Annexin A2 (Q2851537)

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mammalian protein found in Homo sapiens
  • placental anticoagulant protein IV
  • epididymis secretory sperm binding protein
  • annexin A2
  • protein I
  • calpactin I heavy chain
  • calpactin I heavy polypeptide
  • calpactin-1 heavy chain
  • PAP-IV
  • lipocortin II
  • annexin-2
  • ANXA2
  • epididymis secretory protein Li 270
  • chromobindin 8
  • annexin II
  • p36
  • Chromobindin-8
  • ANXA2 protein, human
edit
Language Label Description Also known as
English
Annexin A2
mammalian protein found in Homo sapiens
  • placental anticoagulant protein IV
  • epididymis secretory sperm binding protein
  • annexin A2
  • protein I
  • calpactin I heavy chain
  • calpactin I heavy polypeptide
  • calpactin-1 heavy chain
  • PAP-IV
  • lipocortin II
  • annexin-2
  • ANXA2
  • epididymis secretory protein Li 270
  • chromobindin 8
  • annexin II
  • p36
  • Chromobindin-8
  • ANXA2 protein, human

Statements

molecular function
protein binding
determination method or standard
IPI
15 references
retrieved
17 October 2017
stated in
Cochlin induced TREK-1 co-expression and annexin A2 secretion: role in trabecular meshwork cell elongation and motility
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
17 October 2017
stated in
S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
17 October 2017
stated in
CEACAM1, a cell-cell adhesion molecule, directly associates with annexin II in a three-dimensional model of mammary morphogenesis
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
17 October 2017
stated in
Angiogenin interacts with the plasminogen activation system at the cell surface of breast cancer cells to regulate plasmin formation and cell migration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
17 October 2017
stated in
Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
17 October 2017
stated in
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
17 October 2017
stated in
Annexin A2 is a C-terminal PCSK9-binding protein that regulates endogenous low density lipoprotein receptor levels
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
17 October 2017
stated in
N-Terminal Polypeptide of Annexin A2 Decreases Infection of Mycoplasma hyorhinis to Gastric Cancer Cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
17 October 2017
stated in
Annexin A2 is involved in the formation of hepatitis C virus replication complex on the lipid raft
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
17 October 2017
stated in
CC chemokine receptor 10 cell surface presentation in melanocytes is regulated by the novel interaction partner S100A10
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
17 October 2017
stated in
Annexin A2 mediates Mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin binding to eukaryotic cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
17 October 2017
stated in
Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
17 October 2017
stated in
Annexin A2 mediates Mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin binding to eukaryotic cells
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
17 October 2017
stated in
N-Terminal Polypeptide of Annexin A2 Decreases Infection of Mycoplasma hyorhinis to Gastric Cancer Cells
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
17 October 2017
stated in
Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IPI
protein binding
determination method or standard
IBA
IPI
19 references
retrieved
8 April 2019
stated in
Biochemical characterization of APPL endosomes: the role of annexin A2 in APPL membrane recruitment
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
Cochlin induced TREK-1 co-expression and annexin A2 secretion: role in trabecular meshwork cell elongation and motility
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
CEACAM1, a cell-cell adhesion molecule, directly associates with annexin II in a three-dimensional model of mammary morphogenesis
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
Annexin A2 mediates Mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin binding to eukaryotic cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
CC chemokine receptor 10 cell surface presentation in melanocytes is regulated by the novel interaction partner S100A10
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
Annexin A2 is a C-terminal PCSK9-binding protein that regulates endogenous low density lipoprotein receptor levels
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
N-Terminal Polypeptide of Annexin A2 Decreases Infection of Mycoplasma hyorhinis to Gastric Cancer Cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
The frontotemporal dementia mutation R406W blocks tau's interaction with the membrane in an annexin A2-dependent manner.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
Annexin A2 is involved in the formation of hepatitis C virus replication complex on the lipid raft
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
Angiogenin interacts with the plasminogen activation system at the cell surface of breast cancer cells to regulate plasmin formation and cell migration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
Annexin A2 mediates Mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin binding to eukaryotic cells
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
N-Terminal Polypeptide of Annexin A2 Decreases Infection of Mycoplasma hyorhinis to Gastric Cancer Cells
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IPI
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IBA
cell component
extracellular exosome
determination method or standard
IDA
7 references
retrieved
17 October 2017
stated in
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IDA
retrieved
17 October 2017
stated in
Protein profile of exosomes from trabecular meshwork cells
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IDA
retrieved
17 October 2017
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IDA
retrieved
17 October 2017
stated in
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IDA
retrieved
17 October 2017
stated in
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IDA
retrieved
17 October 2017
stated in
Ahnak1 abnormally localizes in muscular dystrophies and contributes to muscle vesicle release
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IDA
retrieved
17 October 2017
stated in
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07355&geneProductId=UniProtKB:P07355
determination method or standard
IDA
cytoplasm
determination method or standard
IBA
IDA
IEA
5 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IEA
retrieved
8 April 2019
stated in
Biochemical characterization of APPL endosomes: the role of annexin A2 in APPL membrane recruitment
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IDA
retrieved
8 April 2019
stated in
Annexin A2 mediates Mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin binding to eukaryotic cells
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IDA
retrieved
8 April 2019
stated in
N-Terminal Polypeptide of Annexin A2 Decreases Infection of Mycoplasma hyorhinis to Gastric Cancer Cells
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IBA
collagen-containing extracellular matrix
determination method or standard
HDA
ISS
5 references
retrieved
8 April 2019
stated in
Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
ISS
retrieved
8 April 2019
stated in
Comprehensive proteomic characterization of stem cell-derived extracellular matrices.
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
HDA
retrieved
8 April 2019
stated in
Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
HDA
retrieved
8 April 2019
stated in
Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
HDA
retrieved
8 April 2019
stated in
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
HDA
extracellular exosome
determination method or standard
HDA
IDA
6 references
retrieved
8 April 2019
stated in
Ahnak1 abnormally localizes in muscular dystrophies and contributes to muscle vesicle release
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
IDA
retrieved
8 April 2019
stated in
Protein profile of exosomes from trabecular meshwork cells
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
HDA
retrieved
8 April 2019
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
HDA
retrieved
8 April 2019
stated in
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
HDA
retrieved
8 April 2019
stated in
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
HDA
retrieved
8 April 2019
stated in
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
GOA
curator
UniProt
UniProt protein ID
P07355
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07355
determination method or standard
HDA
biological process
Gene Atlas image
PBB GE ANXA2 201590 x at fs.png
732 × 530; 11 KB
0 references

Identifiers

MeSH descriptor ID
C472822
subject named as
ANXA2 protein, human
0 references
Ensembl protein ID
 
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