Role of the glyoxalase system in astrocyte-mediated neuroprotection (Q28588521)

31 January 2017

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18 January 2020

title

Role of the glyoxalase system in astrocyte-mediated neuroprotection (English)

2 references

31 January 2017

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Hydroxyacyl glutathione hydrolase

18 January 2020

main subject

astrocyte

0 references

1 reference

GOA release 2020-03-11

Glyoxalase 1

1 reference

GOA release 2020-03-11

author

Pierre Magistretti

5

1 reference

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18 January 2020

Igor Allaman

6

1 reference

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18 January 2020

author name string

Mireille Bélanger

1

2 references

31 January 2017

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18 January 2020

Jiangyan Yang

2

2 references

31 January 2017

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18 January 2020

Jean-Marie Petit

3

2 references

31 January 2017

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18 January 2020

Thierry Laroche

4

2 references

31 January 2017

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18 January 2020

language of work or name

English

0 references

publication date

1 December 2011

1 reference

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18 January 2020

published in

Journal of Neuroscience

2 references

31 January 2017

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18 January 2020

volume

31

2 references

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18 January 2020

issue

50

2 references

31 January 2017

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18 January 2020

page(s)

18338-18352

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Neurotoxicity of methylglyoxal and 3-deoxyglucosone on cultured cortical neurons: synergism between glycation and oxidative stress, possibly involved in neurodegenerative diseases

18 January 2020

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1 reference

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12 December 2020

Glyoxalase I is a novel nitric-oxide-responsive protein

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12 December 2020

Methylglyoxal in living organisms: chemistry, biochemistry, toxicology and biological implications

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Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease

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12 December 2020

Metabolism and functions of glutathione in brain.

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12 December 2020

Advanced glycation end products, their receptors and diabetic angiopathy

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12 December 2020

Advanced glycation endproducts co-localize with inducible nitric oxide synthase in Alzheimer's disease

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12 December 2020

Troglitazone selectively inhibits glyoxalase I gene expression

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12 December 2020

Different responses of astrocytes and neurons to nitric oxide: the role of glycolytically generated ATP in astrocyte protection.

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12 December 2020

Amyloid beta-peptide decreases neuronal glucose uptake despite causing increase in GLUT3 mRNA transcription and GLUT3 translocation to the plasma membrane.

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12 December 2020

Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray

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12 December 2020

Increased formation of methylglyoxal and protein glycation, oxidation and nitrosation in triosephosphate isomerase deficiency

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12 December 2020

Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway.

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12 December 2020

Glucocorticoids modulate neurotransmitter-induced glycogen metabolism in cultured cortical astrocytes.

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12 December 2020

Role for glyoxalase I in Alzheimer's disease.

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12 December 2020

Neural activity triggers neuronal oxidative metabolism followed by astrocytic glycolysis.

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12 December 2020

Age- and stage-dependent accumulation of advanced glycation end products in intracellular deposits in normal and Alzheimer's disease brains.

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12 December 2020

Glutamate mediates acute glucose transport inhibition in hippocampal neurons.

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12 December 2020

Conventional antibody against Nepsilon-(carboxymethyl)lysine (CML) shows cross-reaction to Nepsilon-(carboxyethyl)lysine (CEL): immunochemical quantification of CML with a specific antibody

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12 December 2020

Age-dependent changes of glyoxalase I expression in human brain

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12 December 2020

Methylglyoxal, glyoxal, and their detoxification in Alzheimer's disease

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12 December 2020

Age- and stage-dependent glyoxalase I expression and its activity in normal and Alzheimer's disease brains

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12 December 2020

Glyoxalase I is critical for human retinal capillary pericyte survival under hyperglycemic conditions

1 reference

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12 December 2020

Methylglyoxal causes strong weakening of detoxifying capacity and apoptotic cell death in rat hippocampal neurons.

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12 December 2020

Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy.

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12 December 2020

Usefulness of antibodies for evaluating the biological significance of AGEs

1 reference

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12 December 2020

The tandem of free radicals and methylglyoxal

1 reference

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12 December 2020

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

1 reference

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12 December 2020

Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans

1 reference

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12 December 2020

Modulation of astrocytic metabolic phenotype by proinflammatory cytokines

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12 December 2020

Methylglyoxal and glucose metabolism: a historical perspective and future avenues for research

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12 December 2020

Protein and nucleotide damage by glyoxal and methylglyoxal in physiological systems--role in ageing and disease

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12 December 2020

Analysis of Methylglyoxal Metabolism in CHO Cells Grown in Culture

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12 December 2020

Astroglial metabolic networks sustain hippocampal synaptic transmission

1 reference

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12 December 2020

The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration

1 reference

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12 December 2020

Glyoxalase I overexpression ameliorates renal ischemia-reperfusion injury in rats

1 reference

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12 December 2020

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.

1 reference

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12 December 2020

The Nrf2-ARE cytoprotective pathway in astrocytes

1 reference

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12 December 2020

Lentiviral and adeno-associated vector-based therapy for motor neuron disease through RNAi

1 reference

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12 December 2020

Role of glutamate in neuron-glia metabolic coupling

1 reference

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12 December 2020

C. elegans as model for the study of high glucose- mediated life span reduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

The role of astroglia in neuroprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

Amyloid-beta aggregates cause alterations of astrocytic metabolic phenotype: impact on neuronal viability

1 reference

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12 December 2020

A study of D-lactate and extracellular methylglyoxal production in lactate re-utilizing CHO cultures

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12 December 2020

Tenuigenin protects cultured hippocampal neurons against methylglyoxal-induced neurotoxicity

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12 December 2020

Advanced glycation endproducts and their pathogenic roles in neurological disorders

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12 December 2020

Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome

1 reference

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12 December 2020

Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation end products and oxidative stress in diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

Predominant enhancement of glucose uptake in astrocytes versus neurons during activation of the somatosensory cortex

1 reference

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12 December 2020

Differential effects of pro- and anti-inflammatory cytokines alone or in combinations on the metabolic profile of astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

Astrocyte-neuron metabolic relationships: for better and for worse

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

Inhibition of proliferation of human promyelocytic leukaemia HL60 cells by S-d-lactoylglutathione in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

Spectrophotometric determination of oxidized and reduced pyridine nucleotides in erythrocytes using a single extraction procedure

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

D- and L-lactate catabolism to CO2 in rat tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

Glyoxalase I in detoxification: studies using a glyoxalase I transfectant cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

The glyoxalase system in health and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

Cellular mechanisms of brain energy metabolism. Relevance to functional brain imaging and to neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

Method for determination of free intracellular and extracellular methylglyoxal in animal cells grown in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

Evidence of high levels of methylglyoxal in cultured Chinese hamster ovary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171037

12 December 2020

10.1523/JNEUROSCI.1249-11.2011

Identifiers

DOI

2 references

31 January 2017

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18 January 2020

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18 January 2020

2 references

31 January 2017