Wnt5a regulates distinct signalling pathways by binding to Frizzled2 (Q28588878)

31 January 2017

title

Wnt5a regulates distinct signalling pathways by binding to Frizzled2 (English)

1 reference

Wingless-type MMTV integration site family, member 3A

31 January 2017

main subject

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Wingless-type MMTV integration site family, member 5A

GOA release 2020-03-11

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Low density lipoprotein receptor-related protein 6

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Akira Sato

1

1 reference

31 January 2017

Hideki Yamamoto

2

1 reference

31 January 2017

Hiroshi Sakane

3

1 reference

31 January 2017

Hirofumi Koyama

4

1 reference

31 January 2017

Akira Kikuchi

5

1 reference

31 January 2017

language of work or name

English

0 references

publication date

6 January 2010

1 reference

31 January 2017

1 reference

31 January 2017

volume

29

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31 January 2017

issue

1

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31 January 2017

page(s)

41–54

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The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo

31 January 2017

cites work

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Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a

17 March 2017

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Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation

17 March 2017

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Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling

17 March 2017

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Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin

17 March 2017

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Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors

17 March 2017

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Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context

17 March 2017

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Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction

17 March 2017

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Wnt3a links left-right determination with segmentation and anteroposterior axis elongation

17 March 2017

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Wnt-independent activation of beta-catenin mediated by a Dkk1-Fz5 fusion protein

17 March 2017

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17 March 2017

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17 March 2017

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Wnt activates the Tak1/Nemo-like kinase pathway

17 March 2017

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17 March 2017

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Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4

17 March 2017

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Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation

17 March 2017

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The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway

17 March 2017

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Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation

17 March 2017

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The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling

17 March 2017

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Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

17 March 2017

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Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors

17 March 2017

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A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo

17 March 2017

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Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos

17 March 2017

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A member of the Frizzled protein family mediating axis induction by Wnt-5A

17 March 2017

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Wnt-3a regulates somite and tailbud formation in the mouse embryo

17 March 2017

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Regulated portals of entry into the cell

17 March 2017

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Secreted antagonists of the Wnt signalling pathway

7 April 2017

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A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

7 April 2017

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A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling

7 April 2017

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Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors

7 April 2017

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Selective activation mechanisms of Wnt signaling pathways

7 April 2017

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Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways

29 September 2017

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Ror receptor tyrosine kinases: orphans no more

29 September 2017

1 reference

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Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation

29 September 2017

1 reference

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Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration

29 September 2017

1 reference

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Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808370

Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808370

Tumor formation due to abnormalities in the beta-catenin-independent pathway of Wnt signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808370

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808370

Inhibition of endocytosis blocks Wnt signalling to beta-catenin by promoting dishevelled degradation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808370

Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808370

Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808370

Structure-function analysis of Frizzleds

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808370

Wnt-3a and Dvl induce neurite retraction by activating Rho-associated kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808370

Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808370

Arresting developments in heptahelical receptor signaling and regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808370

Role of the ENTH domain in phosphatidylinositol-4,5-bisphosphate binding and endocytosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808370

Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808370

Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808370

3 June 2018

Identifiers

DOI

10.1038/EMBOJ.2009.322

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