Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice (Q28594763)

31 January 2017

title

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice (English)

1 reference

Perforin 1 (pore forming protein)

31 January 2017

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GOA release 2020-03-11

8

R. M. Zinkernagel

1 reference

31 January 2017

D. Kägi

1

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31 January 2017

B. Ledermann

2

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31 January 2017

K. Bürki

3

1 reference

31 January 2017

P. Seiler

4

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31 January 2017

B. Odermatt

5

1 reference

31 January 2017

K. J. Olsen

6

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31 January 2017

E. R. Podack

7

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31 January 2017

H. Hengartner

9

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31 January 2017

language of work or name

English

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publication date

5 May 1994

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31 January 2017

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31 January 2017

volume

369

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31 January 2017

issue

6475

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31 January 2017

page(s)

31–37

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Recovery from acute virus infection. Role of cytotoxic T lymphocytes in the elimination of lymphocytic choriomeningitis virus from spleens of mice

31 January 2017

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Internal Disintegration Model of Cytotoxic Lymphocyte-Induced Target Damage

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Mechanism of lymphocyte-mediated cytotoxicity

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Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules

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Expression of perforin in murine natural killer cells and cytotoxic T lymphocytes in vivo

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Detection of perforin and granzyme A mRNA in infiltrating cells during infection of mice with lymphocytic choriomeningitis virus

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7 January 2021

A high proportion of T lymphocytes that infiltrate H-2-incompatible heart allografts in vivo express genes encoding cytotoxic cell-specific serine proteases, but do not express the MEL-14-defined lymph node homing receptor.

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Perforin-mediated myocardial damage in acute myocarditis

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Genomic organization of the mouse pore-forming protein (perforin) gene and localization to chromosome 10. Similarities to and differences from C9.

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T cell-mediated hepatitis in mice infected with lymphocytic choriomeningitis virus. Liver cell destruction by H-2 class I-restricted virus-specific cytotoxic T cells as a physiological correlate of the 51Cr-release assay?

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