

Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

endodermal cell fate specification

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34707&geneProductId=UniProtKB:P34707

determination method or standard

regulation of transcription, DNA-templated

determination method or standard

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

regulation of translation

determination method or standard

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

response to oxidative stress

determination method or standard

1 reference

1 January 2018

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response

determination method or standard

1 reference

1 January 2018

Integration of the unfolded protein and oxidative stress responses through SKN-1/Nrf

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

multicellular organism development

determination method or standard

determination of adult lifespan

determination method or standard

5 references

1 January 2018

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

1 January 2018

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

1 January 2018

TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

1 January 2018

Manipulation of behavioral decline in Caenorhabditis elegans with the Rag GTPase raga-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

1 January 2018

Life-span extension by dietary restriction is mediated by NLP-7 signaling and coelomocyte endocytosis in C. elegans

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

response to heat

determination method or standard

1 reference

1 January 2018

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

embryonic pattern specification

determination method or standard

1 reference

1 January 2018

Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

positive regulation of gene expression

determination method or standard

1 reference

1 January 2018

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

mesendoderm development

determination method or standard

1 reference

1 January 2018

skn-1, a maternally expressed gene required to specify the fate of ventral blastomeres in the early C. elegans embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

embryonic digestive tract development

determination method or standard

2 references

positive regulation of transcription from RNA polymerase II promoter in response to heat stress

determination method or standard

1 reference

1 January 2018

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

positive regulation of cellular response to oxidative stress

determination method or standard

1 reference

1 January 2018

TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

negative regulation of neuron death

determination method or standard

2 references

1 January 2018

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

1 January 2018

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

response to paraquat

determination method or standard

1 reference

1 January 2018

Life-span extension by dietary restriction is mediated by NLP-7 signaling and coelomocyte endocytosis in C. elegans

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

positive regulation of cellular response to manganese ion

determination method or standard

2 references

1 January 2018

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

1 January 2018

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination method or standard

Basic-leucine zipper domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P34707

Basic leucine zipper domain, Maf-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P34707

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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