The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2 (Q28576814)

31 January 2017

title

The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2 (English)

1 reference

31 January 2017

main subject

protein ubiquitination

1 reference

Zhimin Lu

1

1 reference

31 January 2017

Shuichan Xu

2

1 reference

31 January 2017

Claudio Joazeiro

3

1 reference

31 January 2017

Melanie H. Cobb

4

1 reference

31 January 2017

Tony Hunter

5

1 reference

31 January 2017

language of work or name

1 reference

1 May 2002

1 reference

31 January 2017

1 reference

31 January 2017

volume

9

1 reference

31 January 2017

issue

5

1 reference

31 January 2017

page(s)

945–956

1 reference

Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family

31 January 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

The PHD finger: implications for chromatin-mediated transcriptional regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

The U box is a modified RING finger — a common domain in ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

The RING finger domain: a recent example of a sequence-structure family

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Catalytic Activation of the Phosphatase MKP-3 by ERK2 Mitogen-Activated Protein Kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Solution structure of the PHD domain from the KAP-1 corepressor: structural determinants for PHD, RING and LIM zinc-binding domains

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Mammalian MAP kinase signalling cascades

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

1 reference

7 January 2021

A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Serine/threonine protein kinases and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Signal transduction by the JNK group of MAP kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Regulation of the activity of MEK kinase 1 (MEKK1) by autophosphorylation within the kinase activation domain

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

The RING finger. A novel protein sequence motif related to the zinc finger.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Mutations in transcriptional regulator ATRX establish the functional significance of a PHD-like domain

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Ubiquitin-dependent degradation of active Src.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Ubiquitin-mediated degradation of active Src tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

U box proteins as a new family of ubiquitin-protein ligases

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Ubiquitin-dependent protein degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Membrane-bound human 3beta-hydroxysteroid dehydrogenase: overexpression with His-tag using a baculovirus system and single-step purification

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Modifying chromatin and concepts of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Biochemistry. Ubiquitination--more than two to tango

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

A proteolytic pathway that recognizes ubiquitin as a degradation signal

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

MEKK1 binds raf-1 and the ERK2 cascade components

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Reconstitution of mitogen-activated protein kinase phosphorylation cascades in bacteria. Efficient synthesis of active protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Characterization of apoptosis induced by sorbitol: a unique system for the detection of antiapoptotic activities of viruses.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

The APC11 RING-H2 finger mediates E2-dependent ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Biochemical analyses of the AF10 protein: the extended LAP/PHD-finger mediates oligomerisation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

A novel human gene, WSTF, is deleted in Williams syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Activation of protein kinase C triggers its ubiquitination and degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

MEK inhibition enhances paclitaxel-induced tumor apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Structure of the PHD zinc finger from human Williams-Beuren syndrome transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

AIRE encodes a nuclear protein co-localizing with cytoskeletal filaments: altered sub-cellular distribution of mutants lacking the PHD zinc fingers

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

The leukemia-associated-protein (LAP) domain, a cysteine-rich motif, is present in a wide range of proteins, including MLL, AF10, and MLLT6 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Identification of a novel mutation in the autoimmune regulator (AIRE-1) gene in a French family with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

A conserved docking motif in MAP kinases common to substrates, activators and regulators

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

The Ras/phosphatidylinositol 3-kinase and Ras/ERK pathways function as independent survival modules each of which inhibits a distinct apoptotic signaling pathway in sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900519-1

7 January 2021

10.1016/S1097-2765(02)00519-1

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017