Genetic evidence that SOST inhibits WNT signaling in the limb (Q28509512)

24 January 2017

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29 January 2020

title

Genetic evidence that SOST inhibits WNT signaling in the limb (English)

2 references

24 January 2017

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29 January 2020

1 reference

GOA release 2020-03-11

Low density lipoprotein receptor-related protein 6

1 reference

GOA release 2020-03-11

author

Damian C Genetos

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20359476%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Gabriela G Loots

5

1 reference

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29 January 2020

author name string

Deepa Murugesh

3

2 references

24 January 2017

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29 January 2020

Nicole M Collette

1

1 reference

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29 January 2020

Richard M Harland

4

1 reference

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29 January 2020

language of work or name

English

0 references

publication date

30 March 2010

1 reference

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29 January 2020

number of pages

11

1 reference

based on heuristic

inferred from page(s)

published in

Developmental Biology

2 references

24 January 2017

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29 January 2020

volume

342

2 references

24 January 2017

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29 January 2020

issue

2

2 references

24 January 2017

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29 January 2020

page(s)

169-179

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20359476%20AND%20SRC:MED&resulttype=core&format=json

Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis

29 January 2020

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Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation

19 March 2017

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Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist

19 March 2017

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Homozygous WNT3 mutation causes tetra-amelia in a large consanguineous family

19 March 2017

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Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

19 March 2017

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Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot

19 March 2017

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Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning

19 March 2017

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Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

19 March 2017

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Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)

19 March 2017

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Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein

19 March 2017

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19 March 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease

29 September 2017

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29 September 2017

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29 September 2017

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Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds.

29 September 2017

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29 September 2017

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Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling

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27 November 2018

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27 November 2018

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The limb bud Shh-Fgf feedback loop is terminated by expansion of former ZPA cells.

27 November 2018

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Role of BMP-2 and OP-1 (BMP-7) in programmed cell death and skeletogenesis during chick limb development.

27 November 2018

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Functional interaction of beta-catenin with the transcription factor LEF-1

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Bone Morphogenetic Protein-2 (BMP-2) Inhibits Muscle Development and Promotes Cartilage Formation in Chick Limb Bud Cultures

7 January 2021

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The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides

7 January 2021

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Multiple roles of mesenchymal -catenin during murine limb patterning

7 January 2021

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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

7 January 2021

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7 January 2021

Identifiers

DOI

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release_yglkc3bmojes3fvgacvt73inqa

29 January 2020

Fatcat ID

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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29 January 2020

2 references

24 January 2017