Brk, a breast tumor-derived non-receptor protein-tyrosine kinase, sensitizes mammary epithelial cells to epidermal growth factor (Q28298083)

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H E Jolin

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P J Mitchell

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K T Barker

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L E Jackson

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C J Dean

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M J Page

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B A Gusterson

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M R Crompton

Journal of Biological Chemistry

9

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language of work or name

English

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publication date

29 November 1996

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language of work

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volume

271

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issue

48

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page(s)

30956-63

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cites work

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Mutation of a site of tyrosine phosphorylation in the lymphocyte-specific tyrosine protein kinase, p56lck, reveals its oncogenic potential in fibroblasts

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Protein tyrosine kinase activity as a prognostic parameter in breast cancer, a pilot study.

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Association of INT2/HST1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis

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Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain

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Ductal morphogenesis in the mouse mammary gland: evidence supporting a role for epidermal growth factor

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Transforming growth factor alpha

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BRCA1 mutations in primary breast and ovarian carcinomas

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Distribution and number of epidermal growth factor receptors in skin is related to epithelial cell growth

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c-erbB-2 protein overexpression in breast cancer is a risk factor in patients with involved and uninvolved lymph nodes

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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

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Identification of heregulin, a specific activator of p185erbB2

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The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors

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PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex

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Acquisition of transforming properties by FYN, a normal SRC-related human gene

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Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Regulation of signal transduction and signal diversity by receptor oligomerization

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Expression of the ERBB3 gene product in breast cancer

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Transforming growth factor-alpha messenger RNA localization in the developing adult rat and human mammary gland by in situ hybridization.

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The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

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Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src

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Involvement of pp60c-src with two major signaling pathways in human breast cancer

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Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers

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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

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A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells

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Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity

21 January 2018

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Epidermal growth factor-related peptides in the pathogenesis of human breast cancer.

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Epidermal‐Growth‐Factor‐Dependent Activation of the Src‐Family Kinases

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Activation and translocation of c-Src to the cytoskeleton by both platelet-derived growth factor and epidermal growth factor

21 January 2018

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Functional interaction between the epidermal growth factor receptor and c‐Src kinase activity

21 January 2018

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A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

21 January 2018

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Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

21 January 2018

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The type I growth factor receptors in human breast cancer

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DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.

21 January 2018

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Expression in rat fibroblasts of a human transforming growth factor-alpha cDNA results in transformation

21 January 2018

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THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

21 January 2018

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Structural Basis of Interactions Between Epidermal Growth Factor Receptor and SH2 Domain Proteins

21 January 2018

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Analysis of proviral integration in human mammary epithelial cell lines immortalized by retroviral infection with a temperature-sensitive SV40 T-antigen construct

21 January 2018

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

21 January 2018

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Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function

21 January 2018

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pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src

21 January 2018

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Identification of the breast cancer susceptibility gene BRCA2

21 January 2018

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Transformation of NIH 3T3 fibroblasts by an activated form of p59hck

21 January 2018

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release_ua5iey3dsng3hprbiouhnjoqca

21 January 2018

Identifiers

DOI

10.1074/JBC.271.48.30956

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Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ua5iey3dsng3hprbiouhnjoqca