Aggresomes: a cellular response to misfolded proteins (Q28292275)

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7 December 2019

title

Aggresomes: a cellular response to misfolded proteins (English)

1 reference

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7 December 2019

1

1 reference

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7 December 2019

author name string

C L Ward

series ordinal

2

1 reference

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7 December 2019

R R Kopito

series ordinal

3

1 reference

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7 December 2019

language of work or name

English

0 references

publication date

1 December 1998

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7 December 2019

number of pages

16

1 reference

inferred from page(s)

published in

Journal of Cell Biology

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7 December 2019

volume

143

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7 December 2019

issue

7

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7 December 2019

page(s)

1883-1898

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The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61beta and a cytosolic, deglycosylated intermediary

7 December 2019

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Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

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Degradation of CFTR by the ubiquitin-proteasome pathway

7 April 2017

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The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

7 April 2017

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7 April 2017

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Membrane trafficking of the cystic fibrosis gene product, cystic fibrosis transmembrane conductance regulator, tagged with green fluorescent protein in madin-darby canine kidney cells

7 April 2017

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Lactacystin, proteasome function, and cell fate

29 September 2017

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Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome

29 September 2017

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Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation

29 September 2017

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29 September 2017

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Inhibition of autophagy abrogates tumour necrosis factor alpha induced apoptosis in human T-lymphoblastic leukaemic cells.

29 September 2017

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The proteasome: a macromolecular assembly designed to confine proteolysis to a nanocompartment

29 September 2017

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Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome

29 September 2017

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Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

29 September 2017

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Biosynthesis, processing, and targeting of sphingolipid activator protein (SAP )precursor in cultured human fibroblasts. Mannose 6-phosphate receptor-independent endocytosis of SAP precursor

29 September 2017

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Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

29 September 2017

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29 September 2017

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29 September 2017

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The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70 and degraded in a pre-Golgi nonlysosomal compartment

29 September 2017

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Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis

29 September 2017

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An integral membrane component of coatomer-coated transport vesicles defines a family of proteins involved in budding

29 September 2017

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The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

29 September 2017

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Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP

29 September 2017

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Isolation and partial characterization of a cage of filaments that surrounds the mammalian mitotic spindle

29 September 2017

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Translocation and clustering of endosomes and lysosomes depends on microtubules

29 September 2017

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Pre-Golgi degradation of newly synthesized T-cell antigen receptor chains: intrinsic sensitivity and the role of subunit assembly

29 September 2017

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Intermediate filaments and ubiquitin: a new thread in the understanding of chronic neurodegenerative diseases.

29 September 2017

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Ubiquitin in health and disease.

29 September 2017

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Misfolding and aggregation of newly synthesized proteins in the endoplasmic reticulum

29 September 2017

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Different intermediate-sized filaments distinguished by immunofluorescence microscopy

29 September 2017

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Isolation and preliminary characterization of 10-nm filaments from baby hamster kidney (BHK-21) cells

29 September 2017

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Role of the proteasome in membrane extraction of a short-lived ER-transmembrane protein

29 September 2017

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Proteolysis and the G1-S transition: the SCF connection

2 June 2018

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2 June 2018

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2 June 2018

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Structural neurology: are seeds at the root of neuronal degeneration?

2 June 2018

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Roles of ubiquitin-mediated proteolysis in cell cycle control

2 June 2018

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2 June 2018

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Endoplasmic reticulum degradation: reverse protein flow of no return

2 June 2018

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Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors

2 June 2018

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Neuronal localization of presenilin-1 and association with amyloid plaques and neurofibrillary tangles in Alzheimer's disease.

2 June 2018

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Light and electron microscopic localization of presenilin-1 in primate brain.

2 June 2018

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ER quality control: the cytoplasmic connection

2 June 2018

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Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins.

2 June 2018

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The gene defects responsible for familial Alzheimer's disease

2 June 2018

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Heat shock causes protein aggregation and reduced protein solubility at the centrosome and other cytoplasmic locations

2 June 2018

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A putative protein-sequestration site involving intermediate filaments for protein degradation by autophagy. Studies with transplanted Sendai-viral envelope proteins in HTC cells

2 June 2018

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Intermediate filament-ubiquitin diseases: implications for cell sanitization.

2 June 2018

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Dynamic properties of intermediate filaments: disassembly and reassembly during mitosis in baby hamster kidney cells

2 June 2018

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A general method for rapid site-directed mutagenesis using the polymerase chain reaction.

2 June 2018

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Intermediate filament reorganization during mitosis is mediated by p34cdc2 phosphorylation of vimentin

2 June 2018

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Both N-terminal and C-terminal fragments of presenilin 1 colocalize with neurofibrillary tangles in neurons and dystrophic neurites of senile plaques in Alzheimer's disease

2 June 2018

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Cytosolic degradation of T-cell receptor alpha chains by the proteasome

27 November 2018

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Multiple proteolytic systems, including the proteasome, contribute to CFTR processing

27 November 2018

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Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteins

27 November 2018

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The hydrophobic effect contributes to polyubiquitin chain recognition

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864362

12 December 2020

Phosphorylation of vimentin by Rho-associated kinase at a unique amino-terminal site that is specifically phosphorylated during cytokinesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864362

12 December 2020

Subcellular distribution and turnover of presenilins in transfected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864362

12 December 2020

Differential inhibition of calpain and proteasome activities by peptidyl aldehydes of di-leucine and tri-leucine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864362

12 December 2020

Protein topology of presenilin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864362

12 December 2020

Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864362

12 December 2020

The alpha chain of the T cell antigen receptor is degraded in the cytosol

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864362

12 December 2020

Estimation of the Genetic Contribution of Presenilin-1 and -2 Mutations in a Population-Based Study of Presenile Alzheimer Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864362

12 December 2020

Molecular and cellular effects of heat-shock and related treatments of mammalian tissue-culture cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864362

12 December 2020

Observations on the vimentin-10-NM filaments during mitosis in BHK21 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864362

12 December 2020

Site-specific phosphorylation induces disassembly of vimentin filaments in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864362

12 December 2020

Identifiers

DOI

10.1083/JCB.143.7.1883

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9864362%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9864362%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

PubMed publication ID

9864362

2 references