Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development (Q28512255)

25 January 2017

title

Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development (English)

1 reference

Ligase IV, DNA, ATP-dependent

25 January 2017

main subject

1 reference

Ataxia telangiectasia mutated

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

J. Sekiguchi

1

0 references

author name string

D. O. Ferguson

2

1 reference

25 January 2017

H. T. Chen

3

1 reference

25 January 2017

E. M. Yang

4

1 reference

25 January 2017

J. Earle

5

1 reference

25 January 2017

K. Frank

6

1 reference

25 January 2017

S. Whitlow

7

1 reference

25 January 2017

Y. Gu

8

1 reference

25 January 2017

Y. Xu

9

1 reference

25 January 2017

A. Nussenzweig

10

1 reference

25 January 2017

F. W. Alt

11

1 reference

25 January 2017

language of work or name

English

0 references

publication date

13 March 2001

1 reference

Proceedings of the National Academy of Sciences of the United States of America

25 January 2017

published in

1 reference

25 January 2017

volume

98

1 reference

25 January 2017

issue

6

1 reference

25 January 2017

page(s)

3243–3248

1 reference

Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm

25 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Role for ATM in DNA damage-induced phosphorylation of BRCA1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

ATM-dependent phosphorylation of nibrin in response to radiation exposure

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Cancer-susceptibility genes. Gatekeepers and caretakers

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Atm-deficient mice: a paradigm of ataxia telangiectasia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Tying up loose ends: nonhomologous end-joining in Saccharomyces cerevisiae

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Mechanisms of DNA double-strand break repair and their potential to induce chromosomal aberrations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Analysis of ku80-mutant mice and cells with deficient levels of p53

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

The controlling role of ATM in homologous recombinational repair of DNA damage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

ATM: a mediator of multiple responses to genotoxic stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Multiple ATM-dependent pathways: an explanation for pleiotropy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Identification of genes involved in repair of DNA double-strand breaks in mammalian cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Critical telomere shortening regulated by the ataxia-telangiectasia gene acts as a DNA damage signal leading to activation of p53 protein and limited life-span of human diploid fibroblasts. A review

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

Mutations in the p53 and SCID genes cooperate in tumorigenesis.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30638

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.051632098

Inner and outer arm axonemal dyneins from the Antarctic rockcod Notothenia coriiceps

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.051632098

Nonhomologous end-joining proteins are required for V(D)J recombination, normal growth, and neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.051632098

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.051632098

Elongated Telomeres inscidMice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.051632098

21 January 2018

Identifiers

DOI

10.1073/PNAS.051632098

0 references

0 references

0 references

1 reference