Molecular mechanism of Thioflavin-T binding to amyloid fibrils (Q28279924)

Biochimica et Biophysica Acta

Europe PubMed Central

title

Molecular mechanism of Thioflavin-T binding to amyloid fibrils (English)

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2

Shohei Koide

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Matthew Biancalana

object named as

Matthew Biancalana

series ordinal

1

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language of work or name

English

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publication date

July 2010

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published in

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volume

1804

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issue

7

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page(s)

1405-12

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cites work

The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds

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Branching in amyloid fibril growth

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Multivalent & multifunctional ligands to beta-amyloid

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The binding of thioflavin T and its neutral analog BTA-1 to protofibrils of the Alzheimer's disease Abeta(16-22) peptide probed by molecular dynamics simulations

29 September 2017

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Atomic structures of peptide self-assembly mimics

29 September 2017

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Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42.

29 September 2017

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29 September 2017

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29 September 2017

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Structures for amyloid fibrils

29 September 2017

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Mechanism of thioflavin T binding to amyloid fibrils.

29 September 2017

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Detection and characterization of aggregates, prefibrillar amyloidogenic oligomers, and protofibrils using fluorescence spectroscopy

29 September 2017

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Molecular basis for amyloid fibril formation and stability

29 September 2017

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The binding of thioflavin-T to amyloid fibrils: localisation and implications

29 September 2017

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A general model for amyloid fibril assembly based on morphological studies using atomic force microscopy

29 September 2017

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29 September 2017

Amyloid fibril proteins

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Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy

29 September 2017

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Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

29 September 2017

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Conformation of twisted β-pleated sheets in proteins

2 June 2018

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Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1.

2 June 2018

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Fluorometric examination of tissue amyloid fibrils in murine senile amyloidosis: use of the fluorescent indicator, thioflavine T.

2 June 2018

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Binding of the dye congo red to the amyloid protein pig insulin reveals a novel homology amongst amyloid-forming peptide sequences

2 June 2018

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Binding modes of thioflavin-T to the single-layer beta-sheet of the peptide self-assembly mimics

2 June 2018

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Interactions of thioflavin T with serum albumins: spectroscopic analyses.

27 November 2018

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Rifampicin does not prevent amyloid fibril formation by human islet amyloid polypeptide but does inhibit fibril thioflavin-T interactions: implications for mechanistic studies of beta-cell death

27 November 2018

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Chiral bifurcation in aggregating insulin: an induced circular dichroism study

27 November 2018

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On the binding of Thioflavin-T to HET-s amyloid fibrils assembled at pH 2.

27 November 2018

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Secondary nucleation and accessible surface in insulin amyloid fibril formation.

27 November 2018

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Inhibition of beta-amyloid peptide aggregation and neurotoxicity by alpha-d-mannosylglycerate, a natural extremolyte

27 November 2018

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Physical basis of colors seen in Congo red-stained amyloid in polarized light

27 November 2018

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Computational Study of Thioflavin T Torsional Relaxation in the Excited State

27 November 2018

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Dual binding modes of Congo red to amyloid protofibril surface observed in molecular dynamics simulations

27 November 2018

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Chiral bias of amyloid fibrils revealed by the twisted conformation of Thioflavin T: an induced circular dichroism/DFT study

27 November 2018

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Beta2-microglobulin amyloidosis: insights from conservation analysis and fibril modelling by protein docking techniques

27 November 2018

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Arrangement of subunits and ordering of beta-strands in an amyloid sheet

27 November 2018

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Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain

27 November 2018

1 reference

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Effect of environmental factors on the kinetics of insulin fibril formation: elucidation of the molecular mechanism

27 November 2018

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Stopped-flow kinetics reveal multiple phases of thioflavin T binding to Alzheimer beta (1-40) amyloid fibrils

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880406

Selective amyloid staining as a function of amyloid composition and structure. Histochemical analysis of the alkaline Congo red, standardized toluidine blue, and iodine methods.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880406

A historical note on the iodine-sulphuric acid reaction of amyloid

27 November 2018

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https://pubmed.ncbi.nlm.nih.gov/20399286

12 December 2020

Beta-pleated sheet fibrils. A comparison of native amyloid with synthetic protein fibrils

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https://pubmed.ncbi.nlm.nih.gov/20399286

12 December 2020

Study on the binding of Thioflavin T to β-sheet-rich and non-β-sheet cavities

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https://pubmed.ncbi.nlm.nih.gov/20399286

12 December 2020

Kinetics of Different Processes in Human Insulin Amyloid Formation

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https://pubmed.ncbi.nlm.nih.gov/20399286

12 December 2020

Binding mode of Thioflavin T in insulin amyloid fibrils

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https://pubmed.ncbi.nlm.nih.gov/20399286

12 December 2020

Fluorescent stains, with special reference to amyloid and connective tissues

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https://pubmed.ncbi.nlm.nih.gov/20399286

12 December 2020

Kinetic analysis of amyloid fibril polymerization in vitro

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https://pubmed.ncbi.nlm.nih.gov/20399286

12 December 2020

10.1016/J.BBAPAP.2010.04.001

Identifiers

DOI

1 reference

1 reference

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PubMed publication ID

20399286

1 reference