The emerging shape of the ESCRT machinery (Q29620787)

Europe PubMed Central

title

The emerging shape of the ESCRT machinery (English)

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17450176

30 April 2017

author name string

Williams RL

series ordinal

1

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30 April 2017

Urbé S

series ordinal

2

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17450176

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17450176

30 April 2017

language of work or name

1 reference

30 April 2017

publication date

May 2007

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17450176

Nature Reviews Molecular Cell Biology

30 April 2017

published in

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17450176

30 April 2017

volume

8

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17450176

30 April 2017

issue

5

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30 April 2017

page(s)

355-68

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Ultrastructural analysis of ESCRT proteins suggests a role for endosome-associated tubular-vesicular membranes in ESCRT function

30 April 2017

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The multiple personalities of Alix

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Endosomal and non-endosomal functions of ESCRT proteins

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Membrane Transport: A Coat for Ubiquitin

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Hrs function: viruses provide the clue

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The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting.

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Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant

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Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila

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Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis

31 March 2020

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Effects of deficiencies of STAMs and Hrs, mammalian class E Vps proteins, on receptor downregulation.

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Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation

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Endosomal dynamics of Met determine signaling output

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STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes

31 March 2020

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Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

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Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate

31 March 2020

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Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

31 March 2020

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The UIM domain of Hrs couples receptor sorting to vesicle formation

31 March 2020

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Endosomal compartmentalization in three dimensions: Implications for membrane fusion

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Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomes

31 March 2020

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Activation of the endosome-associated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machinery

31 March 2020

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Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains

31 March 2020

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Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth

31 March 2020

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A hrs binding protein having a Src homology 3 domain is involved in intracellular degradation of growth factors and their receptors

31 March 2020

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Hrs, a mammalian master molecule in vesicular transport and protein sorting, suppresses the degradation of ESCRT proteins signal transducing adaptor molecule 1 and 2

31 March 2020

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Association with Hrs is required for the early endosomal localization, stability, and function of STAM

31 March 2020

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Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transduction

31 March 2020

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Essential role of Hrs in a recycling mechanism mediating functional resensitization of cell signaling.

31 March 2020

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STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif

31 March 2020

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Crystal structure of a phosphatidylinositol 3-phosphate-specific membrane-targeting motif, the FYVE domain of Vps27p

31 March 2020

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Multivalent endosome targeting by homodimeric EEA1

31 March 2020

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Phosphatidylinositol 3-phosphate induces the membrane penetration of the FYVE domains of Vps27p and Hrs.

31 March 2020

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The endosome-associated protein Hrs is hexameric and controls cargo sorting as a "master molecule".

31 March 2020

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TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation

31 March 2020

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Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes

31 March 2020

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Structure and functional interactions of the Tsg101 UEV domain

31 March 2020

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HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein.

31 March 2020

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Vps27 recruits ESCRT machinery to endosomes during MVB sorting

31 March 2020

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Vps27-Hse1 and ESCRT-I complexes cooperate to increase efficiency of sorting ubiquitinated proteins at the endosome.

31 March 2020

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Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.

31 March 2020

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Mvb12 is a novel member of ESCRT-I involved in cargo selection by the multivesicular body pathway

31 March 2020

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New component of ESCRT-I regulates endosomal sorting complex assembly

31 March 2020

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Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12

31 March 2020

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Structural insight into the ESCRT-I/-II link and its role in MVB trafficking

31 March 2020

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The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation

31 March 2020

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TSG101/mammalian VPS23 and mammalian VPS28 interact directly and are recruited to VPS4-induced endosomes

31 March 2020

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Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding

31 March 2020

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The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding

31 March 2020

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Depletion of TSG101 forms a mammalian "Class E" compartment: a multicisternal early endosome with multiple sorting defects.

31 March 2020

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Structural and functional organization of the ESCRT-I trafficking complex

31 March 2020

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ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes

31 March 2020

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Structural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins.

31 March 2020

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Ubiquitin recognition by the human TSG101 protein

31 March 2020

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The Crystal Structure of the C-Terminal Domain of Vps28 Reveals a Conserved Surface Required for Vps20 Recruitment

31 March 2020

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Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release

31 March 2020

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Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body

31 March 2020

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ESCRT-II, an endosome-associated complex required for protein sorting: crystal structure and interactions with ESCRT-III and membranes.

31 March 2020

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Structure of the ESCRT-II endosomal trafficking complex

31 March 2020

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Crystal structure of subunit VPS25 of the endosomal trafficking complex ESCRT-II

31 March 2020

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Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRT-II component EAP20 and regulates endosomal cargo sorting

31 March 2020

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Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain

31 March 2020

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Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain

31 March 2020

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Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain

31 March 2020

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Ubiquitin interactions of NZF zinc fingers

31 March 2020

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Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila

31 March 2020

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vps25 mosaics display non-autonomous cell survival and overgrowth, and autonomous apoptosis

31 March 2020

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The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking

31 March 2020

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Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth

31 March 2020

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Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII

31 March 2020

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Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting

31 March 2020

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The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways

31 March 2020

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A family of small coiled-coil-forming proteins functioning at the late endosome in yeast

31 March 2020

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Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomes

31 March 2020

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CHMP7, a novel ESCRT-III-related protein, associates with CHMP4b and functions in the endosomal sorting pathway

31 March 2020

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Structural basis for budding by the ESCRT-III factor CHMP3

31 March 2020

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Release of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 budding

31 March 2020

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Interaction of AMSH with ESCRT-III and deubiquitination of endosomal cargo

31 March 2020

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AMSH is an endosome-associated ubiquitin isopeptidase

31 March 2020

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Structural and mechanistic studies of VPS4 proteins

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The Protein Network of HIV Budding

31 March 2020

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A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex

31 March 2020

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Protein-protein interactions of ESCRT complexes in the yeast Saccharomyces cerevisiae.

31 March 2020

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Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins

31 March 2020

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Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1

31 March 2020

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Ent5p is required with Ent3p and Vps27p for ubiquitin-dependent protein sorting into the multivesicular body.

31 March 2020

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Identification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalization

31 March 2020

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AMSH, an ESCRT-III associated enzyme, deubiquitinates cargo on MVB/late endosomes

31 March 2020

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Structure and ESCRT-III protein interactions of the MIT domain of human VPS4A.

31 March 2020

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The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells

31 March 2020

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Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

31 March 2020

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The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.

31 March 2020

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CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis

31 March 2020

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Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1

31 March 2020

1 reference

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ATPase-deficient hVPS4 impairs formation of internal endosomal vesicles and stabilizes bilayered clathrin coats on endosomal vacuoles

31 March 2020

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Mammalian cells express two VPS4 proteins both of which are involved in intracellular protein trafficking

31 March 2020

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The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function

31 March 2020

1 reference

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A dominant negative form of the AAA ATPase SKD1/VPS4 impairs membrane trafficking out of endosomal/lysosomal compartments: class E vps phenotype in mammalian cells

31 March 2020

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Central pore residues mediate the p97/VCP activity required for ERAD

31 March 2020

1 reference

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Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B

31 March 2020

1 reference

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Vps20p and Vta1p interact with Vps4p and function in multivesicular body sorting and endosomal transport in Saccharomyces cerevisiae.

31 March 2020

1 reference

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Characterization of Vta1p, a class E Vps protein in Saccharomyces cerevisiae

31 March 2020

1 reference

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Bro1 coordinates deubiquitination in the multivesicular body pathway by recruiting Doa4 to endosomes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM2162

Mechanism and function of deubiquitinating enzymes

31 March 2020

1 reference

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Uptake of the ATP-binding cassette (ABC) transporter Ste6 into the yeast vacuole is blocked in the doa4 Mutant

31 March 2020

1 reference

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Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting

31 March 2020

1 reference

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Deubiquitination step in the endocytic pathway of yeast plasma membrane proteins: crucial role of Doa4p ubiquitin isopeptidase.

31 March 2020

1 reference

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Structural basis for endosomal targeting by the Bro1 domain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM2162

Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8)

31 March 2020

1 reference

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Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde

31 March 2020

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A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKP

31 March 2020

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Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM2162

Hse1, a component of the yeast Hrs-STAM ubiquitin-sorting complex, associates with ubiquitin peptidases and a ligase to control sorting efficiency into multivesicular bodies

31 March 2020

1 reference

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The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

31 March 2020

1 reference

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A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes

31 March 2020

1 reference

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UBPY-mediated epidermal growth factor receptor (EGFR) de-ubiquitination promotes EGFR degradation

31 March 2020

1 reference

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The deubiquitinating enzyme Ubp2 modulates Rsp5-dependent Lys63-linked polyubiquitin conjugates in Saccharomyces cerevisiae

31 March 2020

1 reference

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Rab conversion as a mechanism of progression from early to late endosomes

31 March 2020

1 reference

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Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors

31 March 2020

1 reference

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EGF stimulates annexin 1-dependent inward vesiculation in a multivesicular endosome subpopulation

31 March 2020

1 reference

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Genetic structure and evolution of the Vps25 family, a yeast ESCRT-II component

31 March 2020

1 reference

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The Plasmodium falciparum Vps4 homolog mediates multivesicular body formation

31 March 2020

1 reference

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Structure and Ubiquitin Binding of the Ubiquitin-interacting Motif

31 March 2020

1 reference

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Ubiquitin binding in endocytosis--how tight should it be and where does it happen?

31 March 2020

1 reference

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Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting

31 March 2020

1 reference

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Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation

31 March 2020

1 reference

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Recognizing phosphatidylinositol 3-phosphate.

31 March 2020

1 reference

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Role of LBPA and Alix in multivesicular liposome formation and endosome organization

31 March 2020

1 reference

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Gene silencing reveals a specific function of hVps34 phosphatidylinositol 3-kinase in late versus early endosomes

31 March 2020

1 reference

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Human VPS34 is required for internal vesicle formation within multivesicular endosomes

31 March 2020

1 reference

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The deletion of CaVPS34 in the human pathogenic yeast Candida albicans causes defects in vesicle-mediated protein sorting and nuclear segregation

31 March 2020

1 reference

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17450176

31 March 2020

Identifiers

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1019007087

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17450176

PubMed publication ID

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017